Mitochondrial DNA Diversity and Origin of Red Chittagong Cattle

Bhuiyan, M.S.A.,Bhuiyan, A.K.F.H.,Yoon, D.H.,Jeon, J.T.,Park, C.S.,Lee, J.H. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.10

To determine the origin and genetic diversity of Red Chittagong (RC) cattle in Bangladesh, we analyzed mitochondrial DNA displacement loop (D-loop) sequences of 48 samples along with 22 previously published sequences from Bos indicus and Bos taurus breeds. Twenty five haplotypes were identified in RC cattle that were defined by 44 polymorphic sites and nucleotide diversity was $0.0055{\pm}0.0026$. The estimated sequence divergence times between RC and other zebu cattle breeds studied ranged between 22,700-26,900 years before present (YBP) which, it is suggested, predate domestication of RC cattle. Furthermore, it is assumed that introgressions have occurred in this breed mainly from Indian zebu breeds in the recent millennia. The phylogenetic studies showed RC cattle clustered with Bos indicus lineage with two distinct haplogroups representing high genetic variability of this breed. These findings can be used for designing proper breeding and conservation strategies for RC cattle in Bangladesh.

Mitochondrial DNA Diversity and Origin of Red Chittagong Cattle

Bhuiyan, M.S.A.,Bhuiyan, A.K.F.H.,Yoon, D.H.,Jeon, J.T.,Park, C.S.,Lee, J.H. 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

To determine the origin and genetic diversity of Red Chittagong (RC) cattle in Bangladesh, we analyzed mitochondrial DNA displacement loop (D-loop) sequences of 48 samples along with 22 previously published sequences from Bos indicus and Bos taurus breeds. Twenty five haplotypes were identified in RC cattle that were defined by 44 polymorphic sites and nucleotide diversity was 0.0055±0.0026. The estimated sequence divergence times between RC and other zebu cattle breeds studied ranged between 22,700-26,900 years before present (YBP) which, it is suggested, predate domestication of RC cattle. Furthermore, it is assumed that introgressions have occurred in this breed mainly from Indian zebu breeds in the recent millennia. The phylogenetic studies showed RC cattle clustered with Bos indicus lineage with two distinct haplogroups representing high genetic variability of this breed. These findings can be used for designing proper breeding and conservation strategies for RC cattle in Bangladesh.

Genetic parameters of carcass and meat quality traits in different muscles (longissimus dorsi and semimembranosus) of Hanwoo (Korean cattle)

Bhuiyan, M. S. A.,Kim, H. J.,Lee, D. H.,Lee, S. H.,Cho, S. H.,Yang, B. S.,Kim, S. D.,Lee, S. H. American Society of Animal Science 2017 Journal of Animal Science Vol. No.

