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차혜란,최춘웅 대한건축학회 2023 대한건축학회논문집 Vol.39 No.11
한국 현대 건축사에 있어 2000년대 이후 등장한 ‘젊은 건축가’는 주로 ‘젊은건축가상’ 수상자를 의미하며 이들은 이전 건축가 세대와 구분되는 특징을 가진다. ‘젊은 건축가’들은 한국 현대건축의 새로운 세대로 받아들여지기도 하며 이들과 ‘젊음(youth)’에 대한 담론은 점점 확대되고 있다. 본 연구에서는 '젊은 건축가'들에게서 나타나는 '젊음'을 고찰하고, 주택시장 변동에 대응하여 이들의 변화된 작업 양상을 논한다. 젊은 건축가들이 특히 단독주택, 다가구, 다세대 주택을 비롯한 근린생활시설 등의 작은 규모의 일상적 프로젝트를 접할 기회가 많았다는 사실에 주목하고, 이러한 일상성의 전복으로서 '낯설게 하기' 기법을 사용하며 자신들의 작업을 기존의 건축과 차별화하고 있다는 점을 확인한다. 또한 러시아 형식주의의 문학적 사례로 부터 '낯설게 하기'의 기법을 도출하여 젊은 건축가들의 작업을 분석한다. Within the realm of Korean modern architecture, young architects emerging post-2000 primarily denote those who have earned the KoreanYoung Architect Award. They exhibit distinctive traits setting them apart from the previous generation of architects. These young architectsare gaining recognition as a new wave in contemporary Korean architecture, sparking expanded discussions about youth in this context. Thisstudy delves into the youth of these young architects and explores the changes in their work, influenced by shifts in the housing market. Itemphasizes that young architects now engage in various everyday projects, often small in scale, such as single-family houses, multi-familyhouses, and community living facilities. To set their work apart from traditional architecture, they employ a defamiliarization technique,aiming to disrupt the ordinary. Drawing inspiration from Russian formalism in literature, this study derives defamiliarization techniques andapplies them to analyze the works of young architects.
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심두희,김민정,차혜란,박은선,김아름,박전한,박형천,송대섭,이재면 대한백신학회 2019 Clinical and Experimental Vaccine Research Vol.8 No.1
Purpose: Enzyme-linked immunosorbent assay (ELISA) has been used in the diverse field to evaluate influenza virus infection; for the surveillance, diagnosis, efficacy evaluation, and development of the vaccine. The aim of this study was to establish an ELISA for detecting HA strain-specific antibodies using recombinant pandemic A H1N1 (pH1N1) HA1 (rHA1) protein. Materials and Methods: rHA1 was produced in baculovirus system. The clinical performance of the developed ELISA was validated using human serum samples, by comparison with standard methods for detecting a neutralizing antibody; hemagglutination inhibition (HI) assay and microneutralization test (MNT). The ability of the ELISA system to evaluate the efficacy test of an influenza vaccine was explored by measuring antibody levels in the serum of vaccinated mice. Results: Our ELISA could detect anti-rHA1 antibody in influenza-infected patients and vaccinated subjects. Compared to HI assay and MNT as reference methods, our method showed good performance in detection of anti-rHA1 antibody. Detection of the anti-rHA1 antibody in vaccinated mice and its correlation with titers in HI assay was also proved in a mice model. Conclusion: An ELISA system using rHA1 of pH1N1 influenza virus was developed, and showed good clinical performance in diagnosis of influenza virus infection and evaluation of the vaccination efficacy in both human and animal models.
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