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Quench Detection of the KSTAR CS Coil by Considering Plasma Current Effect
Kim, Jinsub,Jeon, Young Mu,Yonekawa, Hirofumi,Kim, Yeong-ok,Kim, Kwang Pyo,Park, K. R.,Chu, Yong Institute of Electrical and Electronics Engineers 2019 IEEE transactions on applied superconductivity Vol.29 No.5
<P>The plasma-driven inductive voltages were not negligible and should be taken into account for the reliable operation of the voltage-based quench detection of the KSTAR CS coil. For the active compensation of such plasma-induced voltage noise, plasma parameters should be measured in real-time and applied to the quench detection system. The selection of plasma parameters by considering their contribution to the noise is of primary importance. A code, which can estimate the induced coil voltage driven by plasma, is developed by using a simplified plasma response modeling. The numerical analysis has showed that there is an apparent influence from the plasma, while the influence from eddy currents induced in passive structures is negligible. The change of plasma current is the primary noise source and the radial and vertical motions of plasma have an effect, although they are small. The performance of the quench detector is developed and tested during the 2017 KSTAR campaign. The noise rejection performance is discussed with various experimental results and numerical estimations.</P>
Kim, Hyun-Ju,Noh, Jeong-Sook,Kwon, Myung-Ja,Song, Su-Hee,Suh, Hong-Suk,Kim, Mi-Jeong,Song, Yeong-Ok Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.11
We investigated the effects of newly synthesized 4-[(butylsulfinyl)methyl]-1,2-benzenediol (SMBD) on the prevention of atherosclerosis in hypercholesterolemic rabbits. SMBD exhibited stronger inhibition of $Cu^{2+}$-induced low-density lipoprotein oxidation than that of ascorbic acid or simvastatin. Three-month-old rabbits were fed an atherogenic diet containing 0.5% cholesterol and 10% coconut oil, while other two groups were given an atherogenic diet with intravenous injection of either simvastatin or SMBD (0.33 mg/kg/day) for 4 weeks. The concentrations of plasma cholesterol and thiobarbituric acid reactive substances were significantly decreased in SMBD groups, compared to the control group. Also, aortic lipid level in the SMBD group significantly lower than that in the control group. Furthermore, compared with the control group, the SMBD group significantly inhibited the increase of aortic intimal thickness by 36% via reducing of aortic reactive oxygen species and cyclooxygenase-2 protein levels. We conclude that raised antioxidant effect of SMBD results in significant prevention against hypercholesterolemia.
Kim, Ga Yeong,Lee, Sang Bin,Moon, Ok Kon,Kim, Ji Sung,Choi, Jung Hyun,Wang, Jung San,Park, Joo Hyun,Kim, Hong Rae,Lee, Ju Hwan,Min, Kyung Ok International Academy of Physical Therapy Research 2014 Journal of International Academy of Physical Ther Vol.5 No.2
This study investigated the effects of changes to the pulsation factor of pulsed direct currents on wound healing. Patients with a pressure ulcer at a care hospital for the elderly were randomly divided into three groups: Group 1 involved the application of $100{\mu}s$ in pulse duration, 10 ms in pulse period, 100 pps in a pulsation factor, 15 mA in pulse amplitude, and polarity red+ by using pulsed direct currents; Group 2 involved a change of pulse period to 8 ms; and Group 3 received general wound management. Although there were no statistically significant differences in the changing stages of pressure ulcers among the groups, all the groups dropped in numerical stages. In the two groups to which pulsed direct currents were applied, there was a statistically significant reduction in the stages of pressure ulcers from the initial assessment to the 12-week assessment (p<.05). Even though there were no statistically significant differences in changes to the area of pressure ulcers among the groups, a statistically significant decrease was found in pulsed direct current group 2 whose pulse period was shortened (p<.05). There was no difference in the healing rate of pressure ulcers among the groups, but it made a numerical increase in pulsed direct current group 1 and group 2 and a numerical decrease in group 3. There were no significant differences in the characteristics of those who had a full recovery among the groups. Those findings indicate that pulsed direct currents have positive effects on the wound healing of patients with a pressure ulcer and that a treatment with pulsed direct currents whose pulsation factor is raised by reducing the pulse duration is especially effective.
( Yeong Bok Song ),( Boh Kyung Kim ),( Mi Jin Choi ),( Yeong Ok Song ),( Eun Ju Cho ) 부산대학교 김치연구소 2012 김치의 과학과 기술 Vol.15 No.-
The protective effects of L-arabinose and sugar beet (SBP) on high glucose-induced oxidative stress were investigated using LLC-PK cells. Under the high glucose-induced cellular oxdative model, the treatment of 45 mM of glucose led to the decrease in cell viability and increase in lipod peroxidation_However. L-arabinose and SBP significantly inhibited the high glucose-induced cytotoxicity and lipid per-oxidation. In addition, the formation of nitric oxide(NO) was increased by the treatment of 45mM glu-cose. while the treatment of L-arabinose or SBP inhibited signigicantly the NO formation compared with high glucose-treated control. The superoxide anion production of groups treated whth L-arabinose or SBP was significantly lower than that of the control treated with high glucose. Futhermore. L-arabinose and SBP elevated the glucose uptake. resulting in lower glucose concentration compared with non-treated control. High glucose levels induced the overexpressions of bax. inducible NO synthase and cyclooxygen-ase-2. but L-arabinose or SBP treatrnent down-regulated the expressions of these genes. Arabinose and SBP also inhibited the expression of nuclear factor-kappa B induced by 45mM glucose in LLC-PK cells. In particular, arabinose exhibited stronger inhibitory activities on high glucose-induced oxdative stress than SBP did. These findings indicate that L-arabinose and SBP are promising antioxidative agents with protective activities against hyperglycemia.
