사과주스의 품질에 미치는 pulsed electric field 연속 처리효과

안성환 ( Seong Hwan Ahn ),임정호 ( Jeong Ho Lim ),김영호 ( Young Ho Kim ),정석진 ( Suk Jin Chung ),박기재 ( Kee Jai Park ) 한국식품저장유통학회(구 한국농산물저장유통학회) 2013 한국식품저장유통학회지 Vol.20 No.5

Apple juices were sterilized by continuous pulsed electric field (PEF) treatments of pulse width of 25 μs at electric field intensity of 20.0 kV/cm, and with the varied pulse frequencies of 35 Hz (40 kJ/L), 55 Hz (70 kJ/L), 72 Hz (100 kJ/L) and 85 Hz (130 kJ/L). The PEF treatments of apple juice reduced the microbial counts from 5.3 log CFU/mL of initial state to 3.0 log CFU/mL after PEF treatment at energy density of 130 kJ/L. Also yeast and fungi after PEF treatments were reduced from 5.3 log CFU/mL to 3.0 log CFU/mL and Escherichia coli were from 5.3 log CFU/mL of initial state to 4.7 log CFU/mL to <101 CFU/mL. The soluble solids and free sugars did not significantly differ (p<0.05) depending on conditions of PEF treatment. The total phenolic contents and antioxidant activity such as the DPPH and ferric reducing antioxidant power (FRAP) by PEF treatments were significantly partly reduced, but the PEF-reduced value came in smaller quantities than the heat treatment at 65℃. The iterative PEF treatments with pulse width of 25 μs and pulse frequency of 85 Hz at electric field intensity of 20.0 kV/cm showed limited in microbial reduction. Also, total phenolic contents and antioxidant activity such as DPPH and FRAP, significantly decreased depending on treatment numbers of PEF (p<0.05).

하수처리수 재이용을 위한 카본블럭 여과시스템의 최적운전조건 도출

안성환 ( Seong-hwan An ),조용현 ( Yong-hyun Cho ),김연은 ( Yun-eun Kim ) 한국환경기술학회 2014 한국환경기술학회지 Vol.15 No.5

국내 재이용수는 대부분 하천유지용수에 집중되고 있으며 신도시의 확대에 따라 도시재이용수로의 이용증대가 요구되는 시점에서 하수처리수 재이용수 용도별 수질기준 만족을 위한 최적 3차 처리기술 확보가 필요한 시점이다. 본 연구는 하수처리수 재이용과 처리수 수질개선을 위하여 카본블럭을 이용한 여과 공정을 연계한 시스템 구성을 통해 입자제거 가능성을 평가하는데 목적이 있다. 카본블럭의 수처리 특성을 알아보기 위해 수평형 카본블럭 수처리 모듈로 처리장치를 구성하였다. 실험 결과, 역세공정을 미적용하여 지속적으로 운전할 경우 플럭스는 여과시간에 따라 지속적으로 감소하는 것으로 나타났다. 또한 카본블럭의 여과저항 특성을 살펴보면 플럭스가 감소함에 따라 여과저항은 0.01에서 0.07까지 증가함을 알 수 있다. Domestic reclaimed water is mainly concentrated on river management flow and as new towns are expanding gradually, the usage enlargement toward city reclaimed water is really needed at this stage and securement of the best 3rd process technology is also needed for the satisfaction of water quality standard by use of wastewater as reclaimed water. The aims of this research are focused on wastewater reuse and evaluating the possibility of particle removal through organizing system linked to filtration process using carbon block for the improvement of effluent quality. To examine the characteristics of water treatment of carbon block, we composed processing installation with horizontal carbon block water treatment module. As a result of experiment, in case of constant operation without backwash process it was approved that flux was decreased continuously according to filtration time. And also when focusing on the characteristic of filtration resistance of carbon block, it was approved that the filtration of resistance increased from 0.01 to 0.07 as flux decreased.

