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정의홍,곽상규,최정윤,이신석,김성규 대한의학회 2019 Journal of Korean medical science Vol.34 No.27
Background: The objective of this study was to identify the effects of mycophenolate mofetil (MMF) on non-renal manifestations in systemic lupus erythematosus (SLE). Methods: The study population comprised 439 SLE patients from the Korean Lupus Network registry who were followed up annually and completed the baseline survey and two follow-up visits from 2014 to 2018. Disease activity, laboratory markers, and clinical manifestations including mucocutaneous lesions, arthritis, serositis, neurological disorders, and hematologic/immunologic abnormalities were assessed. All variables by group (MMF and non-MMF) effects with time (baseline, 1st follow-up, and 2nd follow-up) were analyzed by generalized estimation equation. Results: Seventy-two patients were treated with MMF. There was significant difference in frequencies of malar rash, arthritis, renal disorder, and hematologic disorder between MMF and non-MMF groups in total SLE patients. In subgroup analysis of hematologic abnormalities in total patients, frequency of leukopenia was significantly different between the two groups during follow-up (P = 0.001), but frequencies of hemolytic anemia, lymphopenia, and thrombocytopenia were not. In addition, frequencies of leukopenia in patients without lupus nephritis were significantly decreased in MMF group compared to non-MMF group (P = 0.012). Conclusion: This study showed that MMF might be a beneficial treatment for hematologic abnormalities, especially leukopenia, in SLE.
정의홍 大田大學校 地域社會開發硏究所 1990 地域社會開發硏究 Vol.1 No.-
이 글은 지방화 시대를 맞이하는 지방문단의 현실적 상황을 정치적 종속화의 측면과 발표지면의 확보문제, 그리고 문학인들의 인화관계적 차원에서 오늘날 지방문인들이 당면하고 있는 문제점들을 파헤치고 이를 극복하기 위한 효과적인 방안을 제시하고자 쓰여진다. 어느 시대, 어느 사회든 문화예술과 정치는 밀접한 상관관계를 갖고 있기 마련이다. 사회적 변동에 따라 문예사조가 변혁되어 온 서구사회에서도 문화예술은 정치의 영향권에서 벗어난 적이 그렇게 많지 못함은 주지의 사실이다. 이러한 경우, 항상 제기되던 문제가 바로 문화예술의 정치적 종속화 문제였음은 말할 나위도 없다. 문화예술, 특히 문학이 그 자율적인 독립성을 유지하지 못하고 정치적 상부구조에 종속될 때, 정치도구화란 역기능을 갖거나 심각한 대적 궁핍화 현상을 초래하게 된다.
간세포암에 동반된 난치성 복수를 호전시킨 소양인 환자 치험1례
정의홍,김은희,서영광,최원철,이수경,어완규,Jung, Yee-Hong,Kim, Eun-Hee,Seo, Young-Kwang,Choi, Won-Cheol,Lee, Soo-Kyung,Eo, Wan-Kyu 사상체질의학회 2008 사상체질의학회지 Vol.20 No.2
1. Objectives This is a case of refractory ascites due to hepatocellular carcinoma treated with Sasang Constitutional Medication. Refractory ascites, which did not respond to diuretics, was improved with Jeoryeongchajeonja-tang. 2. Methods We recorded the patient's abdominal circumference, body weight and urine output daily. We also investigated the TTKG(transtubular potassium gradient) values 3 times during the treatment course. 3. Results the TTKG value of the patient was siginificantly decreased. TTKG values before administration of Jeotyeongchajeonja-tang were 8.41, 10.82, respectively and 4.25 after administration of Jeotyeongchajeonja-tang. 4. Conclusions We guess that Jeoryeongchajeonja-tang functions as an aldosterone antagonist or increases spironolactone activity through interaction between Jeotyeongchajeonja-tang and spironolactone. But the mechanism of Jeotyeongchajeonja-tang is not clear, so we need more clinical study of refractory ascites improved with Jeotyeongchajeonja-tang and biological study of interaction between Jeotyeongchajeonja-tang and spironolactone.
鄭義泓 동국대학교 대학원 1983 大學院硏究論集-東國大學校 大學院 Vol.13 No.-
The achievements of research for poems by Youn DongJu can be divided broadly into three types. The first types are the papers in the form of a memorial writing that can hardly be seen as objective criticism. The second are the research papers written in tems of resistance poetry belonging to the category of spiritual history of the dark age under the Japanese rule. The third are the papers analyzing and investigating the poems centering around the Christian spirit of self-sacrifice and the Christian view of the world. The papers in the form of a memorial writing have the effect of telling us of the life of the poet in detail but have their limit as a formal paper. The second types lay too much stress upon ideology and ideas, so that they are deficient in lyricism and poetic taste. The third types are apt to fall into the argumentative fallacy because they pay little attention to analyzing the poems themselves. I think the most desirable way of research is to bring these three phenomenta into harmony instead of being one-sided. In his poetry the poet uses many personal symbols, for instance, stars and the moon that depict his existence and ideals metaphorically and there are many expressions that ask for the identity of me-as durch brochenes Ich-with the world. In this sense I have made researches in his poems from the ontological point of view instead of from resistent or Christian one. As the result, I have come to find the As the result, I have come to find the following aspects in his poems: ⑴ expressions of phanopoeia structure ⑵ what expresses national consciousness with persona through dark ethics ⑶ expressions of affirmative elements of life ⑷ expressions of the spirit of the religious scape goat. I make it clear that this paper describes and analyzes those four aspects by means of the philosophy of Martin Heidegger and Husserl.