Kim, Jung-Hee,Kim, Ok-Hyun,Ha, Yeong-Lae,Kim, Jeong-Ok The Korean Society of Food Science and Nutrition 2008 Preventive Nutrition and Food Science Vol.13 No.3
The enhancement of the human body fat reduction of conjugated linoleic acid (CLA) with the supplementation of $\gamma$-oryzanol (OZ) was investigated on overweight Korean women (n=51, BMI> 23). Subjects were divided into 4 groups of control, CLA, glyceride form of CLA (GCLA), and CLA plus OZ (CLA-OZ). The soft-gel capsule (500 mg) was used to deliver control (500 mg olive oil), CLA (500 mg CLA), GCLA (500 mg GCLA) and CLA-OZ (500 mg CLA plus 50 mg OZ). Three capsules were taken twice a day for 12 weeks. The CLA-OZ supplementation reduced 1.35% body fat that was 0.34% enhancement against CLA supplementation. As considered subject variations, CLA-OZ reduced body fat ranged from 7.9% to -2.7%, equivalent to 5.6 kg loss to 0.7 kg gain in body fat mass, against CLA. The CLA-OZ reduced body weight and body mass index (BMI), relative to control, but the reductions by CLA-OZ were not different from those by CLA and GCLA. All biochemical markers analyzed for safty were not significantly different within or between groups and were within the normal range. The CLA-OZ supplementation significantly reduced blood pressure, as compared to the supplementation of CLA, GCLA and control. These results suggest that OZ could be a useful ingredient to mix with CLA for the reduction of human body fat.
Linearized oncolytic adenoviral plasmid DNA delivered by bioreducible polymers
Kim, Jaesung,Kim, Pyung-Hwan,Nam, Hye Yeong,Lee, Jung-Sun,Yun, Chae-Ok,Kim, Sung Wan Elsevier 2012 Journal of controlled release Vol.158 No.3
<P><B>Abstract</B></P><P>As an effort to overcome limits of adenovirus (Ad) as a systemic delivery vector for cancer therapy, we developed a novel system using oncolytic Ad plasmid DNA with two bioreducible polymers: arginine-grafted bioreducible poly(disulfide amine)polymer (ABP) and PEG5k-conjugated ABP (ABP5k) in expectation of oncolytic effect caused by progeny viral production followed by replication. The linearized Ad DNAs for active viral replication polyplexed with each polymer were able to replicate only in human cancer cells and produce progeny viruses. The non-immunogenic polymers delivering the DNAs markedly elicited to evade the innate and adaptive immune response. The biodistribution ratio of the polyplexes administered systemically was approximately 99% decreased in liver when compared with naked Ad. Moreover, tumor-to-liver ratio of the Ad DNA delivered by ABP or ABP5k was significantly elevated at 229- or 419-fold greater than that of naked Ad, respectively. The ABP5k improved the chance of the DNA to localize within tumor versus liver with 1.8-fold increased ratio. In conclusion, the innovative and simple system for delivering oncolytic Ad plasmid DNA with the bioreducible polymers, skipping time-consuming steps such as generation and characterization of oncolytic Ad vectors, can be utilized as an alternative approach for cancer therapy.</P> <P><B>Graphical abstract</B></P><P><ce:figure id='f0005'></ce:figure></P>
Kim, Yeong Hun,Lee, Dong Woo,Ok, Kang Min American Chemical Society 2014 Inorganic Chemistry Vol.53 No.10
<P>Pure polycrystalline bulk samples and single crystals of a novel polar noncentrosymmetric (NCS) indium niobium tellurium oxide, InNb(TeO<SUB>4</SUB>)<SUB>2</SUB>, have been synthesized through solid-state reactions with In<SUB>2</SUB>O<SUB>3</SUB>, Nb<SUB>2</SUB>O<SUB>5</SUB>, and TeO<SUB>2</SUB>. InNb(TeO<SUB>4</SUB>)<SUB>2</SUB> exhibits a three-dimensional structural backbone consisting of layers of corner-shared InO<SUB>6</SUB> octahedra, layers of corner-shared NbO<SUB>6</SUB> octahedra, and chains of corner-shared TeO<SUB>4</SUB> polyhedra. The infrared spectrum shows In–O, Nb–O, and Te–O vibrations, and the UV–vis diffuse reflectance spectrum shows a band gap of 3.5 eV for the reported material. Thermal analysis indicates that InNb(TeO<SUB>4</SUB>)<SUB>2</SUB> is thermally stable to 740 °C. Powder second-order nonlinear optical (NLO) measurements reveal that InNb(TeO<SUB>4</SUB>)<SUB>2</SUB> has a strong second harmonic generation (SHG) efficiency, 100 times that of α-SiO<SUB>2</SUB>. A detailed structural examination indicates that the strong SHG is due to the combined net polarization originating from the distorted environment of second-order Jahn–Teller (SOJT) cations such as Nb<SUP>5+</SUP> and Te<SUP>4+</SUP>. Elemental analysis, the magnitude of distortion, and calculations of dipole moments for InNb(TeO<SUB>4</SUB>)<SUB>2</SUB> are also presented.</P><P>The strong second harmonic generation efficiency of InNb(TeO<SUB>4</SUB>)<SUB>2</SUB> is attributable to the combined net polarization arising from the distorted coordination environment of second-order Jahn−Teller (SOJT) distortive cations: i.e., Nb<SUP>5+</SUP> and Te<SUP>4+</SUP>.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/inocaj/2014/inocaj.2014.53.issue-10/ic5004337/production/images/medium/ic-2014-004337_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ic5004337'>ACS Electronic Supporting Info</A></P>