민주주의에서 표의 불평등성: 국회의원 선거구획정의 왜곡도 분석

이상학,이성규 한국의정연구회 2015 의정논총 Vol.10 No.2

본 논문은 현행 국회의원 선거구획정 기준인 선거구 ‘인구수’를 기준으로 선거구획정의 왜곡도를 정치적 지니계수와 획정지수의 분산계수를 이용하여 측정하고자 한다. 측정 결과 인구기준으로 측정한 정치적 지니계수는 유권자기준 정치적 지니계수보다 더 큰 값을 가지는 것으로 나타났다. 또한 인구수를 기준으로 측정한 획정지수의 분산계수도 유권자수를 기준으로 한 분산계수보다 더 큰 값을 갖는 것으로 나타났다. 이러한 결과는 한국의 국회의원 선거구획정이 이상학(2011)과 Lee·Lee(2013)의 측정 결과보다 더 왜곡되어 있음을 나타낸다. 또한 본 논문은 이와 같은 선거구획정의 왜곡이 잠재적으로 인구의 ‘세대별 대표성’에 왜곡을 초래할 가능성에 대해서도 분석하였다. 분석 결과 유아‧청소년층 및 청‧장년층은 전반적으로 과소 대표되고, 노년층은 ‘과다’ 대표되고 있는 것으로 나타났다. 이는 앞으로 지속적으로 늘어날 복지지출 등을 둘러싸고 세대 간 잠재적 갈등이 표출될 가능성을 시사하는 것으로 해석할 수 있다. 마지막으로, 본 논문은 향후 선거구획정의 평가와 관련하여 정치적 지니계수와 획정지수의 분산계수 등과 같은 객관적 기준을 활용할 것을 제안한다. This paper attempts to examine the mal-apportionment in National Assembly election in Korea by extending Lee, Sanghack(2011) and Lee‧Lee(2013). To measure the extent of mal-apportionment, we used both the coefficient of variation of the apportionment index and the political Gini coefficient that are calculated based on population rather than the number of electorate. It turns out that the extent of mal-apportionment based on population is greater than that calculated by the number of voters. In addition, the present paper examines the distortion in representation of age groups resulting from such mal-apportionment. It is shown that the mal-apportionment leads to under- representation of younger generations, but over-representation of old generation. This result implies that there will be potential conflict of interests between age groups in terms of welfare expenditures which are supposed to be increase in Korea. Finally, we suggests that the electoral apportionment be evaluated based on measurable indexes, such as political Gini coefficient and the coefficient of variation of the apportionment index, for more practical debate and consensus.

민주주의에서 표의 불평등성 : 국회의원 선거구획정의 왜곡도 분석

李相學,李城圭 한국의정연구회 2015 의정논총 Vol.10 No.2

본 논문은 현행 국회의원 선거구획정 기준인 선거구 ‘인구수’를 기준으로 선거구획정의 왜곡도를 정치적 지니계수와 획정지수의 분산계수를 이용하여 측정하고자 한다. 측정 결과 인구기준으로 측정한 정치적 지니계수는 유권자기준 정치적 지니계수보다 더 큰 값을 가지는 것으로 나타났다. 또한 인구수를 기준으로 측정한 획정지수의 분산계수도 유권자수를 기준으로 한 분산계수보다 더 큰 값을 갖는 것으로 나타났다. 이러한 결과는 한국의 국회의원 선거구획정이 이상학(2011)과 Lee·Lee(2013)의 측정 결과보다 더 왜곡되어 있음을 나타낸다. 또한 본 논문은 이와 같은 선거구획정의 왜곡이 잠재적으로 인구의 ‘세대별 대표성’에 왜곡을 초래할 가능성에 대해서도 분석하였다. 분석 결과 유아‧청소년층 및 청‧장년층은 전반적으로 과소 대표되고, 노년층은 ‘과다’ 대표되고 있는 것으로 나타났다. 이는 앞으로 지속적으로 늘어날 복지지출 등을 둘러싸고 세대 간 잠재적 갈등이 표출될 가능성을 시사하는 것으로 해석할 수 있다. 마지막으로, 본 논문은 향후 선거구획정의 평가와 관련하여 정치적 지니계수와 획정지수의 분산계수 등과 같은 객관적 기준을 활용할 것을 제안한다. This paper attempts to examine the mal-apportionment in National Assembly election in Korea by extending Lee, Sanghack(2011) and Lee‧Lee(2013). To measure the extent of mal-apportionment, we used both the coefficient of variation of the apportionment index and the political Gini coefficient that are calculated based on population rather than the number of electorate. It turns out that the extent of mal-apportionment based on population is greater than that calculated by the number of voters. In addition, the present paper examines the distortion in representation of age groups resulting from such mal-apportionment. It is shown that the mal-apportionment leads to under- representation of younger generations, but over-representation of old generation. This result implies that there will be potential conflict of interests between age groups in terms of welfare expenditures which are supposed to be increase in Korea. Finally, we suggests that the electoral apportionment be evaluated based on measurable indexes, such as political Gini coefficient and the coefficient of variation of the apportionment index, for more practical debate and consensus.

