서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line

Young-Joo Hur,Young-Ki Kim,Hyun-Ho Kwak,Gyoo-Cheon Kim,Seung-Eun Lee,In-Ryoung Kim,Chul-Hoon Kim1,Bong-Soo Park 대한해부학회 2009 Anatomy & Cell Biology Vol.42 No.2

Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce apoptosis in a few cancer cells in vitro. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of cotreatment with a natural product, CGM and a CDCA derivative, HS-1200 on G361 human melanoma cells. To investigate whether the co-treatment of CGM and HS-1200 compared with each single treatment efficiently reduced the viability of G361 cells, MTT assay was conducted. To investigate augmentation of apoptosis in G631 cells co-treated with CGM and HS-1200, DNA electrophoresis, Hoechst staining, proteasome activity assay, flow cytometry, Westen blot analyses, immunofluorescent staining and confocal microscopy were performed. In this study, G361 cells co-treated with CGM and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, DNA fragmentation, the reduction of MMP and proteasome activity, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF and DFF40 (CAD) onto nuclei, activation of caspase-9, caspase-3, PARP and DFF45 (ICAD), and up-regulation of Bax whereas each single treated G361 cells did not. Although the single treatment of 40 μg/mL CGM or 25 μM HS-1200 for 24 hrs did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore, combination therapy of CGM and HS-1200 could be considered, in the future, as an alternative therapeutic strategy for human melanoma.

急性特發性心囊炎의 1例

金星潤,孫宜錫,李禎均,許鳳烈,咸駿洙,金鮮宙 대한의학협회 1977 대한의학협회지 Vol.20 No.9

최근의 대학 교양영어 교재에 대한 어 · 문학적 고찰

김봉주,신성철,유재익 충남대학교 인문과학연구소 1974 인문학연구 Vol.1 No.1

It is true that the general English textbooks which the Korean colleges and universities use recently have considerably improved for the past thirty years; but still, some of them are edited and published without any good principle. To reflect our attitude toward the compilation of textbooks, we review here some of the readers and laboratory workbooks which are used recently at the ten institutes we have chosen at random. Ten kinds of textbooks that we could collect are for reading, and eight for laboratory. The purpose of learning general English in college is to attain a basic knowledge of English that educated men should have in common and to foster the ability to comprehend the students major textbooks. Someone emphasize hearing or speaking rather than reading English. But in Korea we can not help emphasizing reading. If possible reading and speaking are expected to be well-balanced in learning. To fulfil the above mentioned purpose a suitable textbook of English for college students must be considered from the linguistic and literary point of view. So in this paper we investigate each of the ten colleges' books and found out the following characteristics : (1) The colleges are trying to pay attention to the compilation of better textbooks. (2) The simple style of the books is changing into a comparatively complex one. (3) They show a tendency to avoid taking special literary works only and to include some essays or many varieties of writings. (4) They put emphasis not only upon written English but also upon spoken English. (5) Most of the lessons in those books possess cultural and practical value. (6) Most of the lessons have remarkable notes and exercises. We would like to make following suggestions: (1) Compilers should study every unit more carefully. (2) Textbooks should be systematical. (3) The content of a book had better be a such one that students are interested in. (4) Archaic passages should be replaced with fresh ones. (5) Many varieties of contents should be taken. (6) Compilers and publishers must be conscientious.

기의 과학적 연구

김봉주 한국정신과학학회 1999 韓國精神科學學會誌 Vol.3 No.2

동양철학자들은 일찍부터 우주만물의 궁극적 구생원료는 기라는 견해를 견지해왔다. 그럼에도 서양과학자들은 아직껏 그 설을 쾌히 받아들이지 않고 있는 실정이다. 이에 기가 우주구성의 궁극적 질료로서 그것이 어떻게 만물을 생성하는가를 과학적으로 밝히고자 한다. Oriental philosophers have long before had a view that an ultimate an material of which the universe is composed is 'ki'. Western scientists, however, have never accepted this view yet. So here we scientifically examine theory of 'ki' I. e an ultimate energy-material(UEM), and identify how it generates all things in me universe.

意味生成에 關한 硏究

金鳳柱 충남대학교 인문과학연구소 1975 인문학연구 Vol.2 No.1

This study attempts to characterize how the meaning of a word may undergo change or generate various meamings in contexts, but still retain some features or vestige of its original meaning. For instance, man, which means a general person in the lexicon, has become specialized as paraphrased in the following classical examples: My man (=husband) is not at home. They are the King's men (=servants), He is an Oxfordman(=student). Or a word may acquire a figurative meaning as man in She is a man (=manly), eye in the eye of a needle, or hand in the hands of a clock. Thus primary meaning is taken here as the material with which the various peripheral meanings are generated, either connotatively or denotatively. For example, deer, whose meaning has been tremendously specialized, since Old English times, still retains the meaning 'animateness', the various tables in the contexts such as the table for breakfast, the time table, and the table of contents have the meaning 'flatness'. The polysemical use of a word comes from association; we associate cattle with cow, bull, horn, rumination, slow, dull, etc., as exemplified in Tom's cattle are bullfighters, My reminiscence of her is always of cattle, or You are cattle! The field of association is a device for generating meaning. Compounding or making phrases or wordgroups, is another device for it, e. g., lion-hunting, blood-let, kill-joy, dark-blue, whitewash, noble man, take part in, a very pretty girl, his safe arrival. These devices make it possible for us to generate countless meanings with a small number of symbols(words). Therefore, it is assumed here that some words have a more powerful generative capacity than others, because they are basic in terms of structural importance, i. e., semantic field and frequency. C. K. Ogden's Basic English, which is widely regarded as basic in this sense, is used as the source materials for this study. And in redefining or rephrasing, I selected 142 words as sememes from his 850 vocabulary items, and then tested their reproductive (generative) capacity by using the 142 words.

