http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Izu, Hanae (검색결과 5 건)
- 무료
- 기관 내 무료
- 유료
-
-
-
유병욱,김창오,Allen Izu,Ashwani Kumar Arora,Esther Heijnen 대한감염학회 2018 Infection and Chemotherapy Vol.50 No.4
Backgroud: Influenza vaccination is recommended for adults aged ≥65 years as they are at high risk of significant morbidity and mortality. This open-label, multicenter, post-marketing surveillance study assessed the safety of the MF59-adjuvanted trivalent inactivated subunit influenza vaccine, which is marketed as FLUAD® and VANTAFLU®, in South Korean subjects aged ≥65 years. Materials and Methods: Solicited local and systemic adverse events (AEs) were collected from day 1 to 4 of the study. All unsolicited AEs and serious AEs (SAEs) were recorded from day 1 until study termination (day 29). Results: Of the 770 subjects enrolled (FLUAD®, n = 389; VANTAFLU®, n = 381), 39% overall experienced any solicited AE. Local AEs were reported by 33% of subjects overall; with the most common events being injection-site pain (30%) and tenderness (27%). Systemic AEs were reported by 19% of subjects overall with the most common events being myalgia (11%) and fatigue (8%). Conclusion: These results show that the MF59-adjuvanted influenza vaccine known as FLUAD® or VANTAFLU® had acceptable safety profiles in older adults (aged ≥65 years) in South Korea.
-
A novel HSF1-mediated death pathway that is suppressed by heat shock proteins
Hayashida, Naoki,Inouye, Sachiye,Fujimoto, Mitsuaki,Tanaka, Yasunori,Izu, Hanae,Takaki, Eiichi,Ichikawa, Hitoshi,Rho, Jaerang,Nakai, Akira Wiley (John WileySons) 2006 The EMBO journal Vol.25 No.20
<P>Heat shock response is an adoptive response to proteotoxic stress, and a major heat shock transcription factor 1 (HSF1) has been believed to protect cells from cell death by inducing heat shock proteins (Hsps) that assist protein folding and prevent protein denaturation. However, it is revealed recently that HSF1 also promotes cell death of male germ cells. Here, we found a proapoptotic Tdag51 (T-cell death associated gene 51) gene as a direct target gene of HSF1. Heat shock and other stresses induced different levels of Hsps and Tdag51, which depend on cell types. Hsps bound directly to the N-terminal pleckstrin-homology like (PHL) domain of Tdag51, and suppressed death activity of the C-terminal proline/glutamine/histidine-rich domain. Tdag51, but not major Hsps, were induced in male germ cells exposed to high temperatures. Analysis of Tdag51-null testes showed that Tdag51 played substantial roles in promoting heat shock-induced cell death in vivo. These data suggest that cell fate on proteotoxic condition is determined at least by balance between Hsp and Tdag51 levels, which are differently regulated by HSF1.</P>
-
Aninda Retno Utami Wibowo,Lina Susanti Juswara,Destri Destri,Diego Bogarín,Imam Bagus Nugroho,Izu Andry Fijridiyanto,Richa Kusuma Wati 국립중앙과학관 2025 Journal of Asia-Pacific Biodiversity Vol.18 No.2
Cymbidium (Orchidaceae: Epidendroideae) includes species of significant horticultural and ecological importance, yet limited research exists on the distribution and phylogeny of Cymbidium hartinahianum, an orchid endemic to North Sumatra, Indonesia. Here, we present the complete plastid genome of Cymbidium hartinahianum. The whole plastid genome was sequenced using the Illumina platform, followed by a pipeline for plastome assembly, annotation, and visualization. The circular genome with a length of 150,370 bp possesses the typical quadripartite structure, consisting of a large single-copy (LSC) region of 84,189 bp, a small single-copy (SSC) region of 14,611 bp, and a pair of inverted repeats (IRs) regions of 25,785 bp. The plastid genome has a total GC content of 37.0%. Annotation revealed 148 gene species, including 96 protein-coding genes, 52 transfer RNA, and four ribosomal RNA (rRNA) genes. Bayesian and maximum likelihood phylogenetic analyses based on 52 plastomes confirmed that C. hartinahianum is sister to C. floribundum and belongs to the Cymbidium section Floribundum. This newly sequenced plastome data will be valuable for future Cymbidium phylogenomic and biogeographical studies. It also provides new molecular data for conservation efforts, including DNA barcoding to help prevent the illegal trade of this endangered orchid.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
