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LEE, Sung-Rae,LEE, Ser-Hoon,HWANG, Sun-Young The Institute of Electronics, Information and Comm 2010 IEICE transactions on information and systems Vol.93 No.8
<P>This paper presents an efficient instruction scheduling algorithm which generates low-power codes for embedded system applications. Reordering and recoding are concurrently applied for low-power code generation in the proposed algorithm. By appropriate reordering of instruction sequences, the efficiency of instruction recoding is increased. The proposed algorithm constructs program codes on a basic-block basis by selecting a code sequence from among the schedules generated randomly and maintained by the system. By generating random schedules for each of the basic blocks constituting an application program, the proposed algorithm constructs a histogram graph for each of the instruction fields to estimate the figure-of-merits achievable by reordering instruction sequences. For further optimization, the system performs simulated annealing on the generated code. Experimental results for benchmark programs show that the codes generated by the proposed algorithm consume 37.2% less power on average when compared to the previous algorithm which performs list scheduling prior to instruction recoding.</P>
Effect of Dominant Versus Non-dominant Vision in Postural Control
Rae-Young Park,Soe-Ra Yoon,Hoi-Sung Kee,Jung-Ho Kang,Su-Jin Lee,Kwang-Ik Jung 대한재활의학회 2011 Annals of Rehabilitation Medicine Vol.35 No.3
Objective To assess the eff ect of dominant and non-dominant vision in controlling posture in quiet stance. Method Twenty-fi ve healthy elderly subjects aged over 60 years old and twenty-fi ve young subjects aged under 30 years old were assessed by computerized dynamic posturography. Postural stability was measured in two conditions; dominant eye open and non-dominant eye open. We used the sensory organization test (SOT) for evaluating sensory impairment. A SOT assessed the subject’s ability to use and integrate somatosensory input,vision, and vestibular cueseff ectively to maintain balance. The SOT was conducted 3 times, and the average value of the 3 trials was used for data analysis. Equilibrium scores reflected the subject’s anteroposterior sway. The highest possible score was 100, which indicated that the subject did not sway at all, and a score of 0 indicated a fall from the footplate. Determination of ocular dominance was performed by a hole-in-the card test. Results For the twenty-five young subjects in this study, equilibrium score in two conditions did not differ. However, for elderly subjects over 60 years, the equilibrium score in dominant vision was higher than in nondominant vision (p<0.05). Conclusion In young subjects, there were no signifi cant diff erences in postural control between dominant vision and non-dominant vision. However, in elderly subjects, postural control in non-dominant vision was signifi cantly impaired. Therefore, the evaluation of a dominant eye should be considered in rehabilitation programs for elderly people.
Comparison of Developmental Competence of Oocytes Aspirated from in Hanwoo Native Cows
Sang-Rae Cho,Sung-Sik Kang,Ui-Hyung Kim,Seok-Dong Lee,Myung-Suk Lee 한국동물생명공학회(구 한국동물번식학회) 2018 발생공학 국제심포지엄 및 학술대회 Vol.2018 No.06
The aim of the present study was investigated to determine optimal culture condition for IVP embryos using oocytes derived from follicles of ovum pick-up (OPU). Follicular oocytes were aspirated from Hanwoo native cows by the OPU method. After follicular aspiration, the number and morphology of cumulus-oocytes complexes (COCs) and the developmental competence of oocytes after in vitro maturation (IVM), in vitro fertilization (IVF) and in vitro culture were evaluated. The quality of aspirated COCs did not differ among the individual donor. The rates of oocytes recovery from the follicles by ultasound-guided aspiration were not significantly different among individual, but the rate of oocytes useful for IVF was significantly higher (p<0.05) in cows (67%) than heifers (45%) The cleavage and the developmental rate to blastocysts was not significantly different between CR1aa and IVMD medium. In conclusion, the culture medium did not have any apparent effects on the quality of aspirated COCs and developmental competence of oocytes after IVM-IVF, but it may affect follicular recruitment in non-pregnant cows. Moreover, the reproductive phase may influence the developmental competence of the recovered oocytes.
Sung-Sik Kang,Sang-Rae Cho,Ui-Hyung Kim,Seok-Dong Lee,Myung-Suk Lee,Boh-Suk Yang 한국동물생명공학회(구 한국동물번식학회) 2018 발생공학 국제심포지엄 및 학술대회 Vol.2018 No.06
In the present study, we compared cauda epididymal sperm recovery methods in Hanwoo bulls by flushing and floating techniques. Fourteen testicles with epididymides were collected from 7 Hanwoo bulls (months of age=15.1±0.2, scrotal circumference (cm)=31.6±1.1, weight (kg)=391.1±16.6. Epididymis with vas deferens in each bull was isolated from testis and blood vessels on surface of cauda epididymis. To recover cauda epididymal sperm by flushing and floating, each testis was randomly selected from a pair of testicles. The mean weight, length, width, circumference of testicles were similar. For flushing method, a 26 gauge needle connected with 10 mL syringe was inserted into the duct of vas deference. About 12 to 15 incisions were made in cauda epididymis. Pre-warmed semen freezing medium (OptixCell, IMV, France) flushed and epididymal sperm were recovered. For floating method, cauda epididymis was cut and minced using blades in a 100 mm dish. Minced cauda epididymis tissues were incubated with 10 mL of semen freezing medium for 15 min at room temperature. Sperm suspension recovered by filteration with a cell strainer (100 μM nylon mesh). Sperm concentration adjusted to 40 to 50×106 cells/mL with semen freezing medium, semen dilution loaded to 0.5 mL straw and cryopreserved in liquid nitrogen tank. Frozen-semen was thawed at 37°C for 40 sec and measured sperm motility and motility parameters using a CASA system (sperm class analyzer, Spain). Five replicates were conducted in each experimental group of bull. Recovered semen volume (63.3±28.0 vs. 61.7±23.0 mL), motility (89.5±12.8 vs. 91.4±7.9%) among flushing and floating methods were not significantly different. In conclusion, the both of flushing and floating techniques can be used for cauda epididymal sperm recovery without difference of sperm quality.
