Amberlite XAD 수지에 대한 Oxime 화합물의 흡착성에 관한 연구

유의경 세종대학교 1985 세종대학 논문집 Vol.12 No.이공

The adsorption behaviors of some oxime compounds on the Amberlite XAD resins were studied by measuring their distribution coefficients (olg Kd) in various media. The oxime compounds investigated were α-benzoinoxime, dimethylglyoxime, α-furildioxime, nioxime and salicylaldoxime which are well known as chelating agents for some metal ions. The Amberlite XAD resins were XAD-2, XAD-4, XAD-7 and XAD-8. To investigate the experimental factors in measuring log Kd of these oxime compounds, offect of shaking time, concentration of sample, amount of resin, concentration of methanol added and pH in the medium were studied. The decreasing order of log Kd values of the oxime compounds at the given experinental condition was as follows;α-benzoinoxime>salicylaldoxime>α-furildioxime nioxime>dimethylglyoxime (on XAD-2 and XAD-4 resins), while α-benzoinoxime>salicylaldoxime>α-furildioxime>dimethylglyoxime>nioxime (on XAD-7 and XAD-8 resins). The decreasing order of log Kd values of the oxime compounds on the Amberlite XAD resins was as follows: XAD-4>XAD-2>XAD-7>XAD-8

새로운 Azole 항진균제의 합성과 항균활성에 관한 연구

유의경,류성렬,변윤섭 ( Euy Kyung Yu,Seoung Ryuall Ryu,Youn Seop Byoun ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.2

Reaction of cis-and-trans-2-(Bromomethyl)-2-(2,4-dichlophenyl)-1,3-dioxolane-4-methanol(11) with 1-Ethyl-6-fluoro-1,4-dihyddro-4-oxo-7-(1-thiomorpholinyl)quinoline-3-carboxylic acid(8), afforded Azole Ester compounds(12). These Compounds were tested for antifungal and antibacterial activity against Gram-positive and Gram-negative bacteria including Pseudomonas aeruginosa.

어린이를 위한 영양관리

유의경 초록우산 어린이재단 1973 동광 Vol.63 No.-

최초의 미용전문잡지 『위생과 화장』의 미용사적 가치

유의경 근대서지학회 2012 근대서지 Vol.- No.6

폴리우레탄 포움에 대한 히드록시퀴노린의 흡착에 관한 연구

유의경 세종대학교 1981 세종대학 논문집 Vol.8 No.-

The qualitative absorption mechanism of 8-Hydroxyquinoline(8HQ) on polyurethane Foam was studied by their comparative absorption on Amberlite XAD-2 and on Ion-Exchange Resins. The absorption of 8HQ on OPP foam was elucidated by van der Waals forces between 8HQ and OPP foam, and dipole-dipole attraction and hydrogen bonding between hydrxy, carbonyl and amide groups present in OPP foams, The values of Kd was markedly influenced by the following factors: (1) the pH of the media (2) the polarity of sample molecules (3) the ionization constant of sample molecules (4) the salting out effect by adding electrolytes (5) the effect of organic solvents.

Anticancer Agent인 Methotrexate에 대한 새로운 합성 연구

유의경,류성렬,Yu Euy Kyung,Ryu Seoung Ryuall 대한화학회 1993 대한화학회지 Vol.37 No.1

새로운 methotrexate 중간체인 diethyl N-[4-{[(2,4-diamino-6-yl)methyl]-amino}benzoyl]-L-glutamate(10)를 합성하기 위하여 p-nitrobenzoic acid를 chlorination한 다음 L-glutamic acid와 coupling하고 이를 esterification한 후, 환원과 methylation시켜 diethyl N-(4-methylaminobenzoyl)-L-glutamate(7)를 합성하였다. 이 화합물(7)을 DMF 존재하에서 NaH와 allyl chloride를 가하여 allylation한 다음 여기에 $IN_3$ addition 반응으로 diethyl-p-[N-(2-azido-3-iodopropyl)-N-methyl]aminobenzoyl-L-glutamate(9)를 합성하였다. 이 화합물(9)을 2,4,5,6-tetraaminopyrimidine hydrochloride와 cyclization시켜 methotrexate diethylester를 얻었다. New synthetic method for diethyl N-[4-{[(2,4-diamino-6-yl)methyl]-amino}benzoyl]-L-glutamate(10) which is an intermediate of methotrexate is described. p-Nitrobenzoyl-L-glutamate was obtained via a two-step sequence which involves condensation of p-nitrobenzoyl chloride with diethyl-L-glutamate and Fischer esterification reaction with ethanol. Reductive methylation of diethyl-p-nitrobenzoyl-L-glutamate were carried out by reaction with formic acid and paraformaldehyde in the presence of $PtO_2$ catalyst and yielded diethyl N-(4-methylaminobenzoyl)-L-glutamate(7). It was followed by allylation and iodoazidozation to give the diethyl-p-[N-(2-azido-3-iodopropyl)-N-methyl]aminobenzoyl-L-glutamate(9). The cyclization reaction of compound(9) with 2,4,5,6-tetraaminopyrimidine was carried out by intermolecular nucleophilic substitution to give the desired methotrexate diethylester.

