大學生 肺容積 및 最大換氣能에 關한 硏究

尹坪晋,廉哲鎬 中央醫學社 1983 中央醫學 Vol.45 No.6

The aim of this study was to report the lung volume and the maximal voluntary ventilation of the students in the courses of physical and medical education at Chosun university. Subjects were 165 physical students and 74 medical students. The results are as follows: 1) Frequency of breath: (cycle/min, M±SD) Physical male students show 13+3.28, physical female students 17±4.88, medical male students 17+3.51, medical female students 16±4.22. The values of physical male students are represented lower than those of medical male students. There are almost no differences between the two female groups. 2) Vital capacity: (1, M±SD) Physical male students show 4.35±0.610, physical female students 3.45±0.683, medical male students 3.88±0.487, medical female students 2.64±0.318. The values of physical male and female students in common are represented significantly higher than those of medical male and female students. 3) Tidal volume: (ml, M±SD) Physical male students show 684±119, physical female students 677±198, medical male students 482±114, medical female students 468±151. The values of physical male and female students are represented considerably higher than those of medical male and female students. 4) Maximal voluntary ventilation: (1 /min, M±SD) Physical male students show 152.6+12.75, physical female students 117.4±10.24, medical male students 129.7±13.83, medical female students 93.9±11.94. The values of physical male and female students are represented significantly higher than those of medical male and female students.

身體的 律動이 肺 機能에 미치는 影響

廉哲鎬,尹坪晉 조선의대 1984 The Medical Journal of Chosun University Vol.9 No.1

靑少年運動選手의 肺機能에 關한 硏究

尹坪晋,廉哲鎬 朝鮮大學校 附設 醫學硏究所 1983 The Medical Journal of Chosun University Vol.8 No.1

Despite the theoretical problems of the water spirometer and its poor frequency response, the water spirometer is adequate for the physiological function tests even in healthy people. We must encourage the use of the spirometer as part of routine examination of nearly all adult patients. Recently, Pulmonary function studies are widely used in evaluation of various physical condition. The aim of this study was to report the pulmonary function studies of young athletes. Subjects were 221 young athletes from 11 to 17 years of age. They were elementary school boys and girls, middle school boys and girls, high school boys and girls. The following were mainly observed for the study; frequency of breath, vital capacity, tidal volume, and breath holding time. The results obtained were summarized as follow; 1. Frequency of breath; (cycle/min. M±SD) Elementary school boys show 18±5.5, elementary school girls 19±5.0, middle school boys 17±2.3, middle school girls 17±3.0, high school boys 15±6.5, high school girls 15±5.7. 2. Vital capacity; (ℓ, M±SD) Elementary school boys show 1.63±0.138, elementary school girls 1.60±0.241, middle school boys 3.08±0.650, middle school girls 2.79±0.562, high school boys 4.24±0.545, high school girls 2.90±0.792. 3. Tidal volume; (㎖, M±SD) Elementary school boys show 393±40.7, elementary school girls 439±108, middle school boys 590±103, middle school girls 508±78.6, high school boys 727±113, high school girls 618±84. 4. Breath holding time; (sec, M±SD) Elementary school boys show 43±15.5, elementary school girls 45±15.4, middle school boys 53±9.7, middle school girls 46±9.4, high school boys 57±12.9, high school. girls 45±10.1.

신성고혈압쥐에서 Norepinephrine에 의한 혈관수축에 있어 Tyrosine Kinase의 역할

염철호,전제열,윤평진,신무경,조향훈,장정수,홍순표,염충호 대한심장학회 2002 Korean Circulation Journal Vol.32 No.10

吸煙이 肺機能에 미치는 影響(1)

廉哲鎬,尹坪晋 朝鮮大學校 附設 醫學硏究所 1986 The Medical Journal of Chosun University Vol.11 No.1

To examine the effect of cigarette smoking on pulmonary function, we undertook a analysis of 44 smokers and 41 nona dickers whose ages were from 20 to 34 years and who were living' in kwang-ju city. FVC(forced vital capacity), FEV₁ (forced expiratory volume for 1 second), FEF 200~1200, FEF 25~75%, and FEV_(1)/FVC% were calculated by determining the distance from the point of maximum inspiration to the point of maximum expiration. The results obtained were summarized as follows : 1) FVC and FEF 200~1200 showed no significant difference between smoking group and nonsmoking group. 2) In age group 30 to 34 years, FEV₁, FEF 25~75% and FEV₁/FVC% in smoking group were significantly diminished compared with nonsmoking group. 3) It seemed that diminution of forced expiratory volume for 1 second in smoking group is ascribed to diminution of FEF 25~75% of the first expiratory rate. In conclusion, the results of the present study suggested that it may be lead to small airway obstruction by long term cigarette smoking.

