Clinical Usefulness of Korean Red Ginseng in Postmenopausal Women with Severe Climacteric Disturbance

Yoshihiro Kikuchi(Yoshihiro Kikuchi),Takehiko Tode(Takehiko Tode),Junko Hirata(Junko Hirata),Hideyuki Nakata(Hideyuki Nakata),Tsunekazu Kita(Tsunekazu Kita) 고려인삼학회 2003 Journal of Ginseng Research Vol.27 No.3

The aim of this study is to evaluate clinical usefulness of Korean red ginseng (RG) on various postmenopausal syndromes. Total plasminogen inhibitor-1 (tPAI-1) in peripheral blood from 9 postmenopausal women with climacteric syndromes (CS) was measured before and 3 months after treatment with daily oral administrat i on of 6g RG and that from 8 postmenopausal women without any CS was also measured as healthy controls. Blood samples were collected in the early morning on the bed-rest. Psychological conditions of postmenopausal women with CS were measured before and 3 months after treatment with RG using simplified menopausal index (SMI). In addition, OKETSU (blood stagnation) syndrome scores and KI deficiency (generalized energy stagnation) scores proposed by Terasawa et al., were recorded before and 3months after treatment with RG in postmenopausal women with CS and in healthy postmenopausal women. OKETSU syndrome scores and tPAI-1 levels in postmenopausal patients with CS were significantly (P<0.001 and<br/> P<0.01) higher than those in healthy postmenopausal women without CS. Similarly, SMI scores and KI deficiency scores in postmenopausal patients with CS were about three-fold higher than those without any CS. When RG was administered for 3 months, KI deficiency scores and OKETSU scores as well as SMI scores declined around the levels of healthy postmenopausal women. Although tPAI-1 levels significantly (P<0.05) decreased after treatment with RG, those did not reach the levels of healthy postmenopausal women. Clinical usefulness of administration of RG to postmenopausal women with CS was confirmed from evaluation not only by modern medicine but also by traditional KAMPO medicine.

Goniotrichopsis reniformis (Kajimura) Kikuchi comb. nov. (Stylonematales, Rhodophyta) from Japan

신종암,Kikuchi, Norio,West, John A.,Kajimura, Mitsuo,Shin, Jong-Ahm 한국조류학회(藻類) 2006 ALGAE Vol.21 No.2

The morphology and life history of Stylonema reniforme Kajimura (Stylonematales, Rhodophyta) from Japan were investigated and its taxonomic placement was discussed. This species has 6-30 discoid chloroplasts devoid of a pyrenoid in each cell. This is a typical feature of the genus Goniotrichopsis. The species reproduced only by monospores, which were formed by the direct transformation of the vegetative cells similar to the type species Goniotrichopsis sublittoralis Smith. Goniotrichopsis reniformis (Kajimura) Kikuchi comb. nov. was proposed. The asexual life history of the present species was completed in 3-10 weeks at 15-20°C in culture.

A 1-megadalton translocation complex containing Tic20 and Tic21 mediates chloroplast protein import at the inner envelope membrane.

Kikuchi, Shingo,Oishi, Maya,Hirabayashi, Yoshino,Lee, Dong Wook,Hwang, Inhwan,Nakai, Masato American Society of Plant Physiologists 2009 The Plant cell Vol.21 No.6

<P>Chloroplast protein import is mediated by two hetero-oligomeric protein complexes, the Tic and Toc translocons, which are located in the inner and outer envelope membranes. At the inner membrane, many Tic components have been identified and characterized, but it remains unclear how these Tic proteins are organized to form a protein-conducting channel or whether a stable Tic core complex that binds translocating preproteins exists. Here, we report the identification of a 1-megadalton (MD) translocation complex as an intermediate during protein translocation across the inner membrane in Arabidopsis thaliana and pea (Pisum sativum). This complex can be detected by blue native PAGE using the mild detergent digitonin without any chemical cross-linkers. The preprotein arrested in the 1-MD complex can be chased into its fully translocated form after a subsequent incubation. While Tic20 and Tic21 appear to be involved in the 1-MD complex, Tic110, a well-characterized Tic component, exists as a distinct entity from the complex. Several lines of evidence suggest that the 1-MD complex functions in between the Toc and Tic110-containing complexes, most likely as a protein-conducting channel at the inner envelope.</P>

