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항정신병약물에 의한 안구운동발작과 발작성 지각변화 증후군
정인원,김임열,윤탁,정성훈,정희연,김용식 대한조현병학회 2018 대한조현병학회지 Vol.21 No.1
During antipsychotic drug treatment, clinicians occasionally encounter sudden attacks of oculogyric crisis (OGC) and/or paroxysmal perceptual alteration (PPA) which occur mostly in the afternoon or early evening lasting for minutes to hours and are eventually remitted with rests or short sleep and/or medications such as benzodiazepines, anticholinergics and so forth. Moreover, these attacks are usually accompanied with psychiatric symptoms such as various modalities of hallucinations and illusions, delusions, obsessive thoughts, panic attacks, agitation as well as autonomic symptoms. These accompanying psychiatric symptoms can be perceived as a worsening of psychiatric symptoms if the clinician does not understand the symptoms due to the side effects of antipsychotic drugs, which may result in increasing the dosage of antipsychotics instead of reducing doses or switching to less offending drugs. On the other hand, patients could easily recognize the symptoms as the adverse effects of drugs. This literature review and case-series study is aimed to raise awareness of OGC and PPA by providing clinical cases and author’s views with the literature reviews about concepts, recognitions and managements from the works of Japanese authors who first reported the clinical importance of these attacks, particularly PPA.
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정인원,정성훈,김임열,윤탁,김세현,김용식 대한신경정신의학회 2016 신경정신의학 Vol.55 No.4
Soliloquy is a significant symptom in schizophrenia and is usually regarded as being related to auditory hallucination. Elucidation of the psychopathology of soliloquy is incomplete. Soliloquy is also a normal human behavior that has multidimensional functions such as guiding internal cognitive processes and managing social interaction. In the young, soliloquy appears as egocentric speech and arises before maturation of the third-person perspective. Soliloquy has been regarded as indicative of an intermediary stage during the transformation of social speech into internalized thinking. Every thought process retains a social dimension because language itself is based on intersubjectively shared meanings, and internal thinking originates from interpersonal communication. Thus, soliloquy can be seen as a kind of thought process that accentuates the social dimension. This approach may help in understanding soliloquy in normal and pathological situations. Soliloquy was actively discussed in the late nineteenth and early twentieth century in European psychiatry. Since then it has received less attention and has been neglected as an academic concern, except in child developmental theory. Recently however, soliloquy has attracted more attention among neuroscientific researchers. To attain an advanced understanding of soliloquy, it is necessary to integrate the early European perception of soliloquy with current developmental theory. In this paper, we review past literature on the conceptualization of soliloquy and integrate those concepts into an explanatory framework. In addition, a case series and a discussion of the applicability of the explanatory framework are presented. Our results may help provide an insight into the contemporary understanding of soliloquy.
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