서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line

Young-Joo Hur,Young-Ki Kim,Hyun-Ho Kwak,Gyoo-Cheon Kim,Seung-Eun Lee,In-Ryoung Kim,Chul-Hoon Kim1,Bong-Soo Park 대한해부학회 2009 Anatomy & Cell Biology Vol.42 No.2

Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce apoptosis in a few cancer cells in vitro. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of cotreatment with a natural product, CGM and a CDCA derivative, HS-1200 on G361 human melanoma cells. To investigate whether the co-treatment of CGM and HS-1200 compared with each single treatment efficiently reduced the viability of G361 cells, MTT assay was conducted. To investigate augmentation of apoptosis in G631 cells co-treated with CGM and HS-1200, DNA electrophoresis, Hoechst staining, proteasome activity assay, flow cytometry, Westen blot analyses, immunofluorescent staining and confocal microscopy were performed. In this study, G361 cells co-treated with CGM and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, DNA fragmentation, the reduction of MMP and proteasome activity, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF and DFF40 (CAD) onto nuclei, activation of caspase-9, caspase-3, PARP and DFF45 (ICAD), and up-regulation of Bax whereas each single treated G361 cells did not. Although the single treatment of 40 μg/mL CGM or 25 μM HS-1200 for 24 hrs did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore, combination therapy of CGM and HS-1200 could be considered, in the future, as an alternative therapeutic strategy for human melanoma.

lim Sin=1 의 증명에 관한 연구

金柱鳳 淸州敎育大學校 1983 論文集 Vol.20 No.-

사람 태아 췌장 발생에 관한 조직학적 연구

김동주,이원복,라봉진 중앙대학교 의과대학 의과학연구소 1981 中央醫大誌 Vol.6 No.4

The pancreas of human fetuses aged from 6 to 38 weeks were observed for the developmental study ,of the primitive pancreatic ducts, acini, islets of Langerhans, the time of appearance, and morphology of the islet cells. 1. The fusion of the ventral and dorsal pancreata has been encountered on the sixth week of fetal life as an organ containing the primitive pancreatic ducts surrounded by a large amount of loose con nective tissue. The epithelial cells of the ducts are abundant in glycogen. They fused with the neighboring cells with junctional complexes at free surface and with desmosoms at some place deeper into the intercellular space, and the other portion of the intercellular space is slightly widened. The ducts branch to form the lobules and then the lobes in accordance with the increase of fetal age. 2. In the pancreas of the twelfth week of fetus the primitive acinar cells, having many oval or fusiform granules and lamellated granular endoplasmic reticulum, appear around the terminal portion of the primitive pancratic duct and show rapid growth thereafter. 3. The endocrine cells appear in the order of alpha, delta, and beta cells, on the eighth and half, twelfth, and thirteenth week of fetuses, respectively. They proliferate to form the islets which have alpha and delta cells as the major types of the islets, and then become gradually degenerate. New islets which look like the adult islets, and have beta cells as the major type, begin to appear. The alpha cells have small, round granules and the beta cells have granules with crystalline structure as a core.

최근의 대학 교양영어 교재에 대한 어 · 문학적 고찰

김봉주,신성철,유재익 충남대학교 인문과학연구소 1974 인문학연구 Vol.1 No.1

It is true that the general English textbooks which the Korean colleges and universities use recently have considerably improved for the past thirty years; but still, some of them are edited and published without any good principle. To reflect our attitude toward the compilation of textbooks, we review here some of the readers and laboratory workbooks which are used recently at the ten institutes we have chosen at random. Ten kinds of textbooks that we could collect are for reading, and eight for laboratory. The purpose of learning general English in college is to attain a basic knowledge of English that educated men should have in common and to foster the ability to comprehend the students major textbooks. Someone emphasize hearing or speaking rather than reading English. But in Korea we can not help emphasizing reading. If possible reading and speaking are expected to be well-balanced in learning. To fulfil the above mentioned purpose a suitable textbook of English for college students must be considered from the linguistic and literary point of view. So in this paper we investigate each of the ten colleges' books and found out the following characteristics : (1) The colleges are trying to pay attention to the compilation of better textbooks. (2) The simple style of the books is changing into a comparatively complex one. (3) They show a tendency to avoid taking special literary works only and to include some essays or many varieties of writings. (4) They put emphasis not only upon written English but also upon spoken English. (5) Most of the lessons in those books possess cultural and practical value. (6) Most of the lessons have remarkable notes and exercises. We would like to make following suggestions: (1) Compilers should study every unit more carefully. (2) Textbooks should be systematical. (3) The content of a book had better be a such one that students are interested in. (4) Archaic passages should be replaced with fresh ones. (5) Many varieties of contents should be taken. (6) Compilers and publishers must be conscientious.

