Efficacy and Safety of Laser Surgery and Transurethral Resection of the Prostate for Treating Benign Prostate Hyperplasia: a Network Meta-analysis

Wang, Li,Yu, Qiu-Yan,Liu, Yan,Zhu, Zhen-Li,Huang, Yuan-Wei,Li, Ke Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9

Background: Traditional meta-analyses or systematic reviews of randomized controlled trials (RCTs) have been used to compare laser surgeries and transurethral resection of the prostate (TURP) for benign prostate hyperplasia (BHP), but they cannot provide a hierarchy regarding efficacy and safety of treatment. Objective: We therefore performed a network meta-analysis (NMA) to compare and create hierarchies for efficacy and safety of TUPR and laser surgeries for BPH. Materials and Methods: We searched for reports of RCTs published up to April 25, 2015. After methodological quality assessment and data extraction, we performed an NMA to compare TURP and laser surgeries for BPH. Results: We ranked the treatments of TURP and laser surgeries for BPH. For IPSS at 6 months, holmium laser resection of the prostate (HoLRP) ranked the first-best and at 12 months, holmium laser enucleation of the prostate (HoLEP). For Qmax at 6 and 12 months, HoLEP ranked the first-best; for operative time it was TURP; for cathedral removal time, diode laser enucleation of the prostate (DiLEP) ranked the first-best. Conclusions: Although TURP is considered the gold standard for treating BPH, it is not better in terms of efficacy and safety compared with the laser surgery. Our NMA created hierarchies for the 9 types of surgery in terms of efficacy and safety, which should help clinicians choose the best approach for the individual patient.

Novel Environmentally Friendly Manufacturing Method for Micro-Textured Cutting Tools

Changping Li,Xinyi Qiu,Zhen Yu,Shujian Li,Pengnan Li,Qiulin Niu,Rendi Kurniawan,고태조 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.1

Surface texturing on cutting tools has a great influence on reducing the friction force between tool and chip interfaces. In this study, a grinding method was developed to fabricate micro-groove textures on cutting tools using a special diamond grinding wheel on the tool rake face. A comparative experiment was done using a laser and other grinding method to fabricate micro-grooves. The developed grinding method does not produce harmful gases, it is environmentally friendly, and it fabricates groove textures with high efficiency and quality. Various micro-grooves with depths of 30–90 μm, groove pitches of 0.5–1 mm, and groove angles of 30–60 o were made on the rake faces of non-coated end-mill tools using the developed grinding method. Milling experiments on aluminum alloy (Al6061-T6) and tool steel (SKD11) with non-water-soluble coolant were carried out using the textured tools, and the cutting force and tool wear were investigated. In most cases, the cutting force produced by the micro-grooved tools is significantly reduced. In addition, the wear resistance of the micro-groove cutting tool is better than that of a conventional cutting tool, and there is no chipping.

Isoindolin-1-ones from the stems of Nicotiana tabacum and their antiviral activities

Guang-Yu Yang,Jia-Meng Dai,Zhen-Jie Li,Jin Wang,Feng-Xian Yang,Xin Liu,Jing Li,Qian Gao,Xue-Mei Li,Yin-Ke Li,Wei-Guang Wang,Min Zhou,Qiu-Fen Hu 대한약학회 2022 Archives of Pharmacal Research Vol.45 No.8

In previous studies, several isoindolin-1-oneanalogs that exhibited signifi cant anti-tobacco mosaic virus(anti-TMV) activities were isolated from Nicotiana tabacum . Since gene-editing mutants provide a new sample for thediscovery of active metabolites, we focused on the stems ofYN-18–23 (a mutant N. tabacum for gene editing with thealkaloid metabolic pathway cultivated by Yunnan TobaccoCompany), which led to the isolation of four new ( 1–4 )and four known ( 5–8 ) isoindolin-1-ones. To the best of ourknowledge, nicindole C ( 3 ) is the fi rst subclass of isoindolin-1-one bearing a pentacyclic ketone, while nicindole D ( 4 )is the fi rst example of isoindolin-1-one bearing a methylpyridin-2-(1 H )-one moiety. Compounds 1–4 were testedfor their anti-TMV activities, and the results revealed thatcompounds 1 , 3 , and 4 exhibited high anti-TMV activities atconcentrations of 20 μM with inhibition rates of 48.6, 42.8,and 71.5%, respectively. These rates are higher than the inhibitionrate of the positive control (33.2%). The mechanisticstudy of compound 4 , which had the highest anti-TMV activityrevealed that increased potentiation of defense-related enzyme activities and downregulation of expression of theNtHsp70 protein may induce resistance in tobacco againstthe viral pathogen TMV. Molecular docking studies alsorevealed that the isoindolin-1-one substructure is fundamentalfor anti-TMV activity. The methyl-pyridin-2-(1 H )-onemoiety in compound 4 and the 2-oxopropyl groups in compounds1 and 3 at the N -2 position may increase inhibitoryactivities. This study of the structure–activity relationshipis helpful for fi nding new anti-TMV activity inhibitors. Tostudy whether the isoindolin-1-ones have broader antiviralactivities, compounds 1–4 were also tested for their antirotavirusactivities. Compound 4 exhibited high anti-rotavirusactivity with a therapeutic index (TI) value of 20.7. This TI value is close to that of the positive control (20.2).

