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이정열,서용원,이성열,이종석,황규왕 ( Jung Youl Lee,Yong Won Seo,Sung Yul Lee,Jong Suk Lee,Kyu Uang Whang ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.2
Maffuccis syndrome was first reported by Maffucci, in 1881. This syndrome is manifested by multiple enchondromas and hemangiomas, characterized by non-hereditary mesenchymal neoplasia that has a propensity for malignant transformation. Involvement of long bones, particularly the bones of the hands and feet, is most common. The most important complication of this syndrome is the high frequency of chondr osarcomatous metaplasia. We report a case of Maffuccis syndrome in a 56-year-old woman with multiple hemangioma on both the hands and forearms, left foot and enchondromas of multiple bones. The disease started at the age of 8 and was associated with deformity, but malignant transformation was not found. (Kor J Dermatol 1997:35(2): 388-391)
이정열,박영립,황규왕 ( Jung Youl Lee,Young Lip Park,Kyu Uang Whang ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.6
Background: Nerve growth factor(NGF), brain derived neurotrophic factor(BDNF), neurotropin 3(NT-3) and neurotropir-4/5 are neurotrophic factors necessary for the development and maintenance of specific neurors. The tyrosine protein kinase(trk) receptors exhibit specificity for differ ent neurotrophins. NGF is the cognate ligand for the trk A receptor, BDNF binds to trk B receptor and NT-3 binds to irk A, trk B and trk C receptors, Since melanoma cells are devived from neural ectoderm, growth factors which affect. neuronal tissue may have a role in melanoma biology. Objective : The purpose of this study is to demonstrate the presence of trk receptors in rnelanoma cells and observe th effect of K-252a on these melanoma cells growth and differentiation. Methods : After K252a over a range of 0-200nM was added into their cell lines, we exam ined cell viability of SK 28 and SK 30 cells. We performed this to examine the expression of the trk by flow cytometry and immunoblotting. Results : 1. The incubation of . K 28 cells and SK 30 cells with K 252a resulted in a dose dependent inhibition of cell proliferation. 2. In the flowcytometry, SK 28 cells and SK 30 cells showed a high expression of trk A and trk B, not trk C. 3. Using immunoblottiiig, trk in SK 28 cells and SK 30 cells was not expressed. Cpnclusions : These results indicate that. the identification of tyrosine protein kinase reeeptors and their inhibitor which affect differentiation and growth of a melanoma may provide an additional therapeutic option for treatment of melanoma. (Korean J Dermatol 1997;35(6): 1151-1158)
이정열 ( Jung Youl Lee ),이종석 ( Jong Suk Lee ),박준홍 ( Joon Hong Park ),이성열 ( Sung Yul Lee ),황규왕 ( Kyu Uang Whang ),정현 ( Hyun Chung ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.3
Phakomatosis pigmentovascularis is a rare cutaneous malformation characterized by a combination of nevus flammeus and pigmentary nevus such as nevus of Ota, nevus of Ito, mongolian spots, nevus spilus. It is often associated with systemic organ involvement. We report two cases of phakomatosis pigmentovascularis. The first was a 11-year-old boy, who had had diffuse nevus flammeus, mongolian spots since birth, and congenital glaucoma. The second case was a 9-year-old boy who had had nevus flammeus, mongolian spots, nevus of Ota, and nevus of Ito over various parts of his body since birth. He also had leg-length discrepancy, avascular necrosis of the femur head, congenital temporal alopecia and varicose veins. (Korean J Dermatol 1998;36(3): 506-510)
이정열(Lee Jung Youl),윤진희(Yoon JIn Hee),전해성(Jeon Hae Sung),김학범(Kim Hak Beom) 한국정보보호학회 2010 情報保護學會誌 Vol.20 No.1
고속전력선통신(PLC : Power Line Communication)은 전력선을 통신회선으로 이용하여 종래의 방식보다 용이하게 LAN환경을 구축하는 기술이다. 예전부터 전력회사에서 검침 등에 이용되었던 기술이며, 근래에 들어 수십Mbps이상의 고속통신이 가능해지면서 다시금 주목을 받고 있다. 그러나 고속전력선통신은 기존의 네트워크 시스템과는 상이한 몇 가지 특성들을 가지고 있다. 따라서 기존의 보안적인 이슈뿐만 아니라 고속전력선통신 특유의 보안적인 고려도 필요로 하고 있다. 본고에서는 고속전력선통신에 대한 이해를 돕고자 그에 대한 대략적인 개요와 표준화 동향 그리고 고속전력선통신에서 고려해야 할 보안요구사항들에 대해 제시한다.
이정열(Jung-Youl Lee),최홍규(Hong-Kyou Choi),염성배(Sung-Bae Yum),송영주(Young-Joo Song),김종수(Jong-Soo Kim),김태훈(Tae-Hoon Kim) 한국조명·전기설비학회 2010 한국조명·전기설비학회 학술대회논문집 Vol.2010 No.9월
지중에 매설된 금속관(상하수도관, 가스관, 송유관)은 직류 전철에 의해 발생되는 누설전류로 인해 설계 시 예상한 수명보다 짧아지는 경향이 있다. 그 결과 금속관이 누설전류에 의해 전기 부식되어 사고가 발생하는 경우가 발생된다. 본 연구에서 누설전류로부터 지중에 매설된 금속관에 유입되는 누설전류의 영향을 고려하여 초기 방식 설계 설비 시 적절한 수명을 예상할 수 있도록 돕고자 한다. 이를 위해 지중 금속관에 유입되는 누설전류를 양을 구하는 식을 연구하였으며, 각 변수의 대표값을 적용하여 시뮬레이션을 하였다.
