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송한솔,최원복,송준섭,황일태,양승 대한소아내분비학회 2014 Annals of Pediatirc Endocrinology & Metabolism Vol.19 No.4
Purpose: The gonadotropin-releasing hormone agonist (GnRHa) is widely used to treat patients with precocious puberty. However, its effect on growth is often difficult to predict because of the diverse nature of its causes and presentation. This study aims to show the impact of GnRHa treatment on insulin-like growth factor-1 (IGF-I) and IGF binding protein-3 (IGFBP-3) secretion, growth, and on other parameters that may help estimate the height velocity. Methods: Data from 60 girls (mean age, 8.8±0.7 years) treated with GnRHa were analyzed. Their height, bone age (BA), serum IGF-I, and IGFBP-3 concentrations were measured at the start and after a year of GnRHa treatment. To eliminate the confounding effect of chronological age (CA), the standard deviation scores (SDSs) of their height, IGF-I, and IGFBP-3 concentrations according to their CA at the start and after a year of GnRHa treatment were calculated. We looked for possible correlations between these variables and compared the subgroups based on their height velocities and midparental heights. Results: During their one-year GnRHa therapy, height SDS for CA significantly decreased to 0.81±0.83 (P<0.001), but height SDS for BA increased to –0.28±0.68 (P<0.001). There was no significant change in serum IGF-I SDS, IGFBP-3 SDS, and IGF-I/IGFBP-3 ratio. The advanced BA was the factor most strongly correlated to the height velocity (R=0.265, P=0.041). Conclusion: These findings suggest that GnRHa treatment may affect the height velocity due to mechanisms other than suppression of the IGF-I and IGFBP-3 secretory axis.
흡음 석고보드 천장재에 의한 저주파 중량 바닥충격음의 저감 효과
송한솔,류종관,Song, Han-Sol,Ryu, Jong-Kwan 한국음향학회 2018 韓國音響學會誌 Vol.37 No.5
본 연구에서는 흡음 석고보드 천장재에 의한 바닥충격음 저감 효과를 조사하기 위해 잔향실에서의 흡음률 측정과 바닥충격음 성능평가 시험동에서의 바닥충격음 성능평가를 실시하였다. 먼저, 흡음률 측정은 흡음 석고보드, 흡음석고보드+글라스울, 흡음 석고보드 이중 천장재(흡음 석고보드+글라스울+흡음 석고보드)를 대상으로 실시하였다. 측정결과, 흡음 석고보드의 경우 200 Hz과 630 Hz 대역에서 약 0.1~0.5의 흡음률을 나타냈으며, 글라스울을 추가하였을 때 전체 측정 주파수대역(50 Hz ~ 630 Hz)에서 흡음률이 상승하였다. 흡음 석고보드를 추가 설치하였을 때 250 Hz 대역까지 흡음률이 크게 상승하였으나, 315 Hz 이상 대역에서는 흡음률이 감소하였다. 상기 3개의 흡음석고보드 및 일반 석고보드 천장재와 맨슬래브(천장 무) 대상으로 바닥충격음 차단 실험동에서 바닥충격음 차단성능 측정을 실시하였다. 측정결과, 흡음석고보드+글래스울과 흡음석고 보드 이중 천장재의 일반 석고보드 대비 중량충격음의 저감량은 단일평가지수 기준으로 3 dB ~ 4 dB인 것으로 나타났다. 맨슬래브 대비 중량충격음의 저감은 주로 125 Hz ~ 500 Hz 대역에서 발생하였으며 250 Hz 대역에서 최대의 저감량을 나타냈다. This study investigated effects of absorbent gypsum board in the ceiling on low-frequency heavyweight floor impact sound through sound absorption coefficient and floor impact sound measurement. The sound absorption coefficients were measured with sound absorbent gypsum board, glass wool on gypsum board, and a double panel absorbent gypsum board (absorbent gypsum board + glass wool + absorbent gypsum board). Result showed that the absorbent gypsum board had sound absorption coefficient of 0.1 ~ 0.7 from 200 and 630 Hz octave band. The sound absorption coefficient was increased in all frequency range by adding glass wool. Additional absorbent gypsum board increased sound absorption coefficient up to 250 Hz octave band, but decreased over 250 Hz. Heavyweight floor impact sounds were measured in test building for three materials above, gypsum board, and bare slab. Result showed that glass wool on gypsum board and a double panel absorbent gypsum board reduced by 3 dB ~ 4 dB (single number quantity) heavyweight floor impact sound. Comparing with bare slab condition, floor impact sound reduction was mainly found from 125 Hz to 500 Hz octave band, and the maximum reduction was shown in the 250 Hz octave band.