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민선양 ( Sun Yang Min ),박주이 ( Ju Yee Park ),윤재영 ( Jae Young Yoon ),홍승권 ( Sung Geon Hong ),김도훈 ( Do Hoon Kim ),김현미 ( Hyun Mi Kim ),박해심 ( Hae Sim Park ),최정희 ( Jeong Hee Choi ) 대한천식알레르기학회 2006 천식 및 알레르기 Vol.26 No.1
Perilla is a Korean traditioanal crop and perilla seeds are frequently consumed in many food products as seasonings and seed oil in this country. To our knowledge, this is the first report on perilla seeds-induced anaphylaxis and specific IgE determination to perilla seeds. We experienced a 20-year old man who had developed whole body urticaria, facial swelling, and shortness of breath 2 hours after eating two dumplings seasoned with perilla seeds. He had developed two more episodes of allergic reactions after eating some food seasoned with perilla seeds before. The skin prick test with perilla seed extracts showed strong positive reactions, and serum specific IgE antibodies to perilla seeds were highly detected by ELISA. Oral provocation test showed rhinitis, conjunctivitis, urticaria, and severe asthmatic reaction. (Korean J Asthma Allergy Clin Immunol 2006; 26:94-97)
박주이 ( Ju Yee Park ),윤재영 ( Jae Young Yoon ),민선양 ( Sun Yang Min ),홍승권 ( Seung Kwon Hong ),박주상 ( Ju Sang Park ),장은정 ( Eun Jeong Jang ),백현욱 ( Hyun Wook Baik ),박상종 ( Sang Jong Park ) 대한소화기학회 2007 대한소화기학회지 Vol.50 No.3
Pneumatosis cystoides intestinalis is an uncommon condition of unknown etiology, characterized by the presence of multiple gas filled cysts in the gastrointestinal tract. Many different causes of pneumatosis cystoides intestinalis have been proposed, including mechanical, pulmonary, and bacterial causes. Approximately 85% of cases are thought to be secondary to coexisting disorders of the gastrointestinal tract or the respiratory system. The condition has been associated with the therapeutic uses of lactulose, steroids, and various cancer chemotherapeutic regimens. Lactitol is a disaccharide analogue of lactulose which is available as a pure crystalline powder. There are three previous case reports suggestive of lactulose causing pnumatosis intestinalis. We report a case of recurrent pneumatosis cystoides intestinalis associated with benign recurrent pneumoperitoneum developed probably secondary to lactitol therapy. (Korean J Gastroenterol 2007;50:188-192)
비용 및 만성 비,부비동염 환자에서 잠재된 아스피린 과민성 천식의 유병률
박지원 ( Ji Won Park ),정덕희 ( Duk Hee Chung ),김석화 ( Seok Hwa Kim ),서범석 ( Beom Seok Seo ),민선양 ( Sun Yang Min ),최정희 ( Jeong Hee Choi ) 대한천식알레르기학회 2007 천식 및 알레르기 Vol.27 No.3
Background & Objective: Aspirin-intolerant asthma (AIA) is a distinct clinical syndrome characterized by aspirin sensitivity, asthma, and nasal polyposis (NP). The incidence of AIA in adult asthmatics is 8∼20%, and the prevalence of AIA among adult asthmatics with NP and/or chronic rhinosinusitis further increases to 30∼40%. However, the prevalence of subclinical AIA in patients with NP and/or chronic rhinosinusitis has rarely been investigated. Method: A total of 36 patients with NP and chronic rhinosinusitis who was scheduled for polypectomy were enrolled. All had no previous history of AIA. Lysine-aspirin bronchoprovocation tests were performed on all subjects before operation. Positive response was defined as a >15% fall in FEV1 from baseline. Result: Five of 36 patients (13.8%) showed positive responses to lysine-aspirin provocation tests (4 subject with NP+asthma and 1 with NP alone, P<0.05). There was a significant difference in the PC20 to methacholine between AIA+NP and NP+asthma groups (0.22±0.37 vs. 3.13±2.70 mg/mg, P<0.05), and peripheral blood eosinophil counts tended to increase from NP alone through NP+asthma to AIA+NP group (P<0.01). Conclusion: The prevalence of subclinical AIA in patients with NP and chronic rhinosinusitis was 13.8%, and AIA was especially more prevalent in the asthmatics with NP and chronic rhinosinusitis. (Korean J Asthma Allergy Clin Immunol 2007;27:176-180)
김정순,김인환,박상순,민선양,백현욱,박주상,장은정,박상종,남기형,이성규,김현수 대한감염학회 2006 감염과 화학요법 Vol.38 No.4
목적 : 내시경 소독제 중 하나로 최근 오존수가 제시되고 있으나 국내외를 통틀어 그 연구 자료가 매우 부족하다. 이에 저자들은 오존수를 이용한 내시경 자동 세척기의 소독 효과를 알아보기로 하였다. 재료 및 방법 : 최근 구입한 내시경 한 개만을 사용하여 진단적 상부위장관 내시경을 시행 받은 환자들 중 30명을 내시경 검사 시행 후 내시경 소독법에 따라 무작위적으로 각 10명씩 3군으로 나누었다(A군, 오존수 5분 소독; B군, 오존수 10분 소독; C군, 전해산성수 3분 30초 소독). 결과 : 배양 양성률에 따라 무배양군(0 CFU/mL)과 배양군(>0 CFU/mL)으로, 배양 집락수에 따라 저배양군(<1CFU/mL)과 고배양군(≤l CFU/mL)으로 분류하였다. 내시경 선단부에서 얻은 검체의 배양 양성률은 3군 모두 0%였다. 생검겸자관 공에서 얻은 검체의 배양 양성률은 A, B, C군이 각각 70% (7/10), 70% (7/10), 90% (9/10) 이었다, 배양 집락수에 따라서는 A군에서는 고배양군에 속한 경우가 없었으나, B군에서는 30% (3/10), C군에서는70% (7/10)가 고배양군에 속했으며, A군과 C군 사이에서만 고배양률에서 유의한 차이가 나타났다(P<0.05). 결론 : 오존수를 이용한 내시경 자동 세척기는 기존의 공인된 소독제인 전해산성수와 유사한 정도의 소독력을 보여주어 내시경 소독 방법 중의 하나로 고려할 수 있다고 생각된다. Background : The aim of this study is to evaluate the effectiveness of automated ozonated water endoscopic reprocessing system (AORS). Materials and Methods : Thirty cases were collected and randomly assigned to 3 groups according to the disinfection methods (Group A, AORS for 5 minutes; Group B, AORS for 10 minutes; Group C, automated disinfection with superoxidized water for 3 minutes 30 seconds). After disinfection was finished, samples were collected from the tip of scopes (Site 1, S1) and rinsing water through biopsy channel (Site 2, S2). Samples were inoculated in blood agar plate for 48 hrs, and then colony count was evaluated. Results : Culture positive rate of S1 was 0% in all three groups. Culture positive rates of S2 were 70% (7/10), 70% (7/10) and 90% (9/10) in group A, group B and group C, respectively. High culture rate group (≥1 CFU/ml rinsing water) was 0% (0/10), 30% (3/10) and 70% (7/10) in group A, group B and group C, respectively. Disinfection efficacy between group A and C showed a significant difference in high culture rate (P<0.05). Conclusions : AORS for 5min was at least equally effective in endoscopic reprocessing compared with the conventional superoxidized water system.