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Zhao Yang Dong,Chee Khiang Pang,Pei Zhang 대한전기학회 2005 International Journal of Control, Automation, and Vol.3 No.2
Deregulations and market practices in power industry have brought great challenges to the system planning area. In particular, they introduce a variety of uncertainties to system planning. New techniques are required to cope with such uncertainties. As a promising approach, probabilistic methods are attracting more and more attentions by system planners. In small signal stability analysis, generation control parameters play an important role in determining the stability margin. The objective of this paper is to investigate power system state matrix sensitivity characteristics with respect to system parameter uncertainties with analytical and numerical approaches and to identify those parameters have great impact on system eigenvalues, therefore, the system stability properties. Those identified parameter variations need to be investigated with priority. The results can be used to help Regional Transmission Organizations (RTOs) and Independent System Operators (ISOs) perform planning studies under the open access environment.
Anti-proliferation Effects of Interferon-gamma on Gastric Cancer Cells
Zhao, Ying-Hui,Wang, Tao,Yu, Guang-Fu,Zhuang, Dong-Ming,Zhang, Zhong,Zhang, Hong-Xin,Zhao, Da-Peng,Yu, Ai-Lian Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9
IFN-${\gamma}$ plays an indirect anti-cancer role through the immune system but may have direct negative effects on cancer cells. It regulates the viability of gastric cancer cells, so we examined whether it affects their proliferation and how that might be brought about. We exposed AGS, HGC-27 and GES-1 gastric cancer cell lines to IFN-${\gamma}$ and found significantly reduced colony formation ability. Flow cytometry revealed no effect of IFN-${\gamma}$ on apoptosis of cell lines and no effect on cell aging as assessed by ${\beta}$-gal staining. Microarray assay revealed that IFN-${\gamma}$ changed the mRNA expression of genes related to the cell cycle and cell proliferation and migration, as well as chemokines and chemokine receptors, and immunity-related genes. Finally, flow cytometry revealed that IFN-${\gamma}$ arrested the cells in the G1/S phase. IFN-${\gamma}$ may slow proliferation of some gastric cancer cells by affecting the cell cycle to play a negative role in the development of gastric cancer.
Investigation of Strain Measurements using Digital Image Correlation with a Finite Element Method
Zhao Jian,Zhao Dong 한국광학회 2013 Current Optics and Photonics Vol.17 No.5
This article proposes a digital image correlation (DIC) strain measurement method based on a finite element (FE) algorithm. A two-step digital image correlation is presented. In the first step, the gradientbased subpixels technique is used to search the displacements of a region of interest of the specimen,and then the strain fields are obtained by utilizing the finite element method in the second step. Both simulation and experiment processing, including tensile strain deformation, show that the proposed method can achieve nearly the same accuracy as the cubic spline interpolation method in most cases and higher accuracy in some cases, such as the simulations of uniaxial tension with and without noise. The results show that it also has a good noise-robustness. Finally, this method is used in the uniaxial tensile testing for Dahurian Larch wood specimens with or without a hole, and the obtained strain values are close to the results which were obtained from the strain gauge and the cubic spline interpolation method.
Assessment of Gradient-based Digital Speckle Correlation Measurement Errors
Zhao Jian,Zhao Dong,Zhang Zhe 한국광학회 2012 Current Optics and Photonics Vol.16 No.4
The optical method Digital Speckle Correlation Measurement (DSCM) has been extensively applied due its capability to measure the entire displacement field over a body surface. A formula of displacement measurement errors by the gradient-based DSCM method was derived. The errors were found to explicitly relate to the image grayscale errors consisting of sub-pixel interpolation algorithm errors, image noise,and subset deformation mismatch at each point of the subset. A power-law dependence of the standard deviation of displacement measurement errors on the subset size was established when the subset deformation was rigid body translation and random image noise was dominant and it was confirmed by both the numerical and experimental results. In a gradient-based algorithm the basic assumption is rigid body translation of the interrogated subsets, however, this is in contradiction to the real circumstances where strains exist. Numerical and experimental results also indicated that, subset shape function mismatch was dominant when the order of the assumed subset shape function was lower than that of the actual subset deformation field and the power-law dependence clearly broke down. The power-law relationship further leads to a simple criterion for choosing a suitable subset size, image quality, sub-pixel algorithm,and subset shape function for DSCM.
Effects of Zinc on the Activity and Conformational Changes of Arginine Kinase and Its Intermediate
( Zhao Dong Du ),( Xi Cheng Wang ) 생화학분자생물학회 2003 BMB Reports Vol.36 No.4
The effects of zinc on arginine kinase and its collapsed-state intermediate were studied. Both arginine kinase and the collapsed-state intermediate were inactivated in the presence of zinc, following a biphasic kinetic course. The corresponding apparent rate constants of inactivation at different zinc concentrations and conformational changes in the presence of 0.5 mM zinc were obtained. The conformational changes of arginine kinase and the collapsed-state intermediate were followed by fluorescence spectra and circular dichroism spectra. Comparison of the results for arginine kinase and the collapsed-state intermediate showed that the collapsed-state intermediate was more susceptible to zinc, which indicated that the collapsed-state intermediate was more flexible and unstable than arginine kinase. The special structure of arginine kinase might explain these diverse phenomena.
Dong-Xia Zhao,Jun-Min Wang,Ya-Ping Guo 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.1
This paper addresses the exponential stability for an interconnected system of an nth-order ODE systemwith the input governed by the Dirichlet boundary of a heat equation, and conversely, the output of the ODE isfluxed into the heat equation. The semigroup approach is adopted to show that the system operator is well-posed. We establish the exponential stability of the system by Riesz basis method. Furthermore, with MATLAB software,some numerical simulations are presented to show the effectiveness of the interconnection between the heat PDEand ODE systems.
Dong-xia Zhao,Dong-xia Fan,Ya-ping Guo 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.8
In this paper, the well-posedness and stability of a 1-d 2×2 hyperbolic system under proportional feedback control is addressed. The semigroup approach and norm equivalence theorem is adopted to obtain the explicit dissipative condition for control parameters. The asymptotic spectral analysis of the system is presented. It is shown that the real part of the eigenvalues goes to some negative constant as the modulus of eigenvalues goes to +∞. Moreover, we find that there is a group of generalized eigenfunctions which forms a Riesz basis of the Hilbert state space. Hence, the spectrum determined growth condition holds, and then the exponential stability is established.
Dong Zhao,Chen Yao 대한심장학회 2022 Korean Circulation Journal Vol.52 No.6
Pragmatic clinical studies, an emerging clinical research discipline, include a wide range of studies that are largely embedded with routine clinical practice and aim to evaluate the comparative effectiveness and safety of different clinical intervention strategies. Increased availability and quality of electronic medical/health records drives the development of pragmatic clinical studies. In this review, we describe evolution of the conceptual framework of pragmatic clinical studies and share perspectives on the importance of pragmatic clinical studies in evidence-based practice for cardiovascular diseases, as a complement to conventional randomized controlled trials. We also highlight specific needs of pragmatic clinical studies in improving evidence-based practice for cardiovascular disease in Asian countries. The main challenges of pragmatic clinical studies are discussed briefly in this review.