Does matching relation exist between the length and the tilting angle of terminal implants in the all-on-four protocol? stress distributions by 3D finite element analysis

Li, Xiaomei,Cao, Zhizhong,Qiu, Xiaoqian,Tang, Zhen,Gong, Lulu,Wang, Dalin The Korean Academy of Prosthodonitics 2015 The Journal of Advanced Prosthodontics Vol.7 No.3

PURPOSE. To explore whether there is matching relation between the length and the tilting angle of terminal implants in the All-on-Four protocol by studying the effects of different implant configurations on stress distributions of implant, bone, and framework. MATERIALS AND METHODS. Four implants were employed to support a full-arch fixed prosthesis and five three-dimensional finite element models were established with CT images, based on the length (S and L) and distal tilt angle ($0^{\circ}$, $30^{\circ}$ and $45^{\circ}$) of terminal implants for an edentulous mandible, which named: Tilt0-S, Tilt30-S, Tilt30-L, Tilt45-S and Tilt45-L. An oblique 240 N was loaded at second molar. The von Mises Stresses were analyzed. The implants were consecutively named #1 to #4 from the loading point. RESULTS. 1) Tilt0-S had the greatest stress on the implants, with the other groups exhibiting variable reductions; the four implants of Tilt45-L demonstrated the greatest reduction in stress. 2) Tilt0-S had the greatest stress at bone around #1 implant neck, and Tilt45-L exhibited the least stress, which was a 36.3% reduction compared to Tilt0-S. 3) The greatest stress in the framework was found on the cantilevers distal to #1 implant. Tilt45-S exhibited the least stress. CONCLUSION. Matching different length and tilting angle of the terminal implants led to variable stress reductions on implants, bone and the superstructure. By optimizing implant configuration, the reduction of stress on implants and surrounding bone could be maximized. Under the present condition, Tilt45-L was the preferred configuration. Further clinical testings are required.

Does matching relation exist between the length and the tilting angle of terminal implants in the all-on-four protocol? stress distributions by 3D finite element analysis

Zhen Tang,Lulu Gong,Dalin Wang,Xiaoqian Qiu,Zhizhong Cao,Xiaomei Li 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.3

PURPOSE To explore whether there is matching relation between the length and the tilting angle of terminal implants in the All-on-Four protocol by studying the effects of different implant configurations on stress distributions of implant, bone, and framework. MATERIALS AND METHODS Four implants were employed to support a full-arch fixed prosthesis and five three-dimensional finite element models were established with CT images, based on the length (S and L) and distal tilt angle (0°, 30° and 45°) of terminal implants for an edentulous mandible, which named: Tilt0-S, Tilt30-S, Tilt30-L, Tilt45-S and Tilt45-L. An oblique 240 N was loaded at second molar. The von Mises Stresses were analyzed. The implants were consecutively named #1 to #4 from the loading point. RESULTS 1) Tilt0-S had the greatest stress on the implants, with the other groups exhibiting variable reductions; the four implants of Tilt45-L demonstrated the greatest reduction in stress. 2) Tilt0-S had the greatest stress at bone around #1 implant neck, and Tilt45-L exhibited the least stress, which was a 36.3% reduction compared to Tilt0-S. 3) The greatest stress in the framework was found on the cantilevers distal to #1 implant. Tilt45-S exhibited the least stress. CONCLUSION Matching different length and tilting angle of the terminal implants led to variable stress reductions on implants, bone and the superstructure. By optimizing implant configuration, the reduction of stress on implants and surrounding bone could be maximized. Under the present condition, Tilt45-L was the preferred configuration. Further clinical testings are required.

Novel Method for Circulating Current Suppression in MMCs Based on Multiple Quasi-PR Controller

Qiu, Jian,Hang, Lijun,Liu, Dongliang,Geng, Shengbao,Ma, Xiaonan,Li, Zhen The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.6

An improved circulating current suppression control method is proposed in this paper. In the proposed controller, an outer loop of the average capacitor voltage control model is used to balance the sub-module capacitor voltage. Meanwhile, an individual voltage balance controller and an arm voltage balance controller are also used. The DC and harmonic components of the circulating current are separated using a low pass filter. Therefore, a multiple quasi-proportional-resonant (multi-quasi-PR) controller is introduced in the inner loop to eliminate the circulating harmonic current, which mainly contains second-order harmonic but also contains other high-order harmonics. In addition, the parameters of the multi-quasi-PR controller are designed in the discrete domain and an analysis of the stability characteristic is given in this paper. In addition, a simulation model of a three-phase MMC system is built in order to confirm the correctness and superiority of the proposed controller. Finally, experiment results are presented and compared. These results illustrate that the improved control method has good performance in suppressing circulating harmonic current and in balancing the capacitor voltage.