<P>We estimated heritability (h(2)) and genetic and phenotypic correlations for carcass and meat quality traits of longissimus dorsi (LD) and semi-membranosus (SM) muscles in 30-mo-old Hanwoo steers. Variance and covariance components were estimated using REML procedures under univariate and bivariate models. The mean carcass weight (CWT), eye muscle area (EMA), back fat thickness (BFT), and marbling score (MS) were 428.20 +/- 46.30 kg, 87.38 +/- 8.54 cm2, 13.00 +/- 5.14 mm, and 5.21 +/- 1.56, respectively. The mean CIE reflectance of meat lightness (L*), redness (a*), and yellowness (b*) were 40.01 +/- 2.73, 22.37 +/- 2.18, and 10.35 +/- 1.46, respectively, in LD muscles and 36.33 +/- 2.44, 22.91 +/- 2.43, and 10.25 +/- 1.65, respectively, in SM muscles. The mean Warner-Bratzler shear force (WBSF), intramuscular fat content (IMF), water-holding capacity (WHC), and protein and ash content in LD and SM muscles were 3.84 +/- 0.96 and 6.52 +/- 1.21 kg, 15.91 +/- 4.39 and 5.10 +/- 1.94%, 62.07 +/- 3.38 and 71.61 +/- 2.06%, 20.01 +/- 1.39 and 21.34 +/- 0.89%, and 0.80 +/- 0.10 and 0.93 +/- 0.07, respectively. The h(2) estimates of CWT, EMA, BFT, and MS were 0.51 +/- 0.13, 0.45 +/- 0.13, 0.29 +/- 0.09, and 0.22 +/- 0.08, respectively. The h(2) estimates were moderate for meat quality traits and were 0.37 +/- 0.12, 0.40 +/- 0.12, 0.33 +/- 0.10, 0.33 +/- 0.10, 0.30 +/- 0.11, and 0.24 +/- 0.09 for L*, WBSF, IMF, WHC, and protein and ash content, respectively, in LD muscle; estimates from SM muscle were comparatively low (0.08 +/- 0.06 to 0.25 +/- 0.09). Estimates of h(2) for a* and b* were also low (0.08 +/- 0.06 to 0.13 +/- 0.07). Carcass weight had a moderate, positive genetic correlation with EMA (0.60 +/- 0.13) and a weak correlation with MS and BFT. The genetic correlations among the 3 colorimeter variants were strong and positive within and between muscles. Intramuscular fat content had moderate to strong and negative genetic correlations with WBSF (-0.49 +/- 0.18), WHC (-0.99 +/- 0.01), and protein (-0.93 +/- 0.04) and ash content (-0.98 +/- 0.06) in LD muscle, whereas the associations were less pronounced in SM muscle. In general, CWT and EMA had low genetic and phenotypic correlations with meat quality traits, which suggests that the traits are independent and have distinct genetic contributions in each muscle. Conversely, with few exceptions, meat quality traits had genetic and phenotypic correlations with MS and BFT. In conclusion, the estimated genetic parameters for carcass and meat quality traits could be used for genetic evaluation and breeding programs in Korean Hanwoo cattle populations.</P>

Design of an Active Inductor-Based T/R Switch in 0.13 μm CMOS Technology for 2.4 GHz RF Transceivers

Bhuiyan, Mohammad Arif Sobhan,Reaz, Mamun Bin Ibne,Badal, Md. Torikul Islam,Mukit, Md. Abdul,Kamal, Noorfazila The Korean Institute of Electrical and Electronic 2016 Transactions on Electrical and Electronic Material Vol.17 No.5

A high-performance transmit/receive (T/R) switch is essential for every radio-frequency (RF) device. This paper proposes a T/R switch that is designed in the CEDEC 0.13 μm complementary metal-oxide-semiconductor (CMOS) technology for 2.4 GHz ISM-band RF applications. The switch exhibits a 1 dB insertion loss, a 28.6 dB isolation, and a 35.8 dBm power-handling capacity in the transmit mode; meanwhile, for the 1.8 V/0 V control voltages, a 1.1 dB insertion loss and a 19.4 dB isolation were exhibited with an extremely-low power dissipation of 377.14 μW in the receive mode. Besides, the variations of the insertion loss and the isolation of the switch for a temperature change from - 25℃ to 125℃ are 0.019 dB and 0.095 dB, respectively. To obtain a lucrative performance, an active inductor-based resonant circuit, body floating, a transistor W/L optimization, and an isolated CMOS structure were adopted for the switch design. Further, due to the avoidance of bulky inductors and capacitors, a very small chip size of 0.0207 mm² that is the lowest-ever reported chip area for this frequency band was achieved.

Estimates of genetic parameters for fatty acid compositions in the <i>longissimus dorsi</i> muscle of Hanwoo cattle

Bhuiyan, M. S. A.,Lee, D. H.,Kim, H. J.,Lee, S. H.,Cho, S. H.,Yang, B. S.,Kim, S. D.,Lee, S. H. Cambridge University Press 2018 Animal Vol.12 No.4

