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Kim, Byunghoon,An, Jungkwen,Yu, Yongli,Cheng, Ya,Xu, Zhizhan,Kim, Dong Eon The Optical Society 2008 Optics express Vol.16 No.14
<P>The effect of the mixing of pulsed two color fields on the generation of an isolated attosecond pulse has been systematically investigated. One main color is 800 nm and the other color (or secondary color) is varied from 1.2 to 2.4 microm. This work shows that the continuum length behaves in a similar way to the behavior of the difference in the square of the amplitude of the strongest and next strongest cycle. As the mixing ratio is increased, the optimal wavelength for the extended continuum shifts toward shorter wavelength side. There is a certain mixing ratio of intensities at which the continuum length bifurcates, i.e., the existence of two optimal wavelengths. As the mixing ratio is further increased, each branch bifurcates again into two sub-branches. This 2D map analysis of the mixing ratio and the wavelength of the secondary field easily allows one to select a proper wavelength and the mixing ratio for a given pulse duration of the primary field. The study shows that an isolated sub-100 attosecond pulse can be generated mixing an 11 fs full-width-half-maximum (FWHM), 800 laser pulse with an 1840 nm FWHM pulse. Furthermore the result reveals that a 33 fs FWHM, 800 nm pulse can produce an isolated pulse below 200 as, when properly mixed.</P>
Park, Bernie Byunghoon,Lee, NaHye,Kim, YunHye,Jae, YoonGyu,Choi, Seunghyun,Kang, NaNa,Hong, Yu Ri,Ok, Kiwon,Cho, Jeonghee,Jeon, Young Ho,Lee, Eun Hee,Byun, Youngjoo,Koo, JaeHyung Wiley (John WileySons) 2017 CHEMMEDCHEM Vol.12 No.7
<P>Identification of potent agonists of odorant receptors (ORs), a major class of Gprotein-coupled receptors, remains challenging due to complex receptor-ligand interactions. ORs are present in both olfactory and non-chemosensory tissues, indicating roles beyond odor detection that may include modulating physiological functions in non-olfactory tissues. Selective and potent agonists specific for particular ORs can be used to investigate physiological functions of ORs in non-chemosensory tissues. In this study, we designed and synthesized novel synthetic dehydroacetic acid analogues as agonists of odorant receptor 895 (Olfr895) expressed in bladder. Among the synthesized analogues, (E)-3-((E)-1-hydroxy-3-(piperidin-1-yl)allylidene)-6-methyl-2H-pyran-2,4(3H)-dione (10) exhibited extremely high agonistic activity for Olfr895 in Dual-Glo luciferase reporter (EC50=9nm), Ca2+ imaging, and chemotactic migration assays. Molecular docking and site-directed mutagenesis studies suggested that a combination of hydrophilic and hydrophobic interactions is central to the selective and specific binding of 10 to Olfr895. The design of agonists armed with both hydrophilic and hydrophobic portions could therefore lead to highly potent and selective ligands for ectopic ORs.</P>
Prediction of Corporate Bankruptcy with Machine Learning
Haein Lee,Byunghoon Yu,Jang Hyun Kim,Heungju Park 한국재무학회 2022 한국재무학회 학술대회 Vol.2022 No.11
This study examines the predictability of various machine learning and deep learning models in corporate default forecasts. Using a sample of U.S. corporate defaults over the period of 1963-2020, we find Ensemble classifier and Bi-LSTM classifier forecast the corporate bankruptcy better than other models and the predictability of the Ensemble classifier is more stable in year-to-year variability. Further, machine learning models outperform deep learning models in high yield grade samples, while deep learning models performs better than machine learning models in investment grade samples.
관성항법장치를 이용한 K2전차 전차포 자세측정 방법 및 명중률에 미치는 영향에 대한 연구
김성호,김건국,권혁민,유석진,박병훈,이병길,김의환,Kim, Sungho,Kim, GunKook,Kwon, Hyukmin,Yu, Sukjin,Park, Byunghoon,Lee, Byunggil,Kim, Euiwhan 한국군사과학기술학회 2016 한국군사과학기술학회지 Vol.19 No.2
In the original design of K2 tank the Vertical Sensor Unit(VSU) was mounted to measure the attitude of the main gun to enhance the hit probability. In this research, as a part of efforts to reduce the cost of K2, it was theoretically simulated and evaluated to use the data from Inertial Navigation System(INS) for the calculation of the gun attitude instead of the direct measurement using VSU. It was found that the negative effect of INS approach is negligible and the elimination of VSU is technically possible and beneficial to the system.