http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
고들빼기(Ixeris sonchifolia H.) 성분 및 생물학적 활성에 관한 연구(I)
박수선,Park, Soo-Sun 생화학분자생물학회 1977 한국생화학회지 Vol.10 No.4
식용 및 약용으로 쓰이는 우리나라 야생 식물 고들빼기(Ixeris sonchifolia Hance)의 성분을 분석하여 chlorogenic acid, 7종의 필수 아미노산 및 16종의 총 아미노산을 확인하였다. 아미노산중 proline의 함량이 가장 많았다. 고들빼기의 엑기스는 Ehrlich암에 대해 항암작용을 나타내었다. In Ixeris Sonchifolia H., which is an edible and medicinal plant in Korea chlorgenic acid was identified by P.P.C. and T.L.C. Sixteen total amino acids (Asp, Thr, Ser, Glu, Pro, Gly, Ala, Val, Met, Ile, Leu, Tyr, Phe, Lys, His, Arg) including seven essential amino acids except tryptophan were identified in Ixeris Sonchifolia H. Of these sixteen amino acids, especially proline was contained in the highest amount. The extract of the plant showed an antineoplastic action on Ehrlich carcinoma.
고등 식물중의 Polyphenol 성분에 관한 연구(Ⅳ)
박수선(Soo Sun Park),한정순(Jung Soon Han) 한국생약학회 1975 생약학회지 Vol.6 No.2
Polyphenol substances involved in the browning of Malus asiatica NAKAI (Hong-ok) were examined. It was found that chlorogenic acid was the principal substance. The estimation of polyphenol oxidase activity in Malus asiatica revealed that its browning reaction was caused by enzymatic oxidation of chlorogenic acid.
고등식물 중의 Polyphenol 성분에 관한 연구 (Ⅱ)
박수선(Soo Sun Park) 한국생약학회 1973 생약학회지 Vol.4 No.2
In Peucedanum japonicum and Aster tataricus L. chlorogenic acid was identified by methods of P.P.C. and T.L.C. L-Phenylalanine-U-<sup>14</sup>C and sodium acetate-2-<sup>14</sup>C were administered to Peucedanum japonicum, L-Tyrosine-U-<sup>14</sup>C to Aster tataricus and caffeic acid-carboxyl-<sup>14</sup>C and L-tyrosine-U-<sup>14</sup>C to Fagopyrum esculentum MOENCH. The incorporation of each compound into chlorogenic acid was compared. L-Phenylalanine-U-<sup>14</sup>C showed higher incorporation to chlorogenic acid than sodium acetate-2-<sup>14</sup>C in Pedcedanum japonicum. Caffeic acid-carboxyl-<sup>14</sup>C was higher to chlorogenic acid than L-tyrosine-U-<sup>14</sup>C in Fagopyrum esculentum. L-Tyrosine-U-<sup>14</sup>C was comparatively low in Aster tataricus.
박수선 ( Su Sun Park ),박태영 ( Tai Young Park ) 한국가족관계학회 2015 한국가족관계학회지 Vol.19 No.4
This study, focused on a family therapy case on a male highschool student, examined crisis situation related to suicide, responses from the family, family-related factors that affected crisis situation and the therapist’s intervention method and effectiveness. As a result, conversation held among the family members was not functional and the children were emotionally suppressed due to dysfunctional communication of and continuous conflicts between the parents. The client was compared to his sister by his parents and was treated as a scapegoat in the family. The therapist scrutinized the parents’ family-of-origin and dysfunctional communication method and suggested them a new communication method. Moreover, through probing relationships between parent and child and between two children, the therapist induced insight for improving family interrelationships by helping the parents recognize their children’s situation and strengthened the sibling subsystem. As a result of intervention, the parents became cognizant of their own dysfunctional communication method and relationships with their family-of-origin, and the child’s suicidal behavior gradually reduced after employing distinct boundaries and functional communication method.
고등식물중의 Polyphenol 성분에 관한 연구 (Ⅲ)
박수선(Soo Sun Park),김경순(Kyung Soon Kim) 한국생약학회 1973 생약학회지 Vol.4 No.4
In Cnidium officinale MAKINO and Platycodon grandiflorum A. DE CANDOLE, chlorogenic acid was identified by Rf values, color reactions on paper chromatograms and UV-absorption spectra of the eluate of phenolic spots. And isochlorogeni acid-like substance was also found in the former. l-Phenylalanine-U-C<sup>14</sup> and sodium acetate-2-C<sup>14</sup> werse fed to both plants and their incorporation ratio to chlorogenic acid and isochlorogenic acid-like substance was compared, Phenylalanine was better precursor for chlorogenic acid in both plants than acetate. But acetate showed higher incorporation ratio to isochlorogenic acid-like substance in Cnidium officinale than that of phenylalanine.
아미노산류가 들깨잎 폴리페놀 옥시다제 활성저해에 미치는 영향
박수선(Soo Sun Park),김안근(An Keun Kim),손은수(Eun Soo Sohn) 대한약학회 1996 약학회지 Vol.40 No.1
Characterization of Polyphenol oxidase (PPO) in Perillae Folium, particullarly inhibitor studies were investigated. This enzyme was stable at pH 5.0 and the residual activity of PPO at >or= ph 5.5 was estimated to be very low. PPO activity was decreased slightly by adding amino acid with catechol as a substrate, particullary PPO activity was inhibited markedly by cystein, histidine, lysine and arginine. In the absorption spectra of the product formed when catechol was oxidized by PPO, with a ramdamax at 410nm, the peak shifted toward ramdamax 520nm by addition of L-proline. At relatively low concentrations(10-3M), sulfite and dithiothreithol completely inhibited PPO activity. Inhibition of PPO activity by amino acids and inhibitors increased or decreased depending on the pH used to measure it
한국산 재래종 담배잎에서 정제한 Polyphenol Oxidase의 성상에 관한 연구
박수선(Soo Sun Park),김안근(An Geun Kim),박금영(Geum Young Park) 한국생약학회 1989 생약학회지 Vol.20 No.2
Purification of polyphenol oxidase(PPO) from Korean native tobacco variety leaves was carried out through the procedure of acetone preciptation, ammonium sulfate fractionation, and Sephadex G-150 gel filtration, resulting in a 84-fold increase in specific activity. The enzyme was stable in a range of pH 7.5 to 8.0 with an optimum of pH 7.5, The optimum temperature for the enzymic reaction was about 60°. It was thermostable with a half-life equal to 20 min at 70°. Km values for (+)-catechin and pyrogallol were 1.6×10^(-3) and 0.5×10^(-3) M, respectively. It possesses high catecholase activity but little or no cresolase activity. Lineweaver-Burk analysis of inhibition data revealed that the inhibition of (+)-catechin oxidation by potassium cyanide, 4-nitrocatechol, cystein and 2-mercaptoethanol was competitive with Ki values of 1.1×10<sup>-6</sup>, 1.8×10<sup>-6</sup>, 8.9×10<sup>-6</sup> and 1.3×10^(-5) M, respectively.
박수선(Soo Sun Park),김안근(An Keun Kim) 한국생약학회 1984 생약학회지 Vol.15 No.2
Polyphenol oxidase was purified from acetone powder extract of the root of Ixeris sonchifolia. The enzyme obtained by ammonium sulfate fractionation and sephadex G-200 gelfiltration gave 51-fold purification over the crude extract. The purified enzyme showed activity toward chlorogenic acid, caffeic acid and pyrocatechol. The kinetics of thermal inactivation of the enzyme followed first-order reaction. Potassium cyanide and cysteine were potent inhibitors.