박준홍 ( Joon Hong Park ),이정열 ( Jung Youl Lee ),이혜진 ( Hye Jin Lee ),박영립 ( Young Lip Park ),정현 ( Hyun Chung ),황규왕 ( Kyu Uang Whang ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.3
Necrotizing fasciitis is a life-threatening, invasive soft-tissue infection that is characterized by widespread, rapidly developing necrosis of the subcutaneous tissue and fascia with relative sparing of the skin and underlying muscle. In type I necrotizing fasciitis, anaerobes and gram negative bacteria are predominant; in the type II form, Group A p-hemolytic streptococcus is a major etiologic agent. It needs immediate surgical intervention for a favorable outcome. A 64-year-old male presented with extremely painful, erythematous, symmetric, tense swelling with yellowish or hemorrhagic blisters on his right upper extremity. Two weeks before the admission, pain on his elbow made him take acupuncture therapy, There was severe tenderness, pitting edema, and his right elbow showed limited flexibility. The patient underwent wide debridement and drainage immediately. Liquefactive necrosis was seen in the subcutaneous fat and superficial fascia without muscular involvement. Group A B-hemolytic streptococci were grown from the tissue culture specimen. (Korean J Dermatol 1998;36(3) 515-519)
희생양극법과 전류 포집시스템을 이용한 직류철도 누설전류에 관한 연구
유해출(Hai-Chool Yoo),최홍규(Hong-Kyoo Choi),염성배(Sung-Bae Yeum),최대원(Dae-Won Choi),하춘섭(Chun-Sup Ha),이정열(Jung-Youl Lee) 한국조명·전기설비학회 2010 한국조명·전기설비학회 학술대회논문집 Vol.2010 No.9월
최근 환경에 친화적이고 에너지를 유효하게 이용할 수 있으며 안전성과 신속성, 편의성 등 대중 교통수단으로서 여러 가지 이점을 갖고 있는 전기철도는 교통문제 해결의 최선의 대안으로 제시되고 있다. 그러나 직류전기철도에서 발생하는 누설전류에 의해 철도 자체 시설물 및 인근의 지하매설물에 전식이 발생하여 많은 피해가 발생되는 사례가 생겨나고 있다. 따라서 전식에 의한 피해 및 분쟁을 최소화하기 위하여 직류 전기철도에 의하여 발생되는 전식에 대한 대책을 강구하여야 한다. 본 논문에서는 누설전류에 의한 전식 방지 대책 가운데 가장 많이 사용되는 희생양극법을 이용한 전식방지법과 희생양극법의 단점을 보완할 수 있는 누설전류 포집시스템을 이용한 전식방지법을 실험을 통하여 검증해 보았다.
자외선 등의 자극에 의한 인체 멜라닌세포의 타이로신 프로테인 키나제 수용체 발현에 관한 연구
이정열,황규왕,이종석,김영근 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1
Human melanocytes express the p 75 nerve growth factor(NGF) receptors and tyrosine protein kinase receptors(trk) in vitro. Melanocytes are induced to express the p75 NGF receptor in vitro by a variety of phamacologic and physiologic stimuli including UV light. Melanocytes dendricity and migration are regulated in part by NGF. Cultured human epidermal keratino- cytes produce NGF. The purpose of the study was to investigate the influence of UVB and TPA(phorbol 12-tetradecanoate 13-acetate) stimuli in pure melanocytes group and the influence of UVB stimuli in keratinocytes/melanocytes coculture group in the expression of trk A, respectively. Normal human keratinocytes and melanocytes were established from neonatal foreskin. Keratinocytes and melanocytes were cultured by modified Medium 154 and F-10, respectively. Pure melanocytes group and keratinocytes/melanocytes coculture group were respectively exposed to UVB 50 mJ/㎠. pure melanocytes group were treated for 1 day with TPA 50, 100 ng/ml. the expression of trk A in melanocytes with 50 ng/ml TPA was induced about 3 times higher than unstimulated control. But. TPA induction of trk A in melanocytes is not dose-dependent. The expression of trk A in pure melanocytes group and melanocytes/keratinocytes cocultures group with UVB 50 mJ/㎠ was induced about 4-5 times than unstimulated control. We conclude that stimulation with TPA and UVB induces trk A in melanocytes and UVB effect is further potentiated by the presence of keratinocytes in culture.
방성원,이정열,황규왕,정현,김영근 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1
Incontinentia pigmenti achromians(IPA) or Hypomelanosis of Ito is a very rare neurocutaneous syndrome which is often associated with cutaneous, cerebral, musculoskeletal and ocular abnormalities. It is assumed that it is autosomal dominant of inheritance in character. There is also a relationship between IPA and incontinentia pigmenti(IP). However, the etiology of IPA is not known. We describe a 4-year-old girl with myopia, esotropia and retinal pigmentary degeneration in addition to the hypopigmented skin lesion of IPA, and reviewed clinically the cases of IPA in this article.