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      • KCI등재후보

        한약재에 포함된 금속의 다리기전과 후의 농도변화연구 -첩약 / 다린 찌꺼기 / 탕약을 중심으로-

        이선동 대한한의학회 2003 대한한의학회지 Vol.24 No.2

        This study did to get metal concentration change following process steps in Crude, waste after boiling and decoction of herbal drugs in Korea. We measured metal concentration of three steps including Crude, waste after boiling, and decoction from 20 samples patients who visited oriental medical clinic for treat of several diseases through normal action. That result did as like below,first, in the study to acknowledge quality control between in Korea Lab and Harvard Lab in USA from 20 same samples, that result got the same values. So we conformed precision of measurement result in between two Lab. Second, hazardous metal mean concentration in Crude, waste after boiling, and decoction of herbal drugs by follow respectively, it was 32.5㎍/22.1㎍/8.8㎍ in As, 0.0㎍/0.0㎍/0.0㎍ in Cd, 1.0㎍/0.0㎍/0.0㎍ in Hg and 5416.3㎍/3639.6㎍/1002.6㎍ in Pb. These metal concentration decrease 72.9-100.0% compare to crude status. It was also trend the same in the other essential elements. To review these result, we could know intake by decoction method for the purpose the least metal exposure from herbal drugs among the several steps.

      • KCI등재
      • KCI등재

        한의사인력의 수급전망과 대책

        이선동,변진석,김진현,Lee Sun-Dong,Byun Jin-Seok,Kim Jin-Hyun 대한예방한의학회 2004 대한예방한의학회지 Vol.8 No.2

        This paper estimated the demand and supply of physicians for oriental medicine for the period of $2009{\sim}2019$. Two equation models were used in the estimation of manpower. In 2004, the total number of physicians of oriental medicine was amounted to 13,662 registered and 10,532 available in clinical practice, respectively. According to estimates in the study, overall excess supply of physician manpower in oriental medicine was expected in the period, such as $5,300{\sim}5,700$ persons in 2009 and $900{\sim}1,700$ persons in 2019. However, the excess supply would be mitigated after 2019 mainly due to an increase in demand for oriental medical services. Specially, opening medical service market to overseas could be an exogenous variable in physician supply. An alternative manpower policy for oriental medical doctors is needed in a way of controlling oversupply.

      • KCI등재

        생명현상의 다양성과 특징에 관한 고찰 - 보건의료에 미치는 영향을 중심으로 -

        이선동,Lee, Sun-Dong 대한예방한의학회 2010 대한예방한의학회지 Vol.14 No.1

        This research was intended to delve into the diversity of life phenomenon and its characteristics. First of all, this research gave real examples to compare the differences in men's health, disease, and longevity in order to confirm the existence of diversity of life phenomenon. In addition, it also studied the process and mechanism of manifestation of life phenomenon, as well as the influence and problems of existing studies' results and implications. The results are as follow. 1. Differences in health, diseases, and longevity were very big and diverse in researches on different races, nations, ages, socioeconomic status, positions, and even (monozygotic) twins. 2. The basic foundation of all organisms is DNA, and environmental factors change DNA methylation and the structure of chromatin by constantly influencing DNA. Due to this, the manifestation, control, and phenotype of DNA change, resulting in diversified life phenomenon. Therefore, it is the environmental factors, not DNA, that has more influence on the diversity of life. 3. Looking at available studies, the most reasonable perspective on human requires focusing on the diversity of life phenomenon, holistic thinking, and reversible change instead of irreversible determinism. Considerable differences in life phenomenon between entities require a change in malformed perspective on life. Public health and medicine deals with live human beings, a more precise and accurate perspective on life is very important. Because management methods of health and disease, such as structure and approaches of medical research, prevention and cure, must be different by life perspectives.

      • KCI등재

        한국 한의학교육의 발전방안

        이선동,한용주,신규원,Lee Sun-Dong,Han Yong-Joo,Shin Kyu-Won 대한예방한의학회 2004 대한예방한의학회지 Vol.8 No.2

        Problems and current situation of public health globally and domestically were analyzed in this study and based on these findings, ways to improve from western medicine and Oriental medicine can be deduced as follows: 1. Current problems of public health in Korea and the world 1) Increase of diseases resulted from daily habits and infectious diseases, many are at the brink of being ill. Quality of life from extended life span and unbalanced health care must be solved. 2) Natural and societal factors including host factors, public health service, and other external and internal factors play an important role in deciding healthy and being ill. 3) Some of the limits and problems of modem medicine include insufficient academic knowledge and incomplete theory, as well as misled approach to the treatment. Human itself isn't perfect organism and other realistic problems hinder one's well-being. 4) Regardless of western medicine or Oriental medicine, patients were approached as someone with diseases and disorders, and wholistic approach was disregarded. Lack of clinical training, absence of clear educational philosophy and goal are some of the reasons why the education isn't under concrete system 2. Important factors for the medical education and proper direction for the education of Oriental medicine 1) Important factors for medical education - Education should not be limited on the human health and illness, but also cover qualities such as well-being, social welfare, service, and happiness. Every aspects of human life must be considered and attended for more productive outcome. - Basic understanding of humanity must be included in the educational curriculum - Foundation of human diseases and pain are associated with inner life and surrounding causes including family, society, nature, race, culture, religion, politics, and etc., thus the education must be approached to recognize aforementioned criteria. 2) Proper direction for the education of Oriental medicine - Values of Oriental medicine for medical principles and importance of lifehood must be educated. - Educational goal, limits, and levels must be established for the school of Oriental medicine - Respect for life must be the top priorities of educational direction which should lead to solution based education for the human health. Latest medical theory and technology should be accommodated as well as prevention, treatment, and balancing of basic courses and clinical training for optimal education.

