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뇌졸중환자의 고지혈증에 대한 평진건비탕가감방의 임상적 효과
박상은,홍수현,권오순,서창운,민성순,홍상훈,Park, Sang-Eun,Hong, Su-Hyun,Kwon, O-Sun,Seo, Chang-Woon,Min, Sung-Soon,Hong, Sang-Hoon 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3
Objectives : This study was aimed at examining significant curative effects of Pyungjingunbitanggagam-bang on CVA(Cerebral Vascular Accident) patients with hyperlipidemia. Methods : The subjects in this study were sixteen patients admitted to Dong-Eui University Oriental Hospital who broke out with CVA from November 2004 through August 2005, with high total cholesterol (240mg/ dl above) or high TG (200mg/dl above). Before prescription. they were tested for total cholesterol, ALT. AST. BUN. and creatinine with fasting and were then prescribed the herbs(Pyungjingnnbitanggagam-bang) for 2 weeks. after which they were retested for total cholesterol. ALT. AST. BUN. and creatinine every 2 weeks. Conclusions : In the whole treatment group, hypertension & DM group. and cerebral infarction group.statistical significance of total cholesterol changes was recognized before and after the treatment.. Pyungjingunbitanggagam-bang decreased total cholesterol in HT. DM. and cerebral infarction groups. In the whole treatment. HT. and DM groups. statistical significance of TG changes was not recognized before and after the treatment. Hepatotoxicity and nephrotoxicity did not appeared when a stroke patient was given Pyungjingunbitanggagam-bang.
약침요법(藥鍼療法)을 통한 췌장암환자의 천등(천증) 치험(治險) 1례(例)
박상은,서상호,홍수현,김재연,신원탁,윤현민,홍상훈,Park, Sang-Eun,Seo, Sang-Ho,Hong, Su-Hyun,Kim, Jae-Yeon,Shin, Won-Tak,Youn, Hyoun-Min,Hong, Sang-Hoon 대한약침학회 2006 Journal of pharmacopuncture Vol.9 No.1
Objectives : This study planed to evaluate effect of oriental medicine therapy treatment method of dyspnea that happen from cancer of the pancreas patient who accompany Multiple metasis Methods : Patient complained dyspnoea during admission into dept. Of internal medicine, college of oriental medicine, Dong-eui Univ, was appealed patient treated by Oriental medicine therapy that is of use Herb Medication and Herbal -acupuncture Treatment being diagnosed in lung asthenia including deficiency of Eum and insufficiency of Gi of the lung(肺虛), the fire due to deficiency(虛火), and loving warfare of symptoms evaluated through VAS (visual analog scales). Results & Conclusion : Patient's difficulty in breathing symptoms took a favorable turn after treatment. This study means that Oriental medicine therapy that is difficulty in breathing symptoms that happen from patient surely has effectiveness.
뇌졸중환자의 정구성정색소성 빈혈에 대한 사육탕가미방의 임상적 효과
박상은,홍수현,장자원,송수진,홍상훈,서상호,Park, Sang-Eun,Hong, Su-Hyun,Jang, Ja-Won,Song, Su-Jin,Hong, Sang-Hoon,Seo, Sang-Ho 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.4
Objective : Normocytic Normochromic Anemia is one of the most common cases in clinics of all types of morphological Anemia. This study is aimed at examining significant curative effects of Sayuktanggami-bang on Cerebral vascular accident(CVA) patients with Normocytic Normochromic Anemia. Methods : For this study to examine the effects of Sayuktanggami(四六湯加味方), Patients were divided into 2 groups. Group A(experimental group) consisted of 19 cases prescribed Sayuktanggami-bang, Group B (control group) consisted of 15 cases prescribed other herbs. Before presciption, They were tested for CBC, AST, ALT, Total protein, Cholesterol, TG, HDL, BUN, Creatinine, Uric acid, Na, K, Cl while fasting, then were given the herbs over two weeks. They were checked again for changes over those two weeks. Results : In cases of group A, the statistical significance of CBC changes before and after treatment were recognizable : RBC(p<0.01), Hb(p<0.01), Hct(p<0.01). In comparing CBC changes between group A and group B which developed cerebral infarction group, a type of CVA, the significance of curative effects in group A is recognizable over group B before and after treatment : RBC(p<0.01), Hb(p<0.01), Hct(p<0.05). Cytotoxic reaction was nonexistant. Conclusion : Results of this study suggest that Sayuktanggami-bang has curative effects for CVA patients with normocytic normochromic anemia.
하지 관절경 수술에 대하여 시행된 항응고 요법에 의한 혈액 응고 검사의 변화 : Enoxaparin versus Rivaroxaban
박상은,백영웅,김종대,Park, Sang Eun,Back, Young Woong,Kim, Jong Dai 대한관절경학회 2012 대한관절경학회지 Vol.16 No.2
Purpose: To compare coagulation test results of the arthroscopic surgery patients who received thromboprophylaxis with typical two kinds of anticoagulation drugs, we performed coagulation tests before and after surgery with two groups and then compared the results. Materials and Methods: Forty-seven patients who underwent arthroscopic surgery were randomly divided into two groups to rivaroxaban and enoxaparin group, and we performed coagulation tests before and 5 days after arthroscopic surgery to two drugs groups in order to investigate about the difference in clotting capacity. Results: Preoperative coagulation tests did not differ significantly between the two groups. However, coagulation tests after 5 days of the surgery, the level of prothrombin time-international normalized ratio (PT-INR), activated partial thromboplastin time (aPTT) increased, particularly in patients with rivaroxaban compared with enoxaparin (P<0.05). Conclusion: Anticoagulation for arthroscopic surgery with a drug is effective and has safe range in terms of bleeding tendency, but in the rivaroxaban group, there was one patient who showed high bleeding tendency with abnormal range. Therefore it should be careful of using rivaroxaban for thromboprophylaxis. 목적: 관절경 수술을 시행 받은 환자의 항응고 요법이 응고능에 미치는 영향과 대표적 항응고 약물 사이에 차이가 있는지 알아보기 위하여 항응고 약물 중 두 종류를 선택하여 사용한 환자들의 혈액 응고 검사를 수술 전후에 시행하여 수술 전 후 및 두 약물 간에 차이가 나타나는지에 대해 알아보았다. 대상 및 방법: 관절경 수술을 시행한 47예의 슬관절 혹은 고관절 환자를 대상으로 하였으며 환자군을 무작위로 enoxaparin과 rivaroxaban을 사용한 두 그룹으로 나누어 수술 전 및 수술 후 5일째 응고 검사를 시행하여 수술 전후 및 두 약물간의 결과를 비교하였다. 결과: 수술 전 시행한 응고 검사에서는 두 그룹간의 유의한 차이가 없었으나(P>0.05) 수술 후 5일째 시행한 응고 검사에서는 prothrombin time-international normalized ratio (PT-INR), activated partial thromboplastin time (aPTT)에서 증가 소견을 보였고 특히 rivaroxaban 환자군의 수치가 증가한 것으로 나타났다(P<0.05). 결론: 관절경 수술의 약물을 통한 항응고 요법은 혈액 검사를 통한 결과에서 출혈 경향 면에서 안전한 범위에서 수술전과 비교하여 통계적으로 유의한 차이를 보였으나 rivaroxaban을 사용한 환자 군에서 응고능의 정상 범위를 넘어서는 환자가 있어 rivaroxaban의 사용에 주의를 요할 것으로 생각된다.