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만성 휴지기 탈모증 여성환자의 혈중 저장 철에 관한 연구
이성주 ( Sung Joo Lee ),김영근 ( Young Keun Kim ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.4
N/A Background : Chronic telogen effluvium is a common problem in middle-aged women. It has been suggested that reduced iron stores are a cause of this type of baldness. Objective : We performed this study i order to elucidate the pathogenesis of chronic telogen effluvium and to evaluate the differences in serum stated iron levels between normal females and those with chronic telogen effluvium. Methods : Blood levels of hemoglobin, iron, fortune. and TIBC were examined in 20 patients with chronic telogen effluvican and 20 normal females. Result : 1) Fern tin levels were significantly decreased in the patients group(p=0.008) 2) TIBC levels were significantly increased in the patients group(p=0.001) 3) There were no significant differences in Hb and serum iron in both groups(p>0.05) Conclusion : These findings suggested that the variation f serum ferritin level may play a role in the pathogenesis of chronic telogen effluvium, but further studies will be needed for evaluation of this condition.
성인발병 Still병의 피부 소견에 대한 임상 및 조직학적 고찰
한성협 ( Sung Hyub Han ),최광성 ( Gwang Seong Choi ),신정현 ( Jeonghyun Shin ) 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.4
Background: Adult-onset Still`s disease (AOSD), one of the causes of fever of unknown origin, is accompanied by skin rash. This is the reason why the clinical significance of skin lesions has been of interest. However, its skin manifestations and the histopathological findings are not clearly documented. Objective: This study aimed to identify characteristic clinical and histopathological features of skin manifestation of AOSD. Methods: We evaluated the medical records and histopathologic slides of five patients who had been diagnosed with AOSD in the rheumatology department and referred to our department between 1996 and 2009. Results: An asymptomatic evanescent salmon colored macular rash was seen in three patients (60%). A persistent brown plaque was seen in two patients (40%). Histopathologically, superficial perivascular infiltrates of neutrophils and lymphocytes were observed in all patients (100%) and necrotic keratinocytes were observed in the upper epidermis in three patients (60%). Conclusion: In addition to typical Still`s rash, atypical cutaneous findings such as persistent plaque lesions were found in AOSD patients. The results of this study may help clinicians to diagnose this rare disease more easily. (Korean J Dermatol 2010;48(4):283~289)
Short Report : Acromegaloid Facial Appearance Syndrome with Generalized Hypertrichosis Terminalis
방찬일 ( Chan Yl Bang ),한성협 ( Sung Hyub Han ),변지원 ( Ji Won Byun ),양보희 ( Bo Hee Yang ),송희진 ( Hee Jin Song ),인승균 ( Seung Gyun In ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2011 大韓皮膚科學會誌 Vol.49 No.2
Acromegaloid facial appearance (AFA) syndrome is a rare autosomal dominant disease, consisting of an acromegaloid face, a bulbous nose, and narrowing of the palpaebral fissure. In 1996, Irvin first reported a case of a combination of acromegaloid facial appearance syndrome and congenital hypertrichosis, and reported this case as a new disease of acromegaloid facial appearance with generalized hypertrichosis terminalis, which is differentiated from both AFA syndrome and congenital hypertrichosis/gingival hyperplasia. We report herein the first Korean case of acromegaloid facial appearance with generalized hypertrichosis terminalis. (Korean J Dermatol 2011; 49(2):184~187)
Sodium Tetradecyl Sulfate 경화요법으로 치료한 점액수지낭종 3예
송희진 ( Hee Jin Song ),한성협 ( Sung Hyup Han ),변지원 ( Ji Won Byun ),홍원규 ( Won Kyu Hong ),이현숙 ( Hyeon Sook Lee ),신정현 ( Jeong Hyun Shin ),최광성 ( Gwang Seong Choi ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.9
A digital mucous cyst is a benign, non-inflammatory disease frequently observed on the dorsal aspect of the fingers and toes. Multiple punctures with extraction of the cyst contents and intralesional steroid injections are the suggested treatments. However, this approach has shown a high failure and recurrence rate. Cryotherapy has had a better success rate but it is a more painful procedure. Surgical excision of the communicating tract between the cyst and joint has been reported to have the highest cure rate but it requires highly skilled surgery, and the surgery has the risk of severe complications including contractures of the joints and acquired nail deformity. We report three patients with digital mucous cysts treated by sclerotherapy without complications. (Korean J Dermatol 2008;46(9):1249~1252)