여가스포츠 참여에 따른 주부의 건강증진 생활방식의 변화

김은주,권봉안 韓國體育大學校附屬 體育科學硏究所 1998 韓國體育大學校附屬 體育科學硏究所論文集 Vol.17 No.1

The propose of this study was to indentify the relationship between housewives of leisure activity and life pattern for the improvement of health. The subjects of this study were selected using the random cluster sampling method. To achieve this purpose, people together who live in Seoul as monitors, then to be samples who goes to gym which is placed Kyung-gi area. We selected two of gyms in each areas randomly totally 8 gyms, and then considered the rate of participants per unparticipants to make 480 samples from collecting 60 samples from each areas. We obtained the knowledge form rolling paper that ask whether being active in sports or not and how many times being active in sprots and measured the life pattern for being healthy with the rolling paper which is developed by Walken, Sechrist and Pender(1987)and updated by Seo, Yun-Ok. To statistical methods utilized in this study for analyzing the collected data were reliability analysis, descriptive statistics, analysis of covariance, multiple classification analysis and standard multiple regression analysis. From the analyses of data, this study reached the following conclusion: Firstly, there are partially differences between the leisure activities of housewives and the life pattern for being healthy which is by characteristic variable factors in statistics of population. There are no difference of degree of self-achievement and people relationship in each ears of age. However, the intensity of responsibility for health is high in 50 year of old the difference between the practice and nutrition is high in 40 year of old, and the treatment of stress is high in 30 year of old. The difference of life pattern for being healthy by the existence of job effects only practice and nutrition and the difference of life pattern for being healthy by scholarship treat self-achievement and health-responsibility highly. The difference by religion shows the person who have own religion have stronger responsibility than the person who do not have. The rage of self-achievement, health responsibility, practice and nutrition is high in high-income and the person who gas many number of children shows high health responsibility, people-to-people relationship, self-achievement, practice and nutrition. Secondly, there os a difference of life style for health-improvement from housewife's participation of leisure sports. The desire of self-achievement of participant is higher than unparticipant, but it is not affect to participant leisure sports. Therefore as a result of above, as much as the housewives attention in leisure sport activities, the degree of nutrition.

意味生成에 關한 硏究

金鳳柱 충남대학교 인문과학연구소 1975 인문학연구 Vol.2 No.1

This study attempts to characterize how the meaning of a word may undergo change or generate various meamings in contexts, but still retain some features or vestige of its original meaning. For instance, man, which means a general person in the lexicon, has become specialized as paraphrased in the following classical examples: My man (=husband) is not at home. They are the King's men (=servants), He is an Oxfordman(=student). Or a word may acquire a figurative meaning as man in She is a man (=manly), eye in the eye of a needle, or hand in the hands of a clock. Thus primary meaning is taken here as the material with which the various peripheral meanings are generated, either connotatively or denotatively. For example, deer, whose meaning has been tremendously specialized, since Old English times, still retains the meaning 'animateness', the various tables in the contexts such as the table for breakfast, the time table, and the table of contents have the meaning 'flatness'. The polysemical use of a word comes from association; we associate cattle with cow, bull, horn, rumination, slow, dull, etc., as exemplified in Tom's cattle are bullfighters, My reminiscence of her is always of cattle, or You are cattle! The field of association is a device for generating meaning. Compounding or making phrases or wordgroups, is another device for it, e. g., lion-hunting, blood-let, kill-joy, dark-blue, whitewash, noble man, take part in, a very pretty girl, his safe arrival. These devices make it possible for us to generate countless meanings with a small number of symbols(words). Therefore, it is assumed here that some words have a more powerful generative capacity than others, because they are basic in terms of structural importance, i. e., semantic field and frequency. C. K. Ogden's Basic English, which is widely regarded as basic in this sense, is used as the source materials for this study. And in redefining or rephrasing, I selected 142 words as sememes from his 850 vocabulary items, and then tested their reproductive (generative) capacity by using the 142 words.

미적분 개념 형성과 Mathematica의 이용(Ⅰ)

김병무,김주봉 淸州敎育大學校 科學敎育硏究所 1998 科學과 數學敎育論文集 Vol.19 No.-

With the Mathematica, mathematics teaching is generalized in Calculus and the instruction using Mathematica to get the conceptual understanding is effective and through the dissertations of U.S.A. university we got many study results which are good for teaching and learning Calculus from 1993 to now. In this paper, concretely we show the geometrical illustration of limit, animation of a secant line approaching the tangent line and graphing with y, y' and y'' which can help to get the conceptual understanding using the Mathematica. The sooner we use the Mathematica in my university, the better we get the effectiveness of teaching Calculus.

S 環境에서 地圖 資料의 活用

金熙載,金捧柱 慶星大學校 1994 論文集 Vol.15 No.2

The purpose of this paper is a construction about 2 dimensional array with a line data set by selecting co-ordinates data set from given PCX file for map. The map graph is generated from constructed array and is reconform to user function on S envirnment.

潛在意味

金鳳柱 충남대학교 어학연구소 1980 언어 Vol.1 No.-