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- 저자 : 이내경 ( Nae Kyung Lee ) (검색결과 2 건)
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연구논문 : 인공 피부, 인공 각막 모델을 활용한 동물실험 대체법 연구의 최근 동향
이내경 ( Nae Kyung Lee ),박현지 ( Hyeon Ji Park ),임경민 ( Kyung Min Lim ) 한국동물실험대체법학회 2014 동물실험대체법학회지 Vol.8 No.1
Cosmetics and drug products must be safe and effective to human and for ensuring their safety and efficacy, animal tests have been widely employed that ensued the sacrifice of numerous experimental animals. However, animal tests impose considerable pains and discomforts to laboratory animals and the results obtained cannot always predict the responses of human accurately. To resolve these ethical issues accompanying animal tests and to obtain more human-relevant test results, reconstructed human tissue models are being actively investigated and employed to animal alternative test methods. Especially, reconstructed human skin and cornea models have advanced into practical application steps in the development of cosmetics. Human reconstructed skin and cornea models provide high degrees of similarity to real human tissues and accordingly, they are expected to be able to produce more human relevant results. Their application to safety and efficacy tests of cosmetics have been continuously expanding. Here we review the current trends in the research of human reconstructed skin and cornea models.
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인공 피부, 인공 각막 모델을 활용한 동물실험 대체법 연구의 최근 동향
이내경 ( Nae Kyung Lee ),박현지 ( Hyeon Ji Park ),임경민 ( Kyung Min Lim ) 한국동물실험대체법학회 2014 동물실험대체법학회지 Vol.8 No.1
Cosmetics and drug products must be safe and effective to human and for ensuring their safety and efficacy, animal tests have been widely employed that ensued the sacrifice of numerous experimental animals. However, animal tests impose considerable pains and discomforts to laboratory animals and the results obtained cannot always predict the responses of human accurately. To resolve these ethical issues accompanying animal tests and to obtain more human-relevant test results, reconstructed human tissue models are being actively investigated and employed to animal alternative test methods. Especially, reconstructed human skin and cornea models have advanced into practical application steps in the development of cosmetics. Human reconstructed skin and cornea models provide high degrees of similarity to real human tissues and accordingly, they are expected to be able to produce more human relevant results. Their application to safety and efficacy tests of cosmetics have been continuously expanding. Here we review the current trends in the research of human reconstructed skin and cornea models.
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