Evaluation of Bone-union Efficiency of collagen coated Peek Using beagle dog
Rae-Hyung Ryu,Sang Woo Kim,Seon Won Lee,Do Hyun Lee,Eun Hee Kim 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7
Spinal fusion is a surgical procedure that reduce patient pain by relieving nerve compression due to disc degeneration. This procedure restores the disk height of the lowered intervertebral disc due to degeneration and fixes the movement of the vertebral segments in the lesion by inserting an implant in the spinal segment of the patient. However, there is a side effect that the patient’s postoperative recovery rate is slow and the movement of the lesion segment is not fixed effectively because of the delayed union between the inserted intervertebral body and the vertebra. In order to improve these problems, Jeil Medical Co, Ltd developed a product that coated the surface of PEEK with collagen and Osong Medical Innovation Foundation Laboratory Animal Center (KBIO-LAC) applied it to the tibia of beagle to evaluate its effectiveness. At 5 and 10 weeks after transplantation the tibia bone was removed and micro-CT and histology analysis were performed. Results of micro-CT analysis showed the BMD and bone volume of liquid collagen coated PEEK implants area were higher than those of other implants area at 5 and 10 weeks. Histological analysis of bone stained with Villanueva showed that the distribution of bone formation was greater in the periphery of the HA-blasting PEEK than in the periphery of the bare PEEK at 4 weeks of transplantation, and the density of the peripheral bone tissue of the HA-blasting PEEK at 8 weeks was higher than that of the bare PEEK. As a result, the effectiveness of HA blasting PEEK was confirmed, and it was found that the peripheral bone tissue was formed relatively better than bare PEEK.
Lee, Choon-Taek,Park, Mi Young,Kim, Dal Rae,Choi, Eun Kyung,Yoo, Chul-Gyu,Kim, Young Whan,Han, Sung Koo,Shim, Young-Soo,Kim, Yeon-Soo D. A. Spandidos 2009 MOLECULAR MEDICINE REPORTS Vol.2 No.3
<P>Radiation is one of the main treatment modalities in lung cancer, but low sensitivity and acquired resistance of lung cancer cells to radiation frequently result in treatment failure. The activation of nuclear factor (NF)-κB is reportedly the main mechanism by which cancer cells exhibit resistance to external stresses, such as chemotherapy or radiation therapy. In this study, we blocked the activation of NF-κB by adenovirus-expressing IκBα-SR and investigated the effect this had on radiation sensitivity. Transduction with ad-IκBα effectively blocked the activation of NF-κB by radiation in all the cancer cell lines tested, except for NCI H460. Clonogenic assay after radiation demonstrated that ad-IκBα transduction enhanced the sensitivity to radiation of the lung cancer cell lines and HeLa cells, except for NCI H460. The radiosensitizing effect of IκBα was more potent in lung cancer cell lines with radioresistance (SKMESres) (sensitizer enhancement ratio 1:61). From these findings, NF-κB blockade by ad-IκBα enhanced the radiation sensitivity and also abolished the acquired radiation resistance of lung cancer cell lines. This study provides a therapeutic rationale for combining an NF-κB-blocking strategy with radiation to both increase sensitivity and overcome acquired resistance to radiation.</P>
Sung-Sik Kang,Ui-Hyung Kim,Seok-Dong Lee,Myung-Suk Lee,Man-Hye Han,Sang-Rae Cho 한국동물생명공학회(구 한국동물번식학회) 2019 Journal of Animal Reproduction and Biotechnology Vol.34 No.4
This study was conducted to examine the oocyte recovery efficiency through having an OPU session once and twice a week. Also, the oocyte recovery efficiency was examined by using OPU after two and three months of rest period. Six cows were used for oocytes collection and were randomly divided into two groups. In experiment 1, OPU sessions were conducted once and twice a week to collect oocytes. The collected oocytes between once and twice OPU groups were classified into four groups (grade 1, 2, 3 and 4) according to the quality of cumulus cells and ooplasm. Based on the result, the percentage of collected oocytes per aspirated follicle number was similar between once and twice OPU session groups (65.5 ± 1.9 and 68.7 ± 1.4 vs.). However, the percentage of grade 1 oocytes from the twice OPU session group was significantly high compared with that of the once a week OPU session group (25.3 ± 0.9 and 32.5 ± 1.2% vs. once and twice session group, respectively, p < 0.05). In experiment 2, the group with three months of rest period tended to have a high percentage of collected oocyte compared with the group with two months of rest period (64.6 and 70.9% vs. 2 and 3 months rest group, respectively, p = 0.62). The percentage of grade 4 in the group with three months of rest period was significantly low compared with the group with two months of rest period group (27.3 and 36.5% vs. two and three months rest group, respectively, p = 0.05). In conclusion, twice a week OPU session is suitable for collection of high quality oocytes by using OPU, and three months of rest period is needed for the recovery of oocyte quality of a donor cow.