<P>We estimated the heritabilities (<I>h</I><SUP>2</SUP>) and genetic and phenotypic correlations among individual and groups of fatty acids, as well as their correlations with six important carcass and meat-quality traits in Korean Hanwoo cattle. Meat samples were collected from the <I>longissimus dorsi</I> muscles of 1000 Hanwoo steers that were 30-month-old (progeny of 85 proven Hanwoo bulls) to determine intramuscular fatty acid profiles. Phenotypic data on carcass weight (CWT), eye muscle area (EMA), back fat thickness (BFT), marbling score (MS), Warner-Bratzler shear force (WBSF) and intramuscular fat content (IMF) were also investigated using this half-sib population. Variance and covari.ance components were estimated using restricted maximum likelihood procedures under univariate and pairwise bivariate animal models. Oleic acid (C18:1n-9) was the most abundant fatty acid, accounting for 50.69% of all investigated fatty acids, followed by palmitic (C16:0; 27.33%) and stearic acid (C18:0; 10.96%). The contents of saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) were 41.64%, 56.24% and 2.10%, respectively, and the MUFA/SFA ratio, PUFA/SFA ratio, desaturation index (DI) and elongation index (EI) were 1.36, 0.05, 0.59 and 0.66, respectively. The <I>h</I><SUP>2</SUP> estimates for individual fatty acids ranged from very low to high (0.03±0.14 to 0.63±0.14). The <I>h</I><SUP>2</SUP> estimates for SFAs, MUFAs, PUFAs, DI and EI were 0.53±0.14, 0.49±0.14, 0.23±0.10, 0.51±0.13 and 0.53±0.13, respectively. The genetic and phenotypic correlations among individual fatty acids and fatty acid classes varied widely (−0.99 to 0.99). Notably, C18:1n-9 had favourable (negative) genetic correlations with two detrimental fatty acids, C14:0 (−0.76) and C16:0 (−0.92). Genetic correlations of individual and group fatty acids with CWT, EMA, BFT, MS, WBSF and IMF ranged from low to moderate (both positive and negative) with the exception of low-concentration PUFAs. Low or near-zero phenotypic correlations reflected potential non-genetic contributions. This study provides insights on genetic variability and correlations among intramuscular fatty acids as well as correlations between fatty acids and carcass and meat-quality traits, which could be used in Hanwoo breeding programmes to improve fatty acid compositions in meat.</P>

DNA Polymorphisms in SREBF1 and FASN Genes Affect Fatty Acid Composition in Korean Cattle (Hanwoo)

Bhuiyan, M.S.A.,Yu, S.L.,Jeon, J.T.,Yoon, D.,Cho, Y.M.,Park, E.W.,Kim, N.K.,Kim, K.S.,Lee, J.H. Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.6

Sterol regulatory element binding factor 1 (SREBF1) and fatty acid synthase (FASN) genes play an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. This study used polymorphisms in the intron 5 of bovine SREBF1 and in the thioesterase (TE) domain of FASN genes to evaluate their associations with beef fatty acid composition. A previously identified 84-bp indel (L: insertion/long type and S: deletion/short type) of the SREBF1 gene in Korean cattle had significant associations with the concentration of stearic (C18:0), linoleic (C18:2) and polyunsaturated fatty acids (PUFA). The stearic acid concentration was 6.30% lower in the SS than the LL genotype (p<0.05), but the linoleic and PUFA contents were 11.06% and 12.20% higher in SS compared to LL (p<0.05). Based on the sequence analysis, five single nucleotide polymorphisms (SNPs) g.17924G>A, g.18043C>T, g.18440G>A, g.18529G>A and g.18663C>T in the TE domain of the FASN gene were identified among the different cattle breeds studied. Among these, only g.17924 G>A and g.18663C>T SNPs were segregating in the Hanwoo population. The g.17924G>A SNP is a non-synonymous mutation (thr2264ala) and was significantly associated with the contents of palmitic (C16:0) and oleic acid (C18:1). The oleic acid concentration was 3.18% and 2.79% higher in Hanwoo with the GG genotype than the AA and AG genotypes, respectively (p<0.05), whereas the GG genotype had 3.8% and 4.01% lower palmitic acid than in those cattle with genotype AA and AG, respectively (p<0.05). Tissue expression data showed that SREBFI and FASN genes were expressed in a variety of tissues though they were expressed preferentially in different muscle tissues. In conclusion, the 84-bp indel of SREBF1 and g.17924G>A SNP of the FASN gene can be used as DNA markers to select Hanwoo breeding stock for fatty acid composition.