크립토스포리디움의 정수처리기준 도입을 위한 문헌 고찰

안성환 ( Seong Hwan An ),조용현 ( Yong Hyun Cho ),김연은 ( Yun Eun Kim ) 한국수처리학회 2013 한국수처리학회지 Vol.21 No.6

In this study, it is studied to find cryptosporidium distribution, target removal rate using risk management method and to set-up Treatment Technique (TT) guideline suitable in domestic treatment plants. It is also researched the case-study in foreign countries for additional removal level of pathogenic protozoan. It is concluded that it is accredited an additional 0.5 Log removal when an effluent turbidity level in a treatment plant meet 0.15 NTU instead of 0.3 NTU and an additional 0.5Log removal when the treatment plant adapt the sand-filtration and GAC process as filtration process. Meanwhile in the case of membrane filtration it is not exceeded the maximum 4 Log removal accreditation calculating by experimental results.

효과적인 정수처리를 위한 크립토스포리디움 목표 제거율 검토

안성환 ( Seong Hwan An ),조용현 ( Yong Hyun Cho ),김연은 ( Yun Eun Kim ) 한국수처리학회 2014 한국수처리학회지 Vol.22 No.1

In terms of public health, it is very important to ensure a safe drinking water from pathogenic microorganisms that cause water-borne disease. Cryptosporidium in the country for the treatment of drinking water treatment regulations standards are being conducted. However, the existing pathogenic protozoa such as cryptosporidium and process operating conditions, etc., for the removal of the need for additional reset. So it is required to install alternative disinfection treatment process for controlling pathogenic protozoan such as cryptosporidium. In this study it was investigated to find cryptosporidium distribution and target removal rate using risk management method. Thoroughout this study it was not reported of any outbreak of waterborne disease case by cryptosporidium. But it is still necessary to investigate a possibility of infection by it. Also it was concluded that target removal rate of cryptosporidium in water treatment plant was required 2 to 4 log at least.

가성뇌종양 증후군으로 발현된 전신성 홍반성 루푸스

안성환 ( Seong Hwan Ahn ),이재진 ( Jae Jin Lee ),김진호 ( Jin Ho Kim ),정원영 ( Won Young Jung ),노준 ( Joon Roh ),김동규 ( Dong Gyu Kim ),고희관 ( Hee Kwan Koh ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.4

Pseudotumor cerebri syndrome is characterized clinically by raised intracranial pressure without ventriculomegaly. Several conditions known to interfere with CSF absorption pathways at the level of the arachnoid villi can produce the pseudotumor cerebri syndrome. Systemic lupus erythematosus (SLE) is an autoimmune, inflammatory and chronic disorder characterized by multi-organ involvement including the nervous system. Clinical evidence of central nervous system involvement includes headache, seizure, psychosis and altered mental status. However, pseudotumor cerebri syndrome has been reported infrequently as a primary feature of central nervous system involvement or a complication of SLE. A 19 year-old female was admitted with seizure preceded by headache and blurred vision. Ophthalmoscopic examination showed papilledema. The diagnosis of pseudotumor cerebri syndrome was confirmed by increased intracranial pres-sure (>550mmH20) in the absence of any abnormal radiological findings of the brain. We described a 19-year old girl whose first clinical manifestation was pseudotumor cerebri syndrome, which was diagnosed as SUE later. Therefore pseudotumor cerebri syndrome may be the part of the spectrum of clinical manifestation of SLE.

난연도료용 인과 염소 함유 변성폴리에스터의 합성 및 분석

안성환 ( Sung Hwan Ahn ),조혜진 ( Hye Jin Jo ),심일우 ( Il Woo Shim ),함현식 ( Hyun Sik Hahm ),박홍수 ( Hong Soo Park ),김승진 ( Seung Jin Kim ),김성길 ( Seong Kil Kim ) 한국유화학회 2006 한국응용과학기술학회지 Vol.23 No.1

무용제형 저기포성 정련제의 제조 및 정련특성

안성환 ( Sung Hwan Ahn ),심일우 ( Il Woo Shim ),조혜진 ( Hye Jin Jo ),함현식 ( Hyun Sik Hahm ),박홍수 ( Hong Soo Park ),김영찬 ( Yeoung Chan Kim ),김성길 ( Seong Kil Kim ) 한국유화학회 2006 한국응용과학기술학회지 Vol.23 No.1