지정토론 / 이상학

이상학 한국금융연구원 2009 韓國經濟의 分析 Vol.15 No.2

운동강도의 차이가 흰쥐의 심근 세포기질 및 미토콘드리아 LDH 동위효소 변화에 미치는 영향

이상학,윤진환,Lee Sang-Hak,Yoon Jin-Hwan 한국생명과학회 2005 생명과학회지 Vol.15 No.1

생후 7주령 흰쥐를 대상으로 저강도집단, 중강도집단, 고강도집단, 통제집단으로 분리하여 8주 동안 트레드밀 운동을 실시한 후 심장을 적출하여 조직의 세포기질을 분리하고 전기영동을 실시하여 세포기질 LDH 동위효소의 분포양상을 확인하였고, 활성을 측정하였다. 또한 미토콘드리아를 순수분리한 뒤 분리된 미토콘드리아를 외막 내막 막간물질, 매트릭스로 각각 분리하여 각 분획을 전기영동을 실시하고 효소활성을 측정하였다. 운동 강도에 따른 장기간의 지구성훈련으로 심장조직의 세포기질 LDH 동위효소 활성은 운동집단과 비 운동집단에서 모든 LDH 동위효소의 활성을 나타냈다. 세포기질 LDH 동위효소의 운동 강도에 따른 활성변화는 모든 동위효소가 운동강도의 증가에 따라 증가하는 결과를 나타냈으며 모든 강도에서 $AB_3$ 동위효소의 활성이 가장 크게 나타났다. 심장조직 미토콘드리아 각 분획에서 운동 강도에 따른 LDH 등위효소의 분포와 활성은 외막의 경우 다른 분획에 비하여 동위효소의 분포 및 활성이 매우 약하게 나타났다. 운동강도가 증가하면서 모든 분획의 동위효소가 $B_4$쪽으로 활성이 강해지는 현상을 보이며, 외막에서 내막, 매트릭스로 이동하면서 각 분획에 LDH 동위효소의 분포도 많아지고 활성도 또한 증가하는 현상을 나타냈다. To achieve the purpose of this study, forty-eight male Sprague-Dawley rats were assigned to control and three endurance exercise group. 36 rats were forced to exercise according to exercise intensity for 8 weeks and 12 rats were untrained for control group. Cardiac cytosol was extracted from cardiac tissue and cardiac mitochondria was purified from the cytosol. Purified mitochondria were separated into four fraction: inner membrane, outer membrane inter membrane space and matrix. The changes of cytosolic and mitochondrial LDH isozymes activity were measure. Relative activity $(\%)$ of cytosol for low and control group showed the following order of prevalence $AB_3>A_2B_2>B_4>A_3B>A_4$ for moderate and high group : $AB_3>B_4>A_2B_2>A_3B>A_4$. Outer membrane for low group showed $AB_3>B_4>A_2B_2$, for moderate group:$ B_4>AB_3>A_2B_2$, for high and control group: $B_4>A_3B$. Inter membrane space for low, moderate and high group showed $B_4>AB_3>A_2B_2>A_3B>A_4$, for control group: $B_4>A_3B>AB_3>A_2B_2>A_4$. Inner membrane for all group showed $B_4>AB_3>A_2B_2>A_3B>A_4$. Matrix for control, low, moderate and high group showed $B_4>AB_3>A_2B_2>A_3B>A_4$. These results suggest that long term exercise intensity effect on cardiac tissue cytosolic and mitochondrial activity and $A_4,\;A_3B,\;A_2B_2,\;AB_3\;and\;B_4$ isozymes were found entirely in mitochondrial fraction.