Polyacryloylcephalexine과 Polymethacryloylcephalexine의 합성 및 그 항균작용

유의경,권규혁,차월석,나재운,Euy Kyung Yu,Gwon, Gyu Hyeok,Wol Suk Cha,Jae-Woon Na 대한화학회 1993 대한화학회지 Vol.37 No.7

방출조절성 약제를 개발하기 위한 방법으로 polyacrylic acid와 polymethacrylic acid에 thionylchloride로 chlorination하여 cephalexine을 반응시켜 Polyacryloylcephalexine 과 polymethacryloylcephalexine을 합성하였다. Polyacryloylcephalexine 중합체약에 대한 최소 발육 저지 농도로서 항균력은 Micrococcus luteus ATCC 9341과 Escherichia coli ESS이 우수하고, Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, Mycobacterium phlei IFO 3158, Klebsiella pueumouiae KCTC 1560, Escherichia coli KCTC 1039, Salmonella typhimurium KCTC 1925 균주들에 대해서도 항균성이 대체적으로 우수하였다. polymethacryloylcephalexine 중합체약에 대한 최소 발육 저지 농도는 Micrococcus luteus ATCC 9341과 Klebsiella pueumouiae KCTC 1560이 우수하고, Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, Mycobacterium phlei IFO 3158, Escherichia coli KCTC 1039, Escherichia coli ESS, Salmonella typhimurium KCTC 1925 균주들에 대해서는 항균력이 양호하였다. Polyacryloylcephalexine and polymethacryloylcephalexine were prepared by the reaction of polyacryloylchloride or polymethacryloyl chloride with cephalexine. The antimicrobial activities of these polymeric drugs were investigated by the common twofold dilution technique and the minimum inhibitory concentration (MIC) of polymeric durgs was also examined. Polyacryloylcephalexine revealed an excellent antibacterial activity against Micrococcus luteus ATCC 9341, Escherichia coli ESS, Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, Mycobacterium phlei IFO 3158, Klebsiella pueumouiae KCTC 1560, Escherichia coli KCTC 1039, Salmonella typhimurium KCTC 1925. Polymethacryloylcephalexine revealed an excellent antibacterial activity against Micrococcus luteus ATCC 9341, Klebsiella pueumouiae KCTC 1560, Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, Mycobacterium phlei IFO 3158, Escherichia coli KCTC 1039, Escherichia coli ESS, Salmonella typhimurium KCTC 1925.

Pteridine-$C_7$ Side Chain에서 2-탈아미노화와 2-Methyl기 치환에 따른 Aminopterin 중간체 합성에 관한 연구

유의경,류성렬,Yu Euy Kyung,Ryu Seoung Ryuall 대한화학회 1993 대한화학회지 Vol.37 No.1

2-Amino-3-cyano-6-chloromethylpyrazine으로부터 합성한 methotrexate(MTX) 중간 유도체의 모핵인 pteridine ring의 $C_2$-amino 대신 $HCH_3$기, 또는 $nH_2$기로 치환된 화합물 (7a),(7b)와 (7c)를 두 단계에 걸쳐 합성하였다. 출발물질인 dibenzyl 4,4'-dithiobisbenzoate(12)와 2-amino-3-cyano-6-chloromethylpyrazine으로부터 합성한 2-amino-3-cyano-6-[(S-p-carbenzyloxyphenyl)thiomethyl]-pyrazine(14)화합물을 formamidine HCl, acetamidine HCl과 guanidine HCl 등과 각각 반응시켜 cyclization시키고, 이 화합물을 ethanol 용매하에서 0.2N NaOH를 사용한 알칼리 가수분해로 pteroic acid유도체를 합성하였다. A new series of 2-desamino, 2-desamino-2-methyl, and 2-amino analogues of aminopterin intermediates (7a), (7b), and (7c) were synthesized from 2-amino-3-cyano-6-chloromethylpyrazine. These derivatives were synthesized via two step sequence. Thus, cyclization of 2-amino-3-cyano-6-[(S-p-carbenzyloxyphenyl)thiomethyl]-pyrazine(14) with formamidine HCl, acetamidine HCl or guanidine HCl provided condensed compounds (15a), (15b) which upon base hydrolysis yielded the desired products (7a), (7b) and (7c).

2PB-14 / a,b,c-Chlloro Substituted Succinic Acid Drivatives , Its Process and Uses

유의경,오정희,장향동,변윤섭,류성렬 한국공업화학회 2000 한국공업화학회 연구논문 초록집 Vol.2000 No.0

N/A

빅데이터를 활용한 헤어전문점 브랜드별 사회적 인식

유의경,서추연 국제보건미용학회 2023 국제보건미용학회지 Vol.17 No.3

This study attempted to investigate people’s view of beauty salon brands. For this, big data were collected with the words related with JUNO HAIR, RIAHN HAIR and PARK SEUNG CHOL HAIR from the Internet articles and web portals from January 1, 2021 to July 13, 2023. For analysis, TF, IDF and N-gram were performed, using TEXTOM. In addition, network visualization and CONCOR were conducted, using UCINET 6, and the results found the followings: First, in frequency analysis, ‘perm’, ‘color’, ‘dyeing’, ‘haircut’ and ‘clinic’ were observed. In terms of the words with high TF and TF-IDF values, ‘perm’, ‘dyeing’, ‘color’, ‘haircut’, ‘clinic’, ‘designer’ and ‘recommendation’ were found. Second, according to analysis of top 50 words, consumers showed a high interest in ‘treatment’, ‘service policy’, ‘designer’ and ‘region’. Third, in N-gram analysis, ‘treatment’, ‘service policy’ and ‘region’ were discovered. Fourth, according to analysis of correlations among words by visualizing a semantic network, using NetDraw, several words were connected to each other both directly and indirectly without a leaning toward a particular word. Fifth, according to CONCOR analysis, 4 groups were classified by brand. In terms of differences, an academy for intern retraining was found in JUNO HAIR while seasonal promotions were observed in RIAHN HAIR. In contrast, PARK SEUNG CHOL HAIR offered a wig. Consumers tend to choose a beauty salon, considering service policies, services, promotions, location and brand power.