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Measuring Structural Distance of 7 TM Proteins Using Joint-based Descriptor
이선구 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1
Joint-based descriptor is a new level of macroscopic descriptor for protein structure using joints of secondary structures as a basic element. Here, we propose how the joint-based descriptor can be applied to examine the conformational distances or differences of transmembrane (TM) proteins. Specifically, we performed three independent studies that measured the global and conformational distances between GPCR A family and its related structures.
이선구 대한건축학회 2004 대한건축학회논문집 Vol.20 No.3
With the entry of the Republic of Korea into the World Trade Organization the architectural education in Korea is experiencing enormous transformation both in it's curricular contents and length of study. The following comparative analysis of the curriculum contents of the three european colleges of architecture - The Bauhaus University of Weimar, Brandenburg University of Technology Cottbus and Technical University Berlin - shows the recent development trend of curricular organization in architectural education in the Federal Republic of Germany and delivers a comparative perspective in shaping 5-year courses of study in korean schools of architecture in the near future.
Identification of Potential Cystatin and Lipocalin Proteins Using OCR-based Fingerprint
이선구 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1
In this study, we employed overlapped conserved residues (OCR) approach to identify sequentially distant homologue of protein scaffolds. The OCR approach generates fingerprints for the family of protein under study by combining conserved residues obtained independently by three alignment methods, i.e. multiple sequence alignment, structure-based alignment and alignment based on the inter-strand hydrogen bonds.