Major Role of the PI3K/Akt Pathway in Ischemic Tolerance Induced by Sublethal Oxygen-Glucose Deprivation in Cortical Neurons In Vitro

Bhuiyan, Mohammad Iqbal Hossain,Jung, Seo-Yun,Kim, Hyoung-Ja,Lee, Yong-Sup,Jin, Chang-Bae 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.6

Ischemic preconditioning can provide protection to neurons from subsequent lethal ischemia. The molecular mechanisms of neuronal ischemic tolerance, however, are still not well-known. The present study, therefore, examined the role of MAPK and PI3K/Akt pathways in ischemic tolerance induced by preconditioning with sublethal oxygen-glucose deprivation (OGD) in cultured rat cortical neurons. Ischemic tolerance was simulated by preconditioning of the neurons with sublethal 1-h OGD imposed 12 h before lethal 3-h OGD. The time-course studies of relative phosphorylation and expression levels of ERK1/2, JNK and p38 MAPK showed lack of their involvement in ischemic tolerance. However, there were significant increases in Akt phosphorylation levels during the reperfusion period following preconditioned lethal OGD. In addition, Bcl-2 associated death promoter (Bad) and GSK-$3{\beta}$ were also found to be inactivated during that reperfusion period. Finally, treatment with an inhibitor of PI3K, wortmannin, applied from 15 min before and during lethal OGD abolished not only the preconditioning-induced neuroprotection but also the Akt activation. Concomitant with blockade of the Akt activation, PI3K inhibition also resulted in activation of Bad and GSK-$3{\beta}$. The results suggest that ischemic tolerance induced by sublethal OGD preconditioning is primarily mediated through activation of the PI3K/Akt pathway, but not the MAPK pathway, in rat cortical neurons.

Developmental Role of Chamber of Commerce and Industries in Bangladesh: A Case Study of Sylhet Chamber of Commerce and Industries

Bhuiyan, Bashir Ahmed,Latif, Abdul KNU The Institute of Management Economy Research 2011 Asia-Pacific Journal of Business Vol.2 No.1

Chamber of commerce and industry plays important role for development of business community and creating vibrant competition. Present paper compares chambers operations in Bangladesh, especially, Sylhet Chamber of Commerce and Industry(SCCI) by reviewing global models of chambers practices. The study identifies important gaps between international standards and Bangladesh practices. Mostly practiced chambers model in the world are: Continental Model, Anglo-Saxon Model and Mixed model or Asian model. Like other Asian countries, chambers in Bangladesh including SCCI, have been following Mixed Model. The empirical study found that SCCI is performing different developmental functions like accumulating members, collecting revenue, fulfilling corporate social responsibility and providing business development services to its members and business community. The notable constraining factors of SCCI operations are: short term orientation in assembling members, limited functional activities, lack of creative endeavors in diversifying services, linkage between SCCI and academic institutions, poor research involvement etc. The necessary suggestions for improvement of chambers performance include adoption of creative measures in various operations, providing training to the members, assisting entrepreneurs in obtaining industrial finance and extending support in the establishment of specialized industrial zone for attaining long term developmental objectives.

Genome-wide association study and prediction of genomic breeding values for fatty-acid composition in Korean Hanwoo cattle using a high-density single-nucleotide polymorphism array1

Bhuiyan, Mohammad S A,Kim, Yeong Kuk,Kim, Hyun Joo,Lee, Doo Ho,Lee, Soo Hyun,Yoon, Ho Baek,Lee, Seung Hwan Oxford University Press 2018 Journal of animal science Vol.96 No.10

Overexpression of AtATM3 in Brassica juncea confers enhanced heavy metal tolerance and accumulation

Bhuiyan, Mohammed Shafi Ullah,Min, Sung Ran,Jeong, Won Joong,Sultana, Sayeda,Choi, Kwan Sam,Lee, Youngsook,Liu, Jang R. Springer-Verlag 2011 Plant cell, tissue and organ culture Vol.107 No.1