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Hexafluorenium bromide(Mylaxen)사용의 임상경험
오흥근,송수헌,박주열 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1
Hexafluorenium was used to potentiat succinylcholine in 36 patients undergoing major surgery, mainly abdominal, of from ½ to 7 hours duration. Anesthesia consisted of thiopental-nitrous oxide-oxygen-ether or haIothane and ventilation was controlled. In a first group, succinylcholine was administered for intubaticn and repeated intermittently as required with a single dose of hexafluorenium after the intubating dose of succinylcholine had worn off. In a second group, succinylcholine was administered similary but hexafluorenium was also given intermittenly. In a third group, a single initial dose of hexafluorenium was given followed by succinylcholine intermittently. In a fourth group, both drugs were given intermittently throughtout, 1) The apnea time of succinylcholine was prolonged about 8times after a single dose of hexafluorenium in the first and third groups but the prolongation was gradually lessened with successive doses of succinylchohne. Rut in second and fourth groups, the apnea times were significatly prolonged following successive dose of both drugs. 2) In third and fourth groups, fasieulation following succinylcholine was not observed and nausea, vomiting and muscle pains were not noted. 3) In recovery room, about 80% of patients could raise their heads by themselves but ether required longer recovery than halthane. 4) No bronchospasm or cardiovascular side effects were noted. It is considered that this drug combinations provides excellent relatation for surgery. The tech- nique with a single dose of hexafluorenium seems particularlly suitable in cases which last from 30 minutes up to 2 or 3 hours and repeated doses of hexafluorenium and succinylchloin are advisable for longer major cases.
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활성 Alkahne-glutaraldehyde 의 항균작용에 대한 시험관내 실험
고춘명,오흥근,최대경,송수헌,진재신 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1
The discovery of an ideal tecbnique for sterilising contaminated respirators and other anesthesia equipment remains a major problems, The antimicrobial activities of a recently discovered disinfectant alktaline-glutaraldehyde(Cidex), studied in vitro against various speeies of bacteria and fungi. The antimicrobial activity tests were performed according to the modified Kolmer method. The testing organisms were cultured in broth media at 37°C and 25°C for 18 hours to 14 days, and the disinfectant was diluted with sterile distilled;water to 0.4% and 2.0%. One milliliter of cultured broth was transferred into disinfectant-containing media and after 1, 2, 5, 10, 20, 30 and 60 minutes, one loopful of the mateials was removed from the media and inoculated into the broth media. All of the subcultures were incubated at 37°C for 24 hours and fungal subcultures were incubated at 25°C for 14 days. Results were obtained as follows: 1) Most of the bacteria were completely growth-inhibited by treatment with 0.4% activealine-glutaraldehyde solution for 2 minutes except a few strains such as St. aureus, B. subtilis and M. tuberculosis, which required from 16 to 20 min. 2) Mycobacterium tuberculosis was relatively resistant but it could be growth-inhibited by treatment with 2.0% solution for 2 minutes. 3) Growth inhibiting of fungi could be obtained by treatment with 2.0% solation for 5 to 10 minutes.
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Pheochromocytoma 척출술의 마취 : 1례 보고 A Case Report
박광원,오흥근,김박철,송수헌 대한마취과학회 1970 Korean Journal of Anesthesiology Vol.3 No.1
A 54 year-old woman underwent resection of pheochromocytoma under general anesthesia. Following induction of anesthesia with intravenous thiopental sodium, succinylcholine iodide was administered intravenously and endotracheal intubation was performed. Anesthesia was maintained with nitrous oxide, oxygen and diethyl ether using a semi-closed carbon dioxide absorption circle system. The course of anesthesia was rather stormy, reflected by hypertension, arrhythmia and hypotension, but the patient tolerated anesthesia well.
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