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김지택,문남주,Jee Taek Kim,Nam Ju Moon 대한안과학회 2007 대한안과학회지 Vol.48 No.9
Purpose: To Carry out a low vision quality of life questionnaire and to evaluate subjective quality of life of low-vision patients. Methods: The subject were 250 patients whose visual acuity was between hand motion and 0.3 among the patients at our clinic. The normal control group included 60 patients. After a review of the literature, we selected a useful questionnaire to assess quality of life in low vision patients and translated the questionnaire into Korean. The questionnaire used had 25 items concerning low vision and each question was multiple-choice, and the sum of the total points was used to assess of the quality of life. Results: The range of scores was from 0 to 125 points (the higher the score, the higher the quality of life). Fifty-one patients among 250 patients in the low vision group replied to our questionnaire. Fifty patients among 60 patients in the control group replied. The average low vision quality of life (LVQOL) score for patients with low vision (67.3±26.7) was significantly lower than the average score of those with normal vision (114±9.72). There was no statistically significant difference between the average score of patients questioned by mail versus telephone Conclusions: The score of low vision patients was significantly lower than that of the control group, so this questionnaire can be applied to low vision patients specifically to evaluate quality of life. Optimally, the the questionnaire shoud be administered before and after the low vision consultation. The comparision of prerehabilitation score with postrehabilitation score might be helpful to evaluate the quality of life in a post rehabilitation state.
김지택,전연숙,송계용,김재찬 대한의학회 2008 Journal of Korean medical science Vol.23 No.4
Correct name of the third author of the above article is Kye Yong Song.
김지택,박종화,문남주 대한안과학회 2006 대한안과학회지 Vol.47 No.6
Purpose: To evaluate the clinical results of the auto-focusing low vision device (EYE FINE) in low vision patients. Methods: We assessed the clinical effect after prescription of the device in 21 patients who visited the low vision clinic from July 2004 to January 2005. We examined visual acuity and contrast sensitivity before and after prescription. Results: Mean distant visual acuity increased from 1.00±0.30 LogMAR to 0.69±0.34 LogMAR and the differences were statistically significant (P
The Effects of Alcohol on Visual Evoked Potential and Multifocal Electroretinography
김지택,윤철민,김성우,오재령,허걸 대한의학회 2016 Journal of Korean medical science Vol.31 No.5
The aim of this study was to investigate the acute effects of ethanol administration on pattern-reversal visual evoked potential (VEP) and multifocal electroretinography (mfERG). Fifteen healthy subjects with no ocular or general disease were recruited. VEP (0.25° pattern sizes) and mfERG with 19 elements in two recording segments were performed before ethanol administration to obtain baseline for each participant. A few days later, the participants visited again for VEP and mfERG measurements after ethanol administration. Ethanol (0.75 g/kg) was administered orally over the course of 30 minutes. VEP and blood alcohol concentration were evaluated one hour after ethanol administration, and mfERG was conducted after pupil dilation. The Wilcoxon signed-rank test was used to compare parameter changes after randomized eye selection. The mean blood alcohol concentration was 0.034% ± 0.05% by volume. VEP revealed a P100 latency delay (109.4 ± 5.3; 113.1 ± 8.2; P = 0.008) after alcohol administration. The P1 implicit time of ring 1 on mfERG showed a trend of shortening after alcohol administration (37.9 ± 1.0; 37.2 ± 1.5; P = 0.048). However, the changes did not show statistical significance after Bonferroni correction. In conclusion, orally administrated ethanol (0.75 g/kg) appears to suppress the central nervous system, but it is not clear whether alcohol intake affects the retina.
김지택,최완해,조재홍,장수,김달현,구자용,정승태,Kim, Ji-Taek,Choi, Wan-Hae,Jo, Jae-Heung,Chang, Soo,Kim, Dal-Hyun,Koo, Ja-Yong,Chung, Seung-Tae 한국광학회 1999 한국광학회지 Vol.10 No.3
가열인장(heating and pulling)방법을 이용하여 개구부 직경이 약 100nm 이하인 광섬유 탐침을 제작하였으며, 이를 이용하여 일정광량 방식의 광자주사현미경을 제작하였다. 광섬유 탐침을 물체에 미세하게 접근시켜서 물체면을 주사하기 위하여 원통형 PZT(piezoelectric transducer)를 x-y-z의 3부분으로 나누어 z축의 미세접근 및 1.43$\mu\textrm{m}$ $\times$ 1.76$\mu\textrm{m}$의 면적을 x-y축으로 주사할 수 있는 3차원 PZT 주사기를 제작하였다. 그리고 광섬유 탐침에서 검출되는 에바네슨트라의 광량이 항상 일정하도록 전자적인 되먹임 회로에 의한 광섬유 탐침이 1$\lambda$ ($\lambda$ 는 입사파장임) 이하의 근접장 영역에서 물체로부터의 높이가 일정하도록 하였다. 그리고 이렇게 제작된 일정광량 모드의 광자주사 현미경을 이용하여 정상파 형태의 에바네슨트파를 측정하였다. We made sharp optical fiber tips with less than 100 nm diameter by using the heating and pulling method with a good repetition and fabricated the photon scanning tunneling microscope (PSTM) using constant intensity mode. The 3-dimensional PZT (Piezoelctric transducer) scanner made of a long PZT tube is consisted of three divided parts, that is, a pair of $\pm$ x and a pair of $\pm$y scanning parts and a z scanning part for the fine approach and scanning. The scanning dimension is 1.43 $\mu\textrm{m}$$\times$1.76 $\mu\textrm{m}$. The height of a optical tip to maintain a constant height within $1/{\lambda}_0$ (${\lambda}_0$ is the incident wavelength) from surface of a specimen to a optical tip is controlled automatically by using the electric feedback circuit. The 3-dimensional shape of standing evanescent waves generated on the surface of a dove prism was measured successfully by using the constant intensity mode PSTM.
김지택,Yeoun Sook Chun,송계용,Jae Chan Kim 대한의학회 2008 Journal of Korean medical science Vol.23 No.3
We report our experience with corneal epithelium, grown in vivo, transplantation in three patients with persistent epithelial defect (PED). The three patients had ocular surface disease unresponsive to standard treatments and were therefore chosen for transplantation. They underwent transplantation of epithelial sheets, grown in vivo, to the most affected eye. In vivo cultivation was carried out in the cornea of a living related donor. After epithelialization was completed, the epithelium grown on an amniotic membrane was harvested gently; it was then transplanted into the patient’s eye after debridement of fibrovascular tissue. The cultivated epithelium was completely epithelialized by 2 weeks; it was well-differentiated with well-formed hemidesmosome. On immunohistochemical staining, p63, connexin 43, and Integrin β4 were expressed in the cells on the epithelial sheet. The PED was covered completely and maintained for 4 weeks in all cases. However, corneal erosion recurred after 5 weeks in two cases. This novel technique demonstrates the corneal epithelial cells can be expanded in vivo successfully on denuded amniotic membrane of a healthy cornea and harvested safely. A corneal epithelial sheet, grown in vivo, can be transplanted to treat eye with a severe ocular surface disease, such as total limbal deficiency.