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생약복합제제의 약효연구 (제8보) : 작약감초탕이 중추신경에 대한 영향
홍남두(N. D. Hong),김종우(J. W. Kim),정규만(G. M. Jeong),김남재(N. J. Kim) 한국생약학회 1982 생약학회지 Vol.13 No.2
In order to investigate pharmacological actions of combined preparations of crude drugs, Jakyakgancho-Tang were studied. The Jakyakgamcho-Tang using abdominal pain and convulsion of pediatric diseases are composed of Glycyrrhizae Radix and Paeoniae Radix alba. This study was undertaken to investigate the effect of Jakyakgamcho-Tang (S-I) and parched Jakygamchho-Tang (S-II) on anticonvulsive, analgesic, antipyretic and sedative actions. The results of this study were summerized as follows; Both Jakyakgamcho-Tang and parched Jakyakgamcho-Tang showed anticonvulsive effects against convulsions induced by strychnine, picrotoxine and caffeine. Jakyakgamcho-Tang and parched Jakyakgamcho-Tang also showed analgesic and antipyretic effects. Parched Jakyakgamcho-Tang only prolonged the duration of hypnosis induced by sodium pentobarbital.
생약복합제제의 약효연구 (제9보) : 작약감초탕이 장관, 위궤양 부종에 대한 영향
홍남두(N. D. Hong),김종우(J. W. Kim),정규만(G. M. Jeong),김남재(N. J. Kim) 한국생약학회 1982 생약학회지 Vol.13 No.2
This study was undertaken to investigate the effect of Jakyakgamcho-Tang and parched Jakyakgamcho-Tang on anti-inflammatory and antiulcerative actions, and motility of isolated intestine of mice. The results of this study were summerized as follows; Anti-inflammatory effect was showed markedly by the administration of water extract of Jakyakgamcho-Tang and parched Jakyakgamcho-Tang. Isolated intestine of mice was relaxed with the treatment of Jakyakgamcho-Tang and parched Jakyakgamcho-Tang and intestinal contraction induced by BaCl₂ and acetylcholine was also inhibited. The water extract of Jakyakgamcho-Tang and parched Jakyakgamcho-Tang were significantly inhibited Shay`s ulceration in rats.