전립선암의 소분할 방사선치료 시에 위치표지자 삽입의 유용성

최영민(Youngmin Choi),안성환(Sung-Hwan Ahn),이형식(Hyung-Sik Lee),허원주(Won-Joo Hur),윤진한(Jin-Han Yoon),김태효(Tae-Hyo Kim),김수동(Soo-Dong Kim),윤성국(Seong-Guk Yun) 대한방사선종양학회 2011 Radiation Oncology Journal Vol.29 No.2

목적: 전립선암의 소분할 방사선치료에서 골반뼈를 기준으로 한 준비자세(setup)와 전립선에 삽입된 위치표지자(fiducial marker)를 이용한 준비자세를 비교하였다. 대상 및 방법: 2009년 9월부터 2010년 8월까지 전립선암으로 근치적 소분할 방사선치료를 받은 4명의 환자를 대상으로 하였다. 방사선치료 1주일 전경에 경직장초음파 검사 하에 3개의 위치표지자를 직장을 통하여 전립선에 삽입하였다. 방사선치료계획용 컴퓨터단층촬영과 매 방사선치료 전에 직장 관장을 하였다. 소분할 방사선치료는 노발리스 장치를 이용하여, 매일 3.5 Gy씩 총 59.5 Gy를 계획하였다. 분할조사 전에 서로 수직인 두 방향의 kV X-선을 촬영하여 얻은 영상의 위치표지자와 방사선치료계획의 디지털재구성사진에서 관찰되는 위치표지자를 융합하여, 환자의 자세를 조정하고 준비자세를 하였다. 위치표지자 기준 준비자세에서 방사선치료계획의 디지털재구성사진과 kV X-선 영상의 골반뼈를 가상적으로 융합하여, 골반뼈 기준 준비자세를 구하였다. 결과: 67회의 분할조사를 분석하였다. 위치표지자 기준 준비자세에서 방사선치료 중심점과의 3차원적 위치 차이의 평균은 0.94±0.62 ㎜ (범위, 0.09~3.01 ㎜; 중앙값, 0.81 ㎜)였고, 좌우, 상하, 전후 방향으로 위치 차이의 평균은 각각 0.39±0.34 ㎜, 0.46±0.34 ㎜, 0.57±0.59 ㎜였다. 골반뼈 기준 준비자세에서 방사선치료 중심점과의 3차원적 위치 차이의 평균은 3.15±2.03 ㎜ (범위, 0.25~8.23; 중앙값, 2.95 ㎜)였고, 상하 방향의 위치 차이(평균, 2.29±1.95 ㎜)가 전후(평균, 1.73±1.31 ㎜), 좌우(평균, 0.45±0.37 ㎜) 방향보다 유의하게 컸다(p<0.05). 위치표지자 기준 준비자세와 골반뼈 기준 준비자세들에서 방사선치료 중심점과의 3차원적 위치 차이가 3㎜ 이상이었던 경우는 전체 분할방사선조사 횟수의 1.5%와 49.3%였고, 5㎜ 이상이었던 경우가 각각 0%, 17.9%였다. 결론: 위치표지자를 이용하여 보다 정확하게 준비자세를 함으로써 계획용표적체적의 여유를 줄일 수 있고, 따라서 전립선 주변의 정상조직에 대한 방사선량을 감소시켜 보다 안전하게 소분할 방사선치료를 할 수 있을 것으로 예상된다. Purpose: To assess the usefulness of implanted fiducial markers in the setup of hypofractionated radiotherapy for prostate cancer patients by comparing a fiducial marker matched setup with a pelvic bone match. Materials and Methods: Four prostate cancer patients treated with definitive hypofractionated radiotherapy between September 2009 and August 2010 were enrolled in this study. Three gold fiducial markers were implanted into the prostate and through the rectum under ultrasound guidance around a week before radiotherapy. Glycerin enemas were given prior to each radiotherapy planning CT and every radiotherapy session. Hypofractionated radiotherapy was planned for a total dose of 59.5 Gy in daily 3.5 Gy with using the Novalis system. Orthogonal kV X-rays were taken before radiotherapy. Treatment positions were adjusted according to the results from the fusion of the fiducial markers on digitally reconstructed radiographs of a radiotherapy plan with those on orthogonal kV X-rays. When the difference in the coordinates from the fiducial marker fusion was less than 1㎜, the patient position was approved for radiotherapy. A virtual bone matching was carried out at the fiducial marker matched position, and then a setup difference between the fiducial marker matching and bone matching was evaluated. Results: Three patients received a planned 17-fractionated radiotherapy and the rest underwent 16 fractionations. The setup error of the fiducial marker matching was 0.94±0.62㎜ (range, 0.09 to 3.01㎜; median, 0.81㎜), and the means of the lateral, craniocaudal, and anteroposterior errors were 0.39±0.34㎜, 0.46±0.34㎜, and 0.57±0.59㎜, respectively. The setup error of the pelvic bony matching was 3.15±2.03㎜ (range, 0.25 to 8.23㎜; median, 2.95㎜), and the error of craniocaudal direction (2.29±1.95㎜) was significantly larger than those of anteroposterior (1.73±1.31㎜) and lateral directions (0.45±0.37㎜), respectively (p<0.05). Incidences of over 3㎜ and 5㎜ in setup difference among the fractionations were 1.5% and 0% in the fiducial marker matching, respectively, and 49.3% and 17.9% in the pelvic bone matching, respectively. Conclusion: The more precise setup of hypofractionated radiotherapy for prostate cancer patients is feasible with the implanted fiducial marker matching compared with the pelvic bony matching. Therefore, a less marginal expansion of planning target volume produces less radiation exposure to adjacent normal tissues, which could ultimately make hypofractionated radiotherapy safer.