吸煙이 肺機能에 미치는 影響(Ⅱ)

廉哲鎬,尹坪晋 朝鮮大學校 附設 醫學硏究所 1988 The Medical Journal of Chosun University Vol.13 No.1

This study was performed to examine the effect of cigarette smoking on pulmonary function, we undertook an analysis of 36 smokers and 33 nonsmokers whose ages were from 35 to 54 years. FVC (forced vital capacity), FEV_(1) (forced expiratory volume for 1 second), FEF_(200∼1200)(forced expiratory flow, 200∼1200 milliliters), FEF_(25∼75)%, and FEV_(1)/FVC% were calculated by determining the distance from the point of maximum inspiration to the point of maximum, expiration with survey spirometer, and expressed in terms of BTPS. The followings were the rusults obtained from this study. 1. Generally, FVC showed no significant difference between smoking group and nonsmoking group, but in age group 50 to 54 years, smoking group was significantly diminishsd compared with nonsmoking group. 2. In aga group 35 to 39 yeard, 45 to 49 years and 53 to 51 years, FEV_(1) and FEV_(1)/FVC% in smoking group were significantly diminished compared with nonsmoking group. 3. FEF_(200∼1200) showed almost no difference between smoking group and nonsmoking group. 4. In age group 35 to 39 years and 50 to 54 years, FEF_(25-75)% in smoking group was significantly diminished compared with nonsmking group.

鬪技種目選手의 肺機能에 關한 硏究

尹坪晉,廉哲鎬 조선의대 1985 The Medical Journal of Chosun University Vol.10 No.1

丹田呼吸運動이 肺機能에 미치는 影響

廉哲鎬,趙東進,尹坪晉,金昌汶,金宋炫,曺徵 조선대학교 1981 The Medical Journal of Chosun University Vol.6 No.-

The expert in pulmonary medicine knows the value of tests of pulmonary function in determining the significance of chronic limitaton of airflow as a possible cause of symtoms and the patient's ability to withstand surgical procedures. We must encourage the use of the spirometer as part of the routine examination of nearly all adult patients. Despite the theoretical problems of the water spirometer and its poor frequency response, the water spirometer is adequate for the physiological function tests even in healthy people. The aim of this study was to report the effect of Danjeun respiration on the pulmonary function tests related to ages. Danjeun respiration which contains various courses is an abdominal respiration. Such a respiration is important for Guksundo. From the many earlier studies in this field, there are many studies on the thoracic respiration. But there appear to be rare studies on the abdominal respiration. Subjects were 152 healthy men from 20 to 55 years of age in the course of Guksundo. The results obtained were as follows. 1) Frequency of breath : (cycles/. min, M±S.D) Represented 14.0±3.5 at the age of 20~24 years, 13.0±2.5 at the age of 20~29 years, 12.0±1.5 at the age of 30~34 years, 12.0±1.9 at the age of 35~39 years, 12.0±4.3 at the age of 40~44 years, 13.0±3.2 at the age of 45~49 years and 12.0±3.6 at the age of 50~55 years. 2) Vital capacity : (㎖, M±S.D) Represented 3,800±354 at the age of 20~24 years, 4, 880±926 at the age of 25±29 years, 4,460±702 at the age of 30~34 years, 3,600±303 at the age of 35~39 years and 2,775±758 at the age of 50~55 years. 3) Tidal volume : (㎖, M±S.D) Represented 476±82 at the age of 20~24 years, 776±186 at the age of 25~29 years, 525±93 at the age of 30~34 years, 494±77 at the age of 35~39, 505±42 at tlie age of 40~44 years, 456±47 at the age of 45~49 years and 426±50 at the of 50~55 years. 4) Breath holding time : (sec, M±S.D) Represented 54±15 at the age of 20~24 years, 73±24 at the age of 25~29 years, 100±40 at the age of 30-34 years, 60±21 at the age of 35~39 years, 51±13 at the age of 40~44 years, 45±9 at the age of 45~49 years and 53±20 at the age of 50~55 years.