Rockburst occurrences and microseismicity in a longwall panel experiencing frequent rock bursts

Zhen-lei Li,Xue-qiu He,Lin-ming Dou,Gui-feng Wang 한국지질과학협의회 2018 Geosciences Journal Vol.22 No.4

A rockburst is a kind of dynamic geological hazard faced by engineers and researchers. Identification of a potential rockburst risk area (PRBRA) allows effective, targeted measures to be taken mitigate these hazards. To provide a reference for determining PRBRA in longwall panels with similar conditions, an in situ investigation that lasted for over three years was conducted on LW3401 in the Junde coal mine which experienced a total of 22 rockbursts. The investigation involves rockburst consequences (including the location, length, degree, and modes of the ensuing damage), seismic features of rockburst (including the source and seismic energy), and the relationship between rockbursts and microseismicity. Results show that damaged areas are mostly within the 18 m behind the excavation face, or up to 30 m ahead of the coalface. Lengths of damaged sections of roadways are within 95 m (and 115 m) during roadway excavation (and coalface advancing operations). The seismic energy of rockbursts ranges from 1.60 × 104 to 8.21 × 106 J. Sources of rockbursts lie mostly within 145 m of damage locations. Before a rockburst, sources of microseismic (MS) events begin to cluster around the roadway or coalface. Daily total energy and MS event counts rose, then fell, before a rockburst occurred. PRBRAs in a roadway lie within a certain distance behind the excavation face, or ahead of the coalface. When high-energy MS events are found in close proximity to a PRBRA, the rockburst risk in a given panel increases.

Effects of Glycinin Basic Polypeptide on Sensory and Physicochemical Properties of Chilled Pork

Ying-Qiu Li,Man Hao,Jie Yang,Hai-Zhen Mo 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.3

Effects of glycinin basic polypeptide (GBP) on sensory and physicochemical properties of pork during chilled storage were investigated. Pork treated with GBP was analyzed periodically for sensory properties, pH, total volatile base nitrogen (TVB-N), α-thiobarbituric acid (TBA), and total viable count (TVC) values. Compared with controls, TBA values of pork treated with GBP did not change. TVB-N, pH, and TVC values of pork showed reductions with increasing concentrations of GBP during 8 days of storage. However, there were increases in sensory scores. TVC values of treated pork showed a positive linear relationship with both pH and TVB-N values. GBP at 0.16 and 0.20% efficiently inhibited bacterial growth, and enhanced chilled pork sensory scores. Therefore, GBP has potential as a pork biological preservative for extension of shelf life during chilled storage.

Novel Method for Circulating Current Suppression in MMCs Based on Multiple Quasi-PR Controller

Jian Qiu,Lijun Hang,Dongliang Liu,Shengbao Geng,Xiaonan Ma,Zhen Li 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.6

An improved circulating current suppression control method is proposed in this paper. In the proposed controller, an outer loop of the average capacitor voltage control model is used to balance the sub-module capacitor voltage. Meanwhile, an individual voltage balance controller and an arm voltage balance controller are also used. The DC and harmonic components of the circulating current are separated using a low pass filter. Therefore, a multiple quasi-proportional-resonant (multi-quasi-PR) controller is introduced in the inner loop to eliminate the circulating harmonic current, which mainly contains second-order harmonic but also contains other high-order harmonics. In addition, the parameters of the multi-quasi-PR controller are designed in the discrete domain and an analysis of the stability characteristic is given in this paper. In addition, a simulation model of a three-phase MMC system is built in order to confirm the correctness and superiority of the proposed controller. Finally, experiment results are presented and compared. These results illustrate that the improved control method has good performance in suppressing circulating harmonic current and in balancing the capacitor voltage.

Network Characteristics Analysis of Microblog Public Opinion

Lirong Qiu,Jie Li,Zhen Hai Zhang,Yi Lei Wang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

This paper uses public opinion propagation structure of Sina microblog as research object, it sets up simulation model of public opinion propagation structures based on complex network theory. Through the analysis of the degree distribution, clustering coefficient and community structure of the model, the validity of the model has been well confirmed. The paper also conducts research and analysis towards propagation quantity of the hot topic within 800 well-known spread microblog from 2013 to 2015, the paper establishes a community structure, through the simulation and demonstration of the community structure, it declares the community structure characteristic under the complex network environment.