고전압 펄스 전기장 처리가 사과의 착즙 특성에 미치는 영향

임정호 ( Jeong Ho Lim ),안성환 ( Seong Hwan Ahn ),이동언 ( Dong Un Lee ),김영호 ( Young Ho Kim ),박기재 ( Kee Jai Park ) 한국식품저장유통학회(구 한국농산물저장유통학회) 2012 한국식품저장유통학회지 Vol.19 No.5

The effects of pretreatment by pulsed electric fields (PEFs) on the juice expression characteristics of the Malus pumila fruit were investigated. Fresh fruits were divided into quarters, were produced on a laboratory scale (100 g apples per lot) by pretreatment with electric fields at two different field intensities (1, 2 kV/cm; n=50, 100, 200, and 400 pulses), and were then pressed at room temperature. Relative to the control samples, the juice yield increased with increasing field intensities. The total phenolics and antioxidant activity were higher in the juice from the PEF-treated fruit than in the juice from the untreated fruit. There was no significant difference in soluble-solid and reducing sugar contents between the PEF-treated and untreated fruits. These results suggest that PEF pretreatment may be useful for increasing the juice yield, total phenolics, and antioxidant activity of the Malus pumila fruit.

활성카본 호안블럭을 이용한 하천수질정화

조용현 ( Yong Hyun Cho ),안성환 ( Seong Hwan An ),김연은 ( Yun Eun Kim ) 한국수처리학회 2013 한국수처리학회지 Vol.21 No.5

In the deposition amount of the biofilm using peanut shaped porous revetment block, formed by microorganisms, to try increasing the self-purification of river. And experiment has compared the ability of the biological self-purification of the activated carbon coated revetment block(ACRB) and existing revetment block(RB). Two reactors of pilot plant were used in this experiment and the comparative study ACRB and existing RB without activated carbon was applied to plant of cycle type-stream. The influent used synthetic water mixing secondary effluent of wastewater treatment plants and stream water. Experiments were operated by separating (Mode1, 2, 3) at low concentrations, middle concentration, high concentration. According to the experiment, biofilm are formed thicker at the Mode 3 substrate concentration of the influent. Result of analysis, the water quality by the removal rate of microorganisms per substrate, is very effective for the removal of BOD, the substrate removal rate of the ACRB is higher than the RB. As a result, ACRB was found that it is possible to improve substrate removal capability friendly environment using microorganisms, to improve the ability of self-purification of river than the RB.