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이준홍 대한뇌졸중학회 2001 Journal of stroke Vol.3 No.1
Dulplex 초음파 검사는 B-mode 영상검사와 Doppler검사를 같이 하는 검사로서 pulsed wave Doppler는 혈류학적 정보를 그리고 B-mode 영상은 해부학적 정보를 제공함으로써 Doppler sample volume을 혈관내에서 원하는 곳에 위치시키기가 가능하게 하여 주며,또한 angle of insonation의 교정을 가능하게 하여 준다[ 1,2] .이는 현재 신경과 영역에서 많이 시행하는 transcranial Doppler 검사에서의 Doppler만을 사용하였을 때 야기될 수 있는 한계들을 극복할 수 있게 하여 준다.Duplex 초음파검사는 또한 심장박동 동안의 실시간의 혈류학적 변화와 혈관 변화의 평가 등을 가능하게 하여준다.현재 경동맥 duplex ultrasonography는 경동맥,척추동맥,무명동맥(innominate artery)뿐만 아니라 가능한 경우 대동맥궁(aortic arch)까지 검사를 하고 있다.증후성 그리고 무증후성 경동맥 협착증에 있어 경동맥내막절제술의 뇌졸중 예방에 대한 효과는 European(ECST),North American(NASCET)그리고 Asymptomatic Carotid Atherosclerosis studies(ACAS)등 여러 논문에서 보고되어 있어 경동맥 협착증 정도의 측정은 뇌졸중 예방의 측면에서 매우 중요하다.초음파 기술의 발전에 따라 경동맥 duplex 초음파 검사는 더욱 중요한 수술 전 검사가 되고 있으며,현재 혈관촬영 없이 경동맥 초음파검사만으로 경동맥내막절제술을 시행하는 경우가 늘고 있다.경동맥을 침범하는 동맥경화증이 우리나라에서도 증가 추세에 있으므로 앞으로 적용범위가 더욱 넓어질 것으로 생각되며,뇌졸중환자의 검사 및 치료에 있어 경동맥 duplex ultrasonography는 transcranial Doppler와 더불어 중요한 역할을 할 것으로 생각된다. Korean Journal of Stroke 2001;3(1): 40~46
Electrochemical performance of high voltage EDLC with cyclic structure additive added electrolyte
이준홍,박수길,김홍일,육영재 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1
According to necessary for stable high voltage capacitor, we processed experiment for enhancing potential stability. In order to investigate the stable potential area at high voltage, we add cyclic structure additives such as GBL, THF, PC in base electrolyte 1M SBPBF /EC:DMC(1:1), 1M TEABF /EC:DMC(1:1). We measure electrochemical property such as linear sweep voltammetry, ion conductivity, impedance and cyclic voltammetry. So, we will investigate how adaptable these additives at different salt in same electrolyte. Also we try to show how increase the potential stability when we add the each additives. And, we investigate that solvent and charge transfer resistance are decreased for Impedance data.
지주막하 출혈에 따른 Vasospasm에 대한 Transcranial Doppler의 임상적 적용
이준홍,Lee, Jun Hong 대한임상신경생리학회 1999 Annals of Clinical Neurophysiology Vol.1 No.1
Vasoconstriction of intracerebral arteries is the leading cause of delayed cerebral infarction and mortality following aneurysmal subarachnoid hemorrhage. Transcranial Doppler studies show and increase in the flow velocities of basal cerebral arteries, which usually start around day 4 following a subarachnoid hemorrhage, and peaking by days 7 to 14. Angiographic studies confirm the presence of at least some degree of MCA vasospasm when the flow velocities are higher than 100 cm/sec. Mean velocities in the 120 to 200 cm/sec range correspond to 25 to 50% luminal narrowing. MCA and ACA vsospasm is detected with around 90% specificity. Sensitivity is 80% and 50% respectively. A 200cm/sec threshold and rapid flow velocity increase exceeding 50 cm/sec on consecutive days, has been associated with subsequent infarction. Transcranial Doppler is also used to monitor the effects of endovascular treatment of vasospasm. Flow velocities decrease following successful angioplasty or papaverine infusion. Overall, transcranial Doppler studies are considered to have acceptable accuracy for the evaluation of vasospasm in aneurysmal subarachnoid hemorrhage, with limitations that have to be taken into consideration in the clinical setting.
이준홍 대한뇌졸중학회 2000 Journal of stroke Vol.2 No.2
The clinical differentiation between senile dementia of the Alzheimer type and vascular dementia is difficult, and the correlation between clinical and pathological changes is poor. The identification of vascular pathology is important because early management of risk factors may delay onset or reduce the severity of vasculopathy. At present, the diagnosis of cerebral microangiopathy is based on clinical findings, CT and MRI findings. These techniques display the structural consequences of an advanced cerebral microangiopathy. For identification of early stages of small-vessel disease, sophisticated neuroimaging techniques such as positron emission tomography(PET) or single-photon emission computed tomography(SPECT) are required. These methods are expensive, time consuming, and not easily available. Major advantages of neuro-ultrasonographic methods lie in its non-invasive nature and the broad availability of the necessary equipment. Followings are several studies done about neuro-ultrasonographic aids for identification of vascular dementia. Korean Journal of Stroke 2000;2(2): 131~133