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趙庸均,崔勳,金福麟,李鴻均 인제대학교 1993 仁濟醫學 Vol.14 No.2
조기진통으로 인한 조산은 신생아 사망율 및 유병율의 가장 큰 원인일 뿐만 아니라 이로 인한 경제적 손실도 막대하므로, 조기진통의 원인은 필히 밝혀져야 할 과제인 것으로써, 양막내감염이 조기진통의 원인이 될 수 있는지를 알아보기 위하여 본 연구를 시행하게 되었다. Prematurity is the leading cause of perinatal mortality and morbidity worldwide. Recently many investigators have noted the presence of asymptomatic infection particularly associated with preterm labor. Amniotic fluid was obtained by transabdominal amniocentesis from 50 pregnant women with preterm labor and intact membranes who have been admitted to Sanggye Paik Hospital from Jan. 1, 1992, to Aug. 31, 1992. Their gestational ages ranged from 20 to 36 weeks. The prevalence of a positive amniotic fluid culture was 12% (6/50), and 23.8% (5/21) of patients having delivered preterm neonates had positive amniotic fluid cultures. The isolated organism were Staphylococcus aureus, Bacteroides, E. coli, Candida albicans, and Fusobacterium. Women with positive amniotic fluid cultures had lower gestational ages and more advanced cervical dilatation on admission than women with negative cultures. Preterm infants born to mothers with positive amniotic fluid cultures had a higher incidence of neonatal complications such as respiratory distress syndrome and infection than preterm infants born with negative amniotic fluid cultures. This study reveals that an intraamniotic infection, which is often subclinical in nature, is a major etiologic factor for preterm delivery.
조용균,유태환,서정식,최훈,김복린,이홍균 인제대학교 1995 仁濟醫學 Vol.16 No.3
부인과 영역에 있어서 근래에 급격히 발전하고 있는 골반경 수술에 대한 임상적인 고찰 및 분석(수술적응증, 수술방법, 수술 소요 시간, 수술후 합병증등)을 시행함으로써 향후 골반경 수술의 범위를 더욱 확대시키고 발전시키고자 하였다. The pelviscopic surgery in gynecologic field had been used only for diagnostic procedures and tubal sterilization, but the development of endoscopic equipment, hemostatic method, endocoagulation, video system and laser technology made advanced pelviscopic surgery possible. We have experienced 173 cases of pelviscopic surgery, and came to conclusion that pelviscopic surgery gives less pain, less bleeding and also reduces postoperative pelvic adhesion and hospital-stay -time. With these wonderful advantages, skillful pelviscopic techniques, and development of pelviscopic instruments almost all gynecologic surgery can be performed by pelviscopic procedures in the future.
조용균 대한간학회 2015 간학회 싱글토픽 심포지움 Vol.2015 No.2
Lifestyle interventions including behavioral, dietary, exercise changes can lead to reduction of liver fat and improved glucose control and insulin resistance in non alcoholic fatty liver disease(NAFLD) patients. Until now these approaches are mainstays in the treatment of NAFLD so far. Why should we placing a lot of hope on pharmacologic treatment? Here are couple of reasons why. First, there are lack of evidence in improving Non alcoholic steatohepatitis (NASH) histopathology by lifestyle modification. Second, NAFLD patients have low compliance with physical exercise since adherence to healthy behavior in their lifetime is difficult to achieve. For these reasons, we need to develop newer and effective anti-NASH drug in the near future.
인공무릎관절 전치환술에 있어 축방향 충격에 의한 Tibial Component의 응답 특성 분석 연구
조용균,조철형,최재봉,이태수,최귀원 대한의용생체공학회 1998 의공학회지 Vol.19 No.5
본 연구에서는 동적충격하중 하에서 다양한 tibial component system의 하중전달현상 및 발생 가능한 실패기전을 관찰하기 위해 서로 다른 tibial component들에 대한 수치해석을 통한 응력분포를 관찰하고 또한 접합 상태에 따른 임플란트 시스템이 받는 영향을 비교 분석하였다. 따라서, 해석에 고려되는 모델은 정상 경골과 현재 가장 많이 적용되는 시스템인 시멘트형과 무시멘트형 metal-backed tibial component, 폴리에틸렌으로 된 시멘트형 tibial component, 그리고 골과 slew사이의 비접합상태를 가정한 metal-backed tibial component을 포함한다. 해석 결과 metal-backed tibial component의 stem 끝 부분에서는 시멘트형이 무시멘트형 보다 약간 더 놀은 최대 응력을 보였다. 반면, 폴리에틸렌으로 된 tibial component의 경우 stem 글 부분에서의 최대 응력은 metal-backed tibial component에 비해 차 반 정도로 줄었고, 전체적으로 정상 경골에 유사한 응답 특성을 보여주었다. 골과 stem 사이의 비접합을 가정한 경우 금속 tray 밑 부된에서의 응력은 완전히 접합된 경우 보다 3배 더 높았고, stem 끝부분에서는 시간에 따른 불안정한 응력이 관찰되어 이 현상은 임플란트 해리현상과 불완전한 골접합을 가중시키는 원인으로 사료된다. 따라서, 수직충격하중을 고려한 경우 골에 안정하게 고정되는 폴리에틸렌 tibial component가 가장 바람직하다. In this study, the stress distribution for different tibial components was observed In order to Investigate the load transfer and potential failure mechanism of the tibial components subjected to dynamic impact loading and also to evacuate the effect of bone-implant bonding conditions on the implant system. The 3-dimensional finite element models included an intact tibia, cemented metal-backed tibial component, uncemented metal-blocked tibial component, cemented all-polyethylene tibial component, and metal-backed component with a debonded bone/stem interface. The results showed that the cemented metal-hocked component Induced slightly higher peak stress at stem tip than the uncemented component. The peak stress of the all-polyethylene tibia1 component at stem trip showed about half thats of metal-backed tibial components. The all-polyethylene component showed a similar dynamic response to intact tibia. In case of debonded bone/stem interface, the peak stress below the metal tray was three times Higher than that of the fully bonded interface and unstable stress distribution at the stem tip was observed with time, which causes another adverse bone apposition and implant loosening. Thus, the all-polyethylene tibial component bonded fully to the surrounding bone might be most desirable system under an impact loading.