흰쥐 중추신경계내 난소로 투사하는 미주신경로에 관한 연구

김명주,장명세,고미희,노해숙,조해영,오문유,이봉희 濟州大學校 基礎科學硏究所 2001 基礎科學硏究 Vol.14 No.1

본 실험은 부교감신경의 하나인 미주신경이 난소를 지배하는 신경으로 관여하고 있는지를 pseudorabies 바이러스를 이용하여 난소신경로와 난소주사후 미주신경절단을 통하여 조사한 연구 보고이다. 이를 위하여 Sprague Dawley계 암흰쥐를 대상으로 pseudorabies 바이러스를 난소에 주사한 무리와 난소 주사후 미주신경을 절단한 무리에서 뇌를 적출하여 pseudorabies 바이러스에 대한 면역조직화학 염색을 시행하여 비교하였다. 본 실험결과 미주신경 중추신경로내의 상위신경핵들이 pseudorabied 바이러스에 대하여 양성반응이 줄어들었거나 관찰되지 않는 차이를 보였다. 즉 적색핵, 종말판혈관기관, 줄무늬체, 침상핵과 이마엽겉질은 부분적으로 난소의 미주신경로에 관여하고 있으며 미주신경등쪽핵, 고립로핵, 최후영역, 청색반점, 팔옆핵, 코리케퓨즈핵, 흑색질 및 시각교차위핵은 양성반응이 관찰되지 않아 미주신경으로 투사하는 부교감신경핵으로 조사되었다. The mammalian ovary has been known as receiving its innervation by sympathetic and sensory neurons of the peripheral nervous system from the brain. Recently, there were several functional reports that the vagus nerves were also regulating the ovarian function, but the vagus nerve had not been identified by clear morphological evidence. A viral transneuronal tracing technique has been used to demonstrate the morphological evidence for the central vagal involvement in ovarian innervation in brain areas. Bartha strain of pseudorabies virus injection was made into the ovary of Sprague Dawley rats. In experimental group, the vagus nerve of the same injection side was removed right after ovarian injection. At five days after initial injection, all the rats were sacrificed and brains were processed for immunohistochemistry. Several central nuclei including hypothalamic paraventricular nucleus showed strong bilateral positive labelings after unilateral injection in control rats, but the positive labelings were disappeared or decreased in several hypothalamic nuclei and nuclei of the vagus nerve. I n conclusion, these results provide the morphological evidence that vagus nerve has neural connection to ovary and by which the central nervous system may maintains the state of ovulation and reproduction as a possible parasympathetic routes in mammals.

국제어 제정의 방법과 실제

김봉주 충남대학교 어학연구소 1992 언어 Vol.13 No.-

쇼핑호스트에 대한 의사인간관계가 홈쇼핑 TV에 대한 태도 및 구매의도에 미치는 영향 : 지각된 위험과 지각된 혜택의 매개효과를 중심으로

주지혁,최명일,김봉철 한국방송광고공사 2008 광고연구 Vol.0 No.80

Home-shopping in cable TV is considered as one of the important channels by innovative changes for the shopping. In this process, shopping hosts take a great portion, but they are not weighted in other studies. This study explores various emotions for the shopping hosts in the field of parasocial interaction and examines how those emotions affect to purchase intention. Also, the study can see over how perceived risk, perceived benefit, and attitude for the CATV home-shopping have an impact on the purchase intention. In the result, as parasocial interaction with shopping-hosts would grow, perceived risk for home-shopping is reduced, meanwhile perceived benefit is grown. Perceived risk can mediate purchase intention, and perceived benefit also can moderate attitude for homeshopping and purchase intention. It could mean that consumers can have positive image for CATV home-shopping under the conditions that parasocial interaction with shopping-hosts would be grown. The result can show that CATV home-shopping should attempt to establish parasocial interaction in order to take upper hands against open markets and internet shopping malls.

유리피판을 이용한 하인두-식도 재건 치험례

봉정표,정윤규,이훈범,김주봉,이재화,나동균,김석원 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.6

Hypopharyngo-esophageal cancer is usually found at late stage. Its main treatment is surgical intervention and it often requires radical resection. Reconstruction of the hypopharyngo-esophageal defect after the resection of carcinomas of the hypopharynx and the cervical esophagus has traditionally been carried out with deltopectoral or musculocutaneous flap. Another approach is to reconstruct the defect with the colon or stomach. Recent advances in microvascular surgical techniques have resulted in one stage reconstruction with free flap. Both jejunal free flap and radial forearm free flap is a good alternative for the reconstruction of hypopharyngo-esophageal defect. Six cases of the radial forearm flap and nine cases of the jejunal flap were used to reconstructed the hypopharyngo-esophageal defect in 15 patients. In jejunal free flap, upper margin was reconstructed with end to side anastomosis and lower margin with end to end anastomosis. In radial forearm free flap, we used trapezoid shaped flap and tubed by complete or partial tubing according to the condition of the defects. Stricture and fistula are troublesome complications. The complications were peritonitis(n=1) and fistula(n=1). We concluded that both forearm and jejunal free flap is a useful alternative in reconstruction of hypopharynx and cervical esophagus.