전기산업의 에너지문제 해결방안

Kikuchi K 한국에너지협의회 1995 에너지協議會報 Vol.36 No.-

Pediatric hypertension based on Japanese Society of Hypertension Guidelines (JSH 2019) with actual school blood pressure screening data in Japan

Kikuchi Toru 대한소아청소년과학회 2022 Clinical and Experimental Pediatrics (CEP) Vol.65 No.6

Blood pressure (BP) in children and adolescents is associated with their growth. BP is most strongly associated with height during height gain and with degree of obesity after reaching final height. BP in childhood and adolescence is correlated with BP in adulthood. The pathophysiology of pediatric essential hypertension is associated with obesity, excess salt intake, and a low birth weight. The common causes of pediatric secondary hypertension are renal parenchymal and renovascular diseases. The significance of diagnosing pediatric hypertension involves detecting secondary hypertension and preventing organ damage due to hypertension as well as tracking essential hypertension in adulthood. Appropriate BP measurement procedures are required for diagnosing pediatric hypertension. The inflatable bladder of an appropriately sized cuff should exceed 40% of the arm circumference. BP measurements should be performed consecutively at least 3 times using an appropriately sized cuff. The diagnosis of hypertension requires that all BP values measured on 3 or more occasions be above the reference value. The criteria for pediatric hypertension are determined based on the distribution of BP in healthy children and adolescents, with values above the 95th percentile of normal representing hypertension. Japanese criteria define pediatric hypertension as ≥120/70 mmHg for preschool children, ≥130/80 mmHg for 1st–3rd graders, ≥135/80 mmHg for 4th–6th graders, ≥140/85 mmHg for 7th–9th grade boys, ≥135/80 mmHg for 7th–9th grade girls, and ≥140/85 mmHg for senior high school boys and girls. The prevalence of Japanese pediatric hypertension was 0.9% based on proper measurement protocols. The basis of managing pediatric essential hypertension is healthy lifestyle modifications. Pharmacotherapy is indicated for persistent hypertension, symptomatic hypertension, secondary hypertension, the development of target organ damage, the presence of chronic kidney disease, and diabetes mellitus. Screening for pediatric hypertension is important; therefore, BP should be routinely measured in children and adolescents.

Self-Assessment and Working time on Nut Size Distinction Skill of Marine Engineers

KIKUCHI Kazumitsu 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

A rule of thumb for marine engineers is that if a marine engineer has much experience in maintaining machines, the marine engineer can distinguish the size of the tool (spanner or wrench) required for removing machine nuts or bolts by mere observation [1]. This study investigates whether this rule of thumb is related to self-assessment and working time for the distinction of nuts. The participants in this experiment were marine engineering students without practical experience. The experiment included visual and hand conditions. The experiment place was not only a ship engine room but a training room where noise, high temperature, and the smell of fuel oil in the marine engine plant were not experienced by the students. The results showed that the number of the nuts accurately distinguished was unaffected by working hours and self-assessment of the participants who had a boarding history of 12 months on the training ship. Safe operation on marine engine plants must rely on the skills of marine engineers, such as a nut size distinction skill.

Diminished reality using semantic segmentation and generative adversarial network for landscape assessment: evaluation of image inpainting according to colour vision

Kikuchi Takuya,Fukuda Tomohiro,Yabuki Nobuyoshi 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.5

The objective of this research is to develop a method to detect and virtually remove representations of existing buildings from a video stream in real-time for the purpose of visualizing a future scenario without these buildings. This is done by using semantic segmentation, which eliminates the need to create three-dimensional models of the buildings and the surrounding scenery, and a generative adversarial network (GAN), a deep learning method for generating images. Real-time communication between devices enables users to utilize only portable devices equipped with a camera to visualize the future landscape onsite. As verification of the proposed method’s usefulness, we evaluated the complementation accuracy of the GAN and real-time performance of the entire method. The results indicated that the process is completed accurately when the area to be complemented is less than 15% of the view and that the process runs at 5.71 fps. The proposed method enables users to understand intuitively the future landscape and contributes to reducing the time and cost for building consensus.