Letter to the Editor: Relationship Between Neuropsychiatric Symptoms and Activities of Daily Living in Alzheimer Disease

이상학,Seung-Han Suk 대한노인병학회 2018 Annals of geriatric medicine and research Vol.22 No.1

[Hot News] 170조 원 남북경협 청사진에 접경지 ‘들썩’

이상학 연합뉴스 동북아센터 2018 마이더스 Vol.2018 No.9

Marchiafava Bignami Disease Potentially Complicating Normal Pressure Hydrocephalus

이상학,유인섭,이경회,양현덕 대한치매학회 2014 Dementia and Neurocognitive Disorders Vol.13 No.1

Marchiafava-Bignami disease (MBD) is a rare disorder of demyelination or necrosis of the corpus callosum. Mainly, MBD is associated with alcohol and malnutrition. We report a 60-year-old woman with no history of alcohol consumption or malnutrition who had MBD as a possible complication of normal pressure hydrocephalus (NPH). The patient presented with a 2-month history of progressive gait unsteadiness, urinary incontinence, and forgetfulness, for which the patient underwent ventriculoperitoneal shunt surgery with remarkable improvement. Magnetic resonance imaging (MRI) demonstrated hyperintensity in the body and splenium of corpus callosum when she was brought to the hospital again with rapid deterioration of her mental ststus. It might be postulated that cerebrospinal fluid (CSF) tumor necrosis factor-alpha (TNF-α) might have contributed to the development of MBD although not measured in this patient, given that TNF-α, as a proinflammatory cytokine mediating demyelinating process have been found in be increased in the CSF of NPH.

항고형암제의 활성평가를 위한 in vitro 삼차원 암세포 배양계의 확립

이상학,이주호,구효정 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

For the efficient determination of activity against solid tumors, an in vitro tumor model that resembles the condition of in vivo solid tumors, is required. The purpose of this study was to establish a rapid culture method and viability assay for an in vitro 3-dimensional tumor model, multicellular spheroid (MCS). Among 12 human cancer cell lines, a few cell lines including DUD-1 (human colorectal carcinoma cells) formed fully compact MCS which was adequate for in vitro viability assay. DLD-1 MCS showed steady growth reaching 700 pm diameter after 11 day culture. DUD-1 cells grown as MCS showed significant increase in G_(0)/G₁ phase compared to the monolayer cells (73.9% vs 45.7%). but necrotic regions or apoptotic cells were not observed. The cells cultured as MCS showed resistance to 5-FU (10.3 fold higher IC_(50)) compared to monolayers. however, tirapazamine (a hypotoxin) showed similar activity in both culture systems. In summary, MCS may be a valid in vitro model for activity screening of anticancer agents against human solid tumors and also exploitable for studying molecular markers of drug resistance in human solid tumors.

비가역적인 경과를 보인 메트로니다졸에 의한 뇌병증

이상학,박현영 대한신경과학회 2018 대한신경과학회지 Vol.36 No.2

Optimal number of ports and implications for Korea’s port policy

이상학,조정란 한국무역학회 2017 Journal of Korea trade Vol.21 No.1

Purpose – Many governments around the world have strategically privatized their ports. The privatized ports try to maximize profits by setting higher charges for port services and attracting transship cargos. This paper shows that such privatization of ports can be complemented by adjusting the number of ports. Specifically, the purpose of this paper is to derive the optimal number of ports in cases in which ports serve transship and domestic cargos. Design/methodology/approach – This paper constructs a theoretical model in which ports compete with each other for transship and domestic cargos. In the first stage, the government determines the number of ports. In the second stage, the ports compete with each other in quantity to maximize profits. The authors have derived the optimal number of ports that maximizes national welfare. Findings – The optimal number of ports is expressed as a function of the slope of the demand curve, the slope of the supply curve, and the share of domestic demand relative to total demand for port services. It is shown that the optimal number of ports tends to increase as the share of domestic cargo increases. The optimal number of ports, n*, is given as n*¼1/(1−θ), where θ denotes the share of domestic demand in total demand for port services, when the unit cost of port services is constant. Research limitations/implications – The analysis in the present paper is confined to the case of unilateral intervention by the government of the domestic country. Analyzing interaction among governments via competition policy would offer valuable policy implications. Practical implications – The results of the current research offer important implications for Korean port policy in the context of maritime industrial changes, in particular, China’s New Silk Road initiative. In particular, the findings of this study suggest that Korea’s investment in ports should be concentrated on ports with competitive advantages. Originality/value – Relatively scant attention has been paid to the possibility, or need, of strategic privatization being complemented by governmental competition policy. Filling this knowledge gap, the authors have shown that the government can mitigate the negative effects of privatization on domestic consumer surplus by introducing competition in the supply of port services.