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위장관 ( 胃腸管 ) : 위궤양 환자에서 Omeprazole 반복 투여시 혈청 Gastrin과 Pepsinogen A치의 변화
김만우(Man Woo Kim),박찬국(Chan Gook Park),전용준(Yong Jun Jeon),신양수(Yang Su Shin),유병전(Byung Jeon Yuh),최성도(Sung Do Choi),서영환(Yong Hwan Suh),노상현(Sang Hyun Noh) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.4
N/A The fasting serum gasrin and pepsinogen A levels on oral Omeprazole treatment were observed in 17 patients of gastric ulcer diagnosed by gastrofiberscopy. The fasting serum gastrin and pepsinogen A levels 1 day prior to oral omeprazole treatment, during treatment (1st, 7th, 14th day) and fo]lowing 2 weeks treatment (1st, 7th, 15th day) were monitored respectively and compared each other. The results were as follows. 1) Serum gastrin and pepsinogen A levels during and following the treatment were significantly increased compared to basal gastrin and pepsinogen A levels before treatment each (p<0.01). 2) Serum gastrin levels following the 2 weeks treatment did not change significantly compared to that during treatment. 3) The relationship between the basal serum gastrin levels before treatment and the gasrin levels during the treatment showed positive correlation (r=0.414: p<0.01).