Experimental Study On Seismic Behavior Of Masonry Walls With Column

Kikuchi, Kenji,Park, Kang-Geun 한국공간구조학회 2006 한국공간구조학회지 Vol.6 No.2

본 연구는 보강 조적벽체의 지진거동에 대한 실험적 연구로써, 기둥의 보강, 조적벽체의 보강, 횡하중 높이에 대한 역학적 특성을 분석하였다. 시험체는 구멍이 있는 콘크리트 블록으로 만들었고, 전단 스팬비, 횡하중 높이의 영향, 보강기둥 및 벽체 철근 보강비에 대한 구조적 특성을 파악할 수 있도록 하였다. 벽체의 횡력에 대한 하중점의 벽체 높이의 0.67, 1.08 및 1.1배로 하였다. 수평방향의 철근비는 0, 0.08, 0.18, 수직 방향의 철근비는 0.18, 0.36, 0.64로 하였다. In order to investigate the effect of the height of application point of lateral loads and reinforcing steel bars in walls and columns in improving the seismic behavior of confined concrete block masonry walls, an experimental research program is conducted. A total of twelve one-half scale specimens are tested under repeated lateral loads. Specimens are tested to failure with increasing maximum lateral drifts while a vertical axial load was applied and maintained constant. The specimens adopted are two-dimensional (2D) hollow concrete block masonry walls with different parameters such as shear span ratio, inflection point and percent of reinforcement in confining columns and walls. Test results obtained for each specimen include cracking patterns, load-deflection curve, and strains in reinforcement and walls in critical locations. Analysis of test data showed that above parameters generate a considerable effect on the seismic performance of confined concrete block masonry walls.

Satellite Digital Sound Broadcasting System for Mobile Users in Japan

Kikuchi, Hideo,Yamaguchi, Yoshitake 통신위성우주산업연구회 2002 Joint Conference on Satellite Communications Vol.2002 No.-

Satellite digital sound broadcasting system for mobile users using 2.6GHz radio frequency band is planned to be serviced in early 2004 in Japan. This system enables many users in mobile environment to receive a large number of various multimedia broadcasting programs such as high quality digital audio programs and MPEG-4 video programs with vehicular and very small portable receivers. In order to realize this service, a geostationary satellite with high power transponder and high gain large deployable antenna is used. Terrestrial repeaters, which retransmit broadcasting signal to the areas where the satellite signal is blocked by obstacles, are also used in urban areas. CDM (Code Division Multiplex) technique and RAKE receivers are sued for effective utilization of spectrum as well as mitigation of multipath fading. A variety of verification tests including field tests have been carried out for past several years to evaluate the system performance. In this paper, recent development status of the system is described.

Measurement of the Permeability in a Ferrite Core by Superimposing Bias Current

Kikuchi, Kousuke,Kanie, Tomohiko,Takeo, Takashi The Korean Institute of Electrical Engineers 2014 The Journal of International Council on Electrical Vol.4 No.1

In this study, we investigate measurement of the magnetic permeability in a ferrite core at RF frequencies when bias current is superimposed on an RF signal with a view to adaptively controlling performance of RF transformers using ferrite cores. A measurement arrangement used comprises a short microstrip line (MSL) circuit including a coaxial conductor (CC) structure consisting of an electrically grounded metal pipe, a center conductor and a sample between them. A bias tee network is incorporated into this MSL-CC circuit in order to superimpose direct current on an RF signal. Using this arrangement, a dependence of permeability on an amplitude of superimposed bias current was measured at frequencies of 10 MHz to 500 MHz. Reliability of the measurement results is discussed based on several experimental data, implying that the method has an accuracy less than 10 % at most of the above frequencies.