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남규석(Gyu Suk Nam),이동희(Dong Hee Lee),구본승(Bon Seung Koo),권순안(Sun Ahn Kwon),대창민(Chang Min Dae),민관홍(Kwan Hong Min) 대한CT영상기술학회 2015 대한CT영상기술학회지 Vol.17 No.2
목적 : Artificial manual breathing unit bagging이 필요한 CT 검사 시 breathing circuit 사용을 통한 의료인의 피폭선량 감소 효과를 알아 보고자 한다. 대상 및 방법 : 실험에서 사용한 장비는 Brilliance iCT(256 slice MDCT, Philips healthcare, Cleveland, OH, USA), Rando anthropomorphic woman phantom (Alderson Research Laboratories inc., Stanford, USA), x-ray protective apron, x-ray protective glasses(FT-400, 범양메디칼, Korea), mobile lead glass screen(0.5 mm Pb, KYOWAGLAS-XA, KURRAY, JAPAN), mannequin, breathing circuit(산소투여용 튜브, 42inch, 에이스메디칼, Korea) 그리고 thermo-luminescence dosimeter(UD802, Panasonic, Japan)이였다. 본 연구에서는 비교실험 방법을 사용하였으며, 모든 실험은 스캐너와 근접한 위치에서 시행하였다. 방사선 방어구들을 착용하지 않은 경우를 대조군으로 정하였고 실험군들은 다음과 같다. 실험A군- 방사선 방어구들을 착용한 경우 실험B군 - 방사선 방어구들과 breathing curcuit을 사용하여 선원으로부터 42inch 멀어진 경우 실험C군 - 실험B군과 동일한 조건에서 mobile lead glass screen 사용한 경우 각 실험마다 brain CT 검사를 5회 반복하여 마네킹의 안구, 가슴 그리고 생식선의 표층 유효선량 값을 측정하였다. 결과: 1. 안구의 표층유효선량 대조군은 0.54 mSv, 실험A군은 0.16 mSv, 실험B군은 0.08 mSv, 실험C군은 0.01 mSv 였다. 유효 선량의 감소율은 대조군과 비교하여 실험A군은 약 70%, 실험B군은 약 85%, 실험C군은 약 98% 감소하였다. 2. 가슴의 표층 유효선량 대조군은 0.65 mSv, 실험A군은 0.11 mSv, 실험B군 0.01 mSv, 실험C군은 0.01 mSv 였다. 유효 선량의 감소율은 대조군과 비교하여 실헝A군은 약 83%, 실험B군은 약 98%, 실험C군은 약 98% 감소하였다, 3. 생식선의 표층 유효선량 대조군은 0.57 mSv, 실험A군은 0.12 mSv, 실험B군은 0.01 mSv, 시험C군은 0.01 mSv 였다. 유효 선량의 감소율은 대조군과 비교하여 실험A군은 약 79%, 실험B군은 약 98%, 실험C군은 약 98% 감소하였다. 결론 : Artificial manual breathing unit bagging이 필요한 brain CT 검사 시 breathing circuit 사용으로 의료인의 안구, 가슴, 그리고 생식선의 표층 유효선량 값을 각각 약85%, 98%, 98% 감소 시킬 수 있게 되었다. Purpose : The study evaluates the effect of radiation dose reduction of medical personnel in using breathing circuit during brain CT examination with artificial manual breathing unit bagging. Materials and methods: Sets of equipment used in the examinations were 256-MDCT(Brilliance iCT, Philips health care, Cleveland. OH, USA). rando anthropomorphic woman phantom(Alderson Research Laboratories inc., Stanford, USA), x-ray protect ive apron, x-ray protective glasses(FT-400, Korea), mobile lead glass screen(0.5 mm Pb, KYOWAGLAS-XA, KURRAY, JAPAN), mannequin, breathing circuit(42 inch, Korea) and thermo-luminescence dosimeter (UD802,Panasonic, Japan). A comparative experimental research method was used in the study and all experiments were conducted near the scanner. Without wearing radiation protectors was the control group and experimental groups are as follows; Group A - Wearing radiation protectors Group B - 42 inch away from iso-center by using breathing circuit and protectors Group C - Using mobile lead glass screen on group B’s condition Brain CT examinations of each experiment practiced five times to measure the surface effective dose of eyeball, breast and gonad of mannequin Results: 1. Surface effective dose of the eyeball Control group’s effective dose was 0.54 mSv. Group A, B, C showed 0.16 mSv, 0.08 mSv, 0.01 mSv respectively. The rate of effective dose of experimental groups decreased by 70%, 85%, 98% compare with the control group. 2. Surface effective dose of the breast Control group’s effective dose was 0.65 mSv. Group A, B, C showed 0.11 mSv, 0.01 mSv, 0.01 mSv respectively. The rate of effective dose of experimental groups decreased by 83%, 98%, 98% compare with the control group. 3. Surface effective dose of the gonad Control group’s effective dose was 0.57 mSv. Group A, B, C showed 0.12 mSv, 0.01 mSv, 0.01 mSv respectively. The rate of effective dose of experimental groups decreased by 79%, 98%, 98% compare with the control group. Conclusion : By using breathing circuit, effective dose reduction rate of the eyeball, breast and gonad for medical personnel decreased by 85%, 98%, 98%.
