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        A Case Report of Partial Nephrectomy of Mucinous Cystadenocarcinoma in Kidney and Its Literature Review

        김성한,Heong Dong Yuk,박원서,김선호,정재영,서호경,이강현,정진수 대한암학회 2016 Cancer Research and Treatment Vol.48 No.2

        Mucinous cystadenocarcinoma (MC) of the kidney is a rare epithelial tumor originating from the renal pelvic urothelium and few study cases have been reported. Because of the rarity of these tumors and their unknown histogenesis, its diagnosis is difficult until surgical exploration. We report here on a 55-year-old man referred to the urology department from the hepatology department because of a cystic renal mass measuring approximately 5 cm in size, which was detected incidentally under ultrasonography during the routine examination of liver. The renal mass was finally diagnosed as MC originating from kidney after partial nephrectomy and the patient still showed no evidence of recurrence until 12 months postoperatively. This is the first report on a case of renal MC in a patient who underwent partial nephrectomy. The aim of this report is to present our unusual case of MC and also review the previous literature on the pathological and radiological aspects of MC of kidney.

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        Predictive Factors for Maximal Size Reduction of Renal Target Lesion in Patients with Metastatic Renal Cell Carcinoma Receiving Targeted Therapies

        Sung Han Kim,In-Chang Cho,Sun Ho Kim,Jae Young Joung,Ho Kyung Seo,Kang Hyun Lee,Heong Dong Yuk,Jinsoo Chung 대한비뇨기종양학회 2014 대한비뇨기종양학회지 Vol.12 No.3

        Purpose: To evaluate the renal target lesion response in metastatic renal cell carcinoma (mRCC) patients treated with targeted therapy (TT) and to determine predictive factors for maximal tumor size reduction. Materials and Methods: We reviewed the clinical and radiographic data of 43 mRCC patients with 47 primary renal target legions (RTL) treated with at least two cycles of TT between 2007 and 2011. RTL response was evaluated using Response Evaluation Criteria Solid Tumors (RECIST) v.1.1. The significant predictive factors corresponding to the best response of RTL size reduction between the size reduction group (RG, n=36) and the non-reduction group (NRG, n=11) was statistically analyzed. Results: During a median follow-up period of 7.4 months, median RTL size was 82mm and its mean change in size was -7.35mm. Multivariate analysis showed that body surface area (BSA) (p=0.016) and RTL size (p=0.024) were independently significant in shorter time to maximize size reduction. After classification of four RTL groups according to the combination of BSA of 1.62㎡ and RTL size of 82mm, significant differences in time to maximal size reduction were observed (log rank, p=0.009). Conclusions: BSA and RTL size were the best predictive factors for reduction of RTL size with time for maximal tumor response during TT.

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