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수도권 일부 초등학교 고학년 학생의 구강보건에 관한 지식과 태도, 행동의 상관성 연구
김석환,김재홍,김지환,Kim, Seok-Hwan,Kim, Jae-Hong,Kim, Ji-Hwan 대한치과기공학회 2011 대한치과기공학회지 Vol.33 No.4
Purpose: The purpose of this study was to obtain data that can be utilized in the planning of oral health education plan, by surveying the correlation between oral health knowledge, attitude, and behavior among high grade students elementary school in some regions of the metropolitan. Methods: The subject of this study through the survey of the recognition of the oral health, a questionnaire survey was conducted for 548 male and female students who were in the 4th, 5th, 6th grade of elementary school in some regions of the metropolitan. Statistical analysis was conducted using the SPSS 12.0 with t-test, ANOVA, and correlation. Results: Knowledge of oral health was very high. Correct attitudes and positive behavior were indicated. There was a significant difference in oral health knowledge according to school year and parents' dental condition(P<.05). The student one recording oral health behavior degree where the oral health knowledge is high appears highly, considers statistically the difference which it was visible. Positive correlation was significantly observed among oral health knowledge, attitudes, and behavior. Especially, attitudes and toothbrush method were highly correlated(r=.853). Conclusion: Oral health program through the elementary school students and their parents for the development of proper oral health care education programs continue to be made should be considered.
부분 체중지지를 이용한 앞, 뒤로 걷기 운동이 불완전 척수손상환자의 보행에 미치는 효과
김석환,정재훈,Kim, Seok-Hwan,Chung, Jae-Hoon 대한고유수용성신경근촉진법학회 2011 PNF and Movement Vol.9 No.2
Purpose : The purpose of this study was to find out of an effect of forward, backward walking using partial weight bearing on walking of the patient with incomplete spinal cord injury. Methods : The average age, and the term of being sick of 6 patients who were selected as the subjects with incomplete spinal cord injury and who received medical attention in the National Rehabilitation Hospital, was 50.3 years old, and 10.7 months, and those were also the patients that were classified as ASIA-C or D by ASIA. The forward, backward walking using a partial weight bearing system as the research method, took total 6 weeks, 3 days per week, 3 times per day, total 45 minutes for each time(15 minutes for a time, 5 minutes for a breathing time), and the 15 minutes was used for forward walking 7.30 minutes, backward walking for 7.30 minutes, to find out before and after the test of WISCI, PCI, Walking Speed, Motor Score of Lower Limbs for the selected patients with incomplete spinal cord injury. Results : The result was showed WISCI from 17 points to 17 points that is, no change occurred at all, and PCI from $161.01{\pm}103.06$ to $74.97{\pm}58.19$, some amount of reduction that is not statistically significant(p<.05). Regarding walking speed, it increased from $24{\pm}.07m/sec$ to. $61{\pm}.35m/sec$, that is statistically significant(p<.05), and motor score of lower limbs showed statistically significant increase like from $33.17{\pm}7.08$ to $37{\pm}5.14$(P<.05). Conclusion : The 4 evaluation categories seem to have shown differences due to an insufficient number of subjects, and short test term, and it seems the more diverse task-oriented walking exercises should be studied in the coming days.
Streptozotocin 유도 당뇨성 흰쥐에서 methotrexate의 신독성 생성기전에 관한 연구
김석환,김여정,이주연,강혜옥,이항우,최종원,Kim Seok-Hwan,Kim Yeo-Jeong,Lee Joo-Yeon,Kang Hye-Ok,Lee Hang-Woo,Choi Jong-Won 한국생명과학회 2006 생명과학회지 Vol.16 No.2
엽산과 유사한 구조를 가져 관절염 치료제로 쓰이는 methotrexate (MTX)의 당뇨병 쥐에서의 신독성 기전을 구명할 목적으로 실험동물 정상군과 STZ로 당뇨를 유발한군에 MTX률 투여하여 신장 독성을 유발하여 혈중 생화학적 변화를 관찰하고 free radical의 생성계와 해독계의 활성에 미치는 영향을 관찰하였다. 혈중 신장기능 지표 효소 및 신장조직의 지질과산화 함량이 정상군에 MTX를 투여한 군에 비해 당뇨쥐에 MTX를 투여한 군에서 현저히 증가하였다. 당뇨쥐에 MTX를 투여함으로써 활성산소 생성계인 phase I 단계 중 cytosol 효소계 활성이 정상쥐에 MTX를 투여한 군에 비하여 현저히 증가하였고, phase II 단계 중 glutathione S-transferase의 활성이 정상쥐에 MTX를 투여하였을때에 비하여 당뇨쥐에 MTX를 투여하였을때 현저히 감소하였다. 신조직 중 glutathione의 함량 또한 당뇨쥐에 MTX를 투여했을때 현저히 감소하였고 이러한 결과는 $\gamma$-glutamylcysteine synthetase와 glutathione reductase의 활성을 감소시킨 결과로 생각된다. 이상의 결과를 종합하여 볼때 당뇨쥐에 MTX를 투여하면 신독성이 증가함을 확인할 수 있었고, 그 기전은 cytosol계 효소 활성을 증가시켜 MTX의 대사계를 촉진시킴으로 독성물질의 생성을 증가시키고, 이로 인한 신조직중의 지질과산화 함량의 증가는 glutathione의 함량 감소에 의해 나타나는 결과로 사료되어진다. This study is investigated the effect on mechanism of nephrotoxicity formation of methotrexate(MTX) by hyperglycemic by streptozotocin(STZ). MTX was injected daily at two doses of 3, 6 mg/kg for 1 week in STZ-induced hyperglycemic rats. Activities of BUN, creatinine and LDH were significantly increased by treatment with MTX in STZ-induced diabetic group when compared to MTX treatment group in normal rats' Renal lipid peroxide content and activities of cytosolic enzyme were significantly increased in the treatment of MTX in diabetic group. The concentration of glutathione and glutathione biosynthesis enzymes were decreased by treatment with MTX in STZ-induced diabetic group. These results suggest that nephrotoxicity of MTX in STZ-induced hyperglycemic rat was caused by activation of renal metabolizing enzymes in cytosol and decrease of glutathione concentration.
딥러닝 기반 보도(步道) 환경 인식 및 쓰레기 분류 기술을 탑재한 청소로봇 시스템
이종수 ( Jong-soo Lee ),임경민 ( Kyeong-min Lim ),이영민 ( Young-min Lee ),임준오 ( Jun-oh Lim ),양우성 ( Woo-sung Yang ) 한국정보처리학회 2022 한국정보처리학회 학술대회논문집 Vol.29 No.2
본 논문에서는 자율주행을 통해 보도를 청소하는 동안 분실물을 인지할 수 있는 로봇 시스템을 개발하였다. 분실물의 종류는 딥러닝 모델에 의해 지정되고 학습되며 로봇은 이를 인식하여 저장한다. 보도 경계 및 장애물을 감지하기 위해 Image-Segmentation 기술을 사용하였으며, 물체 감지에 사용되는 depth 카메라(d435)를 사용하였다. 학습하기 위한 딥러닝 모델로 YOLOv5 를 사용하였으며, 그 결과 정해진 사물을 인식하는 데 평균 84%의 정확도를 보였다. 이 시스템을 로봇에 적용할 경우 예상되는 효과로는 정확한 보도 인식으로 로봇이 경로를 이탈하지 않도록 하는 것, 유실물품의 신속하고 안전한 인계 등이 있다.