건강(乾薑)의 혈관신생(血管新生) 억제효과(抑制效果)에 관한 연구(硏究)
남상춘,강희,심범상,김성훈,최승훈,안규석,Nam, Sang-Choon,Kang, Hee,Shim, Bum-Sang,Kim, Sung-Hoon,Choi, Seung-Hoon,Ahn, Kyoo-Seok 대한암한의학회 2006 大韓癌韓醫學會誌 Vol.11 No.1
This study was conducted to investigate angiogenic inhibitory effect of Zingiberis Rhizoma methanol extract using ECV-304 cells and HT1080 fibrosarcoma cells. The viability of ECV-304 was 30% at 50${\mu}g/m{\ell}$ of Zingiberis extract and that of HT1080 was 30% at 100${\mu}g/m{\ell}$. Using the BrdU incorporation assay, Zingiberis inhibited the DNA synthesis of ECV-304 and HT1080 by 70% and 50 % at 200${\mu}g/m{\ell}$. In tube formation assay, at 10${\mu}g/m{\ell}$ of Zingiberis, tube network began to degrade and at higher doses, it was completely destroyed. Zymography demonstrated that Zingiberis extract decreased MMP-9 at 10${\mu}g/m{\ell}$ and higher doses remarkably inhibited the expression of MMP-9. These data indicate that Zingiberis Rhizoma has angiogenic inhibitory effects and shows the possibility of future anti-metastatic drug.
성찬용,류능환,연규석,윤준노,김영익,남기성,노경희,박일순 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-
본 연구는 폐석재와 석분을 사용하여 친환경적인 식생블럭 제품을 개발하기 위하여 폐석재의 입경과 석분의 첨가량을 각각 3종류씩 총 9종류의 식생블럭에 대하여 단위중량, 공극율, 투수량, 압축강도, 쪼갬인장강도, 휨강도, 내산성, 알카리농도에 대하여 구명하였다. 단위중량, 강도, 내산성은 골재의 입경이 작을수록 석분의 혼입량이 많을수록 크게 나타났으며, 공극율과 투수량은 작게 나타났다. 강도는 중성화 처리 유무에 따라 4∼5% 정도의 미소한 차이가 나타났다. 알카리 농도는 중성화 약품처리, 수중용출, 야외폭로 순으로 효과가 크게 나타났으며, 이는 식생블럭의 중성화 방법 선택에 매우 중요한 내용이라 할 수 있다. 또한, 식생상태는 공극율과 골재의 입경이 큰 식생블럭이 생육에 유리한 것으로 나타났다. This study was performed to develop the environment-friendly plantable block and to evaluate unit weight, void ratio, permeability, strength, acid-resistance and value of pH by the change of the grading of waste stone and the addition amount of stone dust. The unit weight, strength, acid-resistance is increased with small size of waste stone with increase of the addition amount of stone dust. But, the void ratio and permeability is decreased. The strength of neutral plantable block is decreased approximately 4-5% than that of the normal plantable block. The decreased effect of pH increased in order to neutral treatment, underwater leaching and field exposure. It is very important contents in neutral method selection of plantable block. Also, the planting state is grown rapidly with increase of the void ratio and of the waste stone size, approximately.
이승원,강정수,Kam Tong Leung,이원두,김동윤,한승윤,유원준,윤희정,남규석,손영규 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.43 No.-
The design of bimetallic Co–Fe oxide structures has attracted considerable research attention inmagnetic, electrochemical and catalyst materials. This paper reports the production of unique multicrystal-phase Co/Fe/CoFe2O4 by the water–gas shift reaction. The metallic Co and Fe lower the interfacialresistance, resulting in facial charge/ion transport and a dramatic enhancement in the specificcapacitance. The multi-phase Co–Fe oxide structures are also found to be applicable to the water–gasshift reaction and CO oxidation. The unique water–gas shift reaction-induced method can be very usefulto the design of highly efficient new multi crystal-phase nanostructures.
백승혁,박규주,이강영,조용범,최규석,이길연,윤상남,유창식 대한의학회 2013 Journal of Korean medical science Vol.28 No.4
There are no previous large scale studies which have evaluated the phenotypes and clinical characteristics of Korean Crohn’s disease patients who underwent intestinal resection. The purpose of this multicenter retrospective cohort study was to evaluate the clinical characteristics of Korean Crohn’s disease patients who underwent intestinal resection during the study period. A total of 686 patients were enrolled in this study. The study period was over a 20-yr period (1990-2009). The patients were divided into the first-10-yr group and the second-10-yr group. The phenotypes and clinical characteristics were compared between the groups. The most common site of the disease was the ileal area (37.8%) and stricturing behavior was observed in 38.3% patients. The most common type of surgery was segmental resection of the small bowel (30.6%). These phenotypes showed a similar pattern in both the first and second study period groups and did not show any significant differences between the groups. The number of registered patients increased continuously. The phenotypes of Korean Crohn’s disease patients who underwent intestinal resection are different compared with previously reported clinical characteristics of general Crohn’s disease patients.