Interplay of Hydrogen Sulfide and Nitric Oxide on the Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine

윤평진,Shanker Prasad Parajuli,Dong Chuan Zuo,Pawan Kumar Shahi,오형중,신혜랑,Mi Jung Lee,염철호,최석,전제열 전남대학교 의과학연구소 2011 전남의대학술지 Vol.47 No.2

We studied whether nitric oxide (NO) and hydrogen sulfide (H2S) have an interaction on the pacemaker activities of interstitial cells of Cajal (ICC) from the mouse small intestine. The actions of NO and H2S on pacemaker activities were investigated by using the whole-cell patch-clamp technique and intracellular Ca2+ analysis at 30oC in cultured mouse ICC. Exogenously applied (±)-S-nitroso-N-acetylpenicillamine (SNAP),an NO donor, or sodium hydrogen sulfide (NaHS), a donor of H2S, showed no influence on pacemaker activity (potentials and currents) in ICC at low concentrations (10 μM SNAP and 100 μM NaHS), but SNAP or NaHS completely inhibited pacemaker amplitude and pacemaker frequency with increases in the resting currents in the outward direction at high concentrations (SNAP 100 μM and NaHS 1 mM). Co-treatment with 10 μM SNAP plus 100 μM NaHS also inhibited pacemaker amplitude and pacemaker frequency with increases in the resting currents in the outward direction. ODQ, a guanylate cyclase inhibitor, or glibenclamide, an ATP-sensitive K+ channel inhibitor,blocked the SNAP+NaHS-induced inhibition of pacemaker currents in ICC. Also, we found that SNAP+NaHS inhibited the spontaneous intracellular Ca2+ ([Ca2+]i) oscillations in cultured ICC. In conclusion, this study describes the enhanced inhibitory effects of NO plus H2S on ICC in the mouse small intestine. NO+H2S inhibited the pacemaker activity of ICC by modulating intracellular Ca2+. These results may be evidence of a physiological interaction of NO and H2S in ICC for modulating gastrointestinal motility.

수영선수(水泳選手)의 폐기능검사성적(肺機能檢査成績)

윤평진,염철호,조징,Yoon, Pyung-Jin,Yeum, Cheol-Ho,Cho, Ching 대한생리학회 1982 대한생리학회지 Vol.16 No.1

We must encourage the use of the spirometer as part of routine examination of nearly all adult patients. Despite the theoretical problems of the water spirometer and its Poor frequency response, the water spirometer is adequate for the physiological function tests even in healthy people. The aim of this study was to report the pulmonary function studies of athletic swimmers. Subjects were 85 athletic swimmers from 9 to 25 years of age. They were elementary school boys and girls, middle school boys and girls, high school boys and girls, and college students. The results are as follows: 1) Frequency of breath: (cycle/min, $M{\pm}SD$) Elementary school boys show $19{\pm}4.7$, elementary school girls $22{\pm}7.9$, middle school boys $17{\pm}2.4$, middle school girls $18{\pm}8.2$, high school boys $15{\pm}3.4$, high school girls $15{\pm}9.7$, and college male students $12{\pm}3.2$. 2) Vital capacity: (1, $M{\pm}SD$) Elementary school boys show $2.60{\pm}0.480$, elementary school girls $2.22{\pm}0.412$, middle school boys $3.63{\pm}0.598$, middle school girls $2.80{\pm}0.303$, high school boys $4.70{\pm}0.487$, high school girls $3.23{\pm}0.509$, and college male students $4.30{\pm}0.608$. 3) Tidal volume: (ml, $M{\pm}SD$) Elementary school boys show $462{\pm}59$, elementary school girls $395{\pm}110$, middle school boys $524{\pm}78$, middle school girls $421{\pm}59$, high school boys $612{\pm}101$, high school girls $494{\pm}123$, and college male students $603{\pm}121$. 4) Breath holding time: (sec, $M{\pm}SD$) Elementary school boys show $58{\pm}21.2$, elementary school girls $36{\pm}11.1$, middle school boys $61{\pm}16.7$. middle school girls $53{\pm}21.0$, high school boys $64{\pm}9.1$, high school girls $49{\pm}15.3$, and college male students $81{\pm}23.0$.