      • KCI등재

        가시오가피 에탄올추출물의 AGS위암세포주에서 세포주기억제효과

        이선동,고성규,신헌태,신용철,Lee, Sun-Dong,Ko, Seong-Gyu,Shin, Heon-Tae,Shin, Yong-Cheol 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.3

        Objectives : The research was conducted to confirm the effect of Acanthopanax senticosus harms(ASH) on the anti-tumor activities in AGS human gastric cancer cells. Methods : To examine the potential anti-tumor effect of ASH, we performed many experiments. After processing AGS cancer cells with varying concentrations 80% ethanol ASH extract, analyses by MTT, flow cytometer(FACS) and western blot were used. Results : AGS cancer cells showed decreased cell proliferation and increased contents of S phase when treated with ASH. Moreover, the Western blot experiment showed that ASH affected S phase cell cycle-related molecules(Cyclin A, p21 and p16) in AGS cells. ASH also inhibited EGFR-STAT3 pathway in AGS human gastric cancer cells. Conclusion : Based on these results, we observed that ASH arrested the cell cycle at S phase and inhibited the phosphorylation of EGFR and STAT3 proteins which reduce the cell cycle and the manifestation of the genes that are related to inhibiting cell growth in AGS cells. It can be concluded that ASH can be used in developing medicine for gastric cancer.

      • KCI등재

        한의학적인 생명관의 특징과 건강의 정의

        이선동,박해모,Lee, Sun-Dong,Park, Hae-Mo 대한예방한의학회 2006 대한예방한의학회지 Vol.10 No.1

        With the reduction of contagious diseases throughout the world and prolonged life expectancy has lead into increase of habitual related diseases. Industrial development and better economic situation made people more concerned about their health. As primary illnesses are subdued in the past years, health care system and the public value prevention and well-being more than the treatment itself. Based on this trend, this study focused on the view of life from the perspective of Oriental medicine as it's peculiarities, regimen methods, and the definition of healthy life are evaluated. Following results were obtained: - View of life in Oriental medicine focused on two basic principles of interrelationship between the organs internally, inter-dependency with the natural environment and social surrounding externally as recognition and respect between the medium were valued. - Sustaining and maintaining good health in Oriental medicine are closely related to prenatally healthy pregnancy and fetation, as well as prenatal training. Postnatal maintenance includes accommodation to seasonal changes, adequate food intake, mind control, various regimen methods and avoidance of wrong doings. - Defining health includes body's internal condition and external influences, principles of essence, qi, spirit, and yin and yang, harmony and balance, and individuality. - To conclude, good health in Oriental medicine is defined as 'external adaptation to society and natural environment, and internal balancing of individual difference with accumulation of essence, nurturing and circulating qi, and every material around the body in harmony and balance."

      • KCI등재

        전향적 전후비교환자군과 다중회귀분석방법을 활용한 변증연구 - 117명 건선환자의 양허증과 혈열증를 중심으로 -

        이선동,정세영,권보인,Sundong Lee,Hyundo Kim,Seyoung Jung,Bo-in Kwon 대한한의학회 2023 대한한의학회지 Vol.44 No.2

        Objectives: To study symptom differentiation for yang deficiency and blood heat based on 117 psoriasis patients. Methods: Obtained frequency analysis (%), mean (%), and OR, CL(P-value) with prospective pre-post intervention design and multiple regression analysis. Results: There were no statistically significant differences as to sex, BMI, smoking and marital status, but there were statistically significant differences in variables of average age, family history, and alcohol consumption (P<0.05). There were no statistically significant differences in psoriasis symptoms as to initial age of onset, morbidity span, area of the initial onset, and the progression of psoriasis during the last three months of each patient. However, the type of psoriasis showed a statistically significant difference (p=0.011). While there were no statistically significant differences as to common cold, condition of psoriasis after recovering from the cold, skin condition, exercise, and seasonality, irregular perspiration showed significant difference (p<0.00). When confounding factors have been controlled the blood heat patient group as the comparison group, multiple regression analysis showed OR, CI(95%) of 1.06(0.31-3.63) for men, 0.28(0.08-1.06) for aged 30 to 49,0 and 0.18(0.04-0.80) for aged 50 and older. it was 0.06(0.01-0.7) for family history, 1.06(0.29-3.88) for drink alcohol, 19.90(2.53-156.7) for seasonality, and 10.28 (3.19-33.11) for perspiration problems. In these variables, Sex, age, smoking, and alcohol consumption showed no statistically significant results, but family history(p=0.049), seasonality(p=0.005), and irregular perspiration (p=0.017) were statistically significant. Conclusion: Family history, seasonality and irregular perspiration are the determining factors for yang deficiency and blood heat in psoriasis.

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