http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 김명석(Myung Sook Kim) (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
-
박종완(Jong-Wan Park),전양숙(Yang-Sook Chun),김명석(Myung-Suk Kim) 대한약리학회 1996 대한약리학잡지 Vol.32 No.2
Restoration of the blood flow after a period of ischemia is accompanied by generation of toxic oxygen radicals. This phenomenon may account for the occurrence of reperfusion-mediated tissue injury in ischemic hearts. In in vitro studies, although oxygen radicals can be generated from a variety of sources, including xanthine oxidase system, activated leucocytes, mitochondria and others, the most important source and mechanism of oxygen radical production in the post-ischemic reperfused hearts is unclear. In the present study, we tested the hypothesis that the respiratory chain of mitochondria might be an important source of oxygen radicals which are responsible for the development of the reperfusion injury of ischemic hearts. Langendorff-perfused, isolated rat hearts were subjected to 30 min of global ischemia at 37˚C, followed by reperfusion. Amytal, a reversible inhibitor of mitochondrial respiration, was employed to assess the mitochondrial contributions to the development of the reperfusion injury. Intact mitochonria were isolated from the control and the post-ischemic reperfused hearts. Mitochondrial oxygen radical generation was measured by chemiluminescence method and the oxidative tissue damage was estimated by measuring a lipid peroxidation product, malondialdehyde(MDA). To evaluate the extent of the reperfusion injury, post-ischemic functional recovery and lactate dehydrogenase(LDH) release were assessed and compared in Amytal-treated and -untreated hearts. Upon reperfusion of the ischemic hearts, MDA release into the coronary effluent was markedly increased. MDA content of mitochondria isolated from the post-ischemic reperfused hearts was increased to 152% of preischemic value, whereas minimal change was observed in extramitochondrial fraction. The generation of superoxide anion was increased about twice in mitochondria from the reperfused hearts than in those from the control hearts. Amytal inhibited the mitochondrial superoxide generation significantly and also suppressed MDA production in the reperfused hearts. Additionally, Amytal prevented the contractile dysfunction and the increased release of LDH observed in the reperfused hearts. In conclusion, these results indicate that the respiratory chain of mitochondria may be an important source of oxygen radical formation in post-ischemic reperfused hearts, and that oxygen radicals originating from the mitochondria may contribute to the development of myocardial reperfusion injury.
-
정을순(Eul Soon Chung),이상종(Sang Jong Lee),이만호(Man Ho Lee),오동주(Dong Joo Oh),안현택(Hyun Taek Ahn),주영만(Young Man Joo),김명석(Myung Sook Kim) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1
In 1960 Matein first described an unusual type of smooth muscle tumor of the stomach and 1962 Stout found the each tumor microscopically consisted of round or polygonal cells frequently containing of perinuclear vacuole or clear zone instead of the usual spindle cells as seen in the common leiomyoma and addressed this intramural tumor as a leiomyoblastoma. Since Stout reported a series of 69 cases, many clinical studies on this tumor have been published. In Korea Oh et al first reported a case of leiomyoblastoma of stomach in 1973 and thereafter two cases have been reported to date. 43-year-old housewife was admitted to this hospital because of dull pain on epigastrium and left upper abdomen with duration of two days last october 1985. Her condition was suspected as mesenteric cyst probably arising between stomach and pancreas. Whereas, surgery of the mass proved as epitheloid leiomyoma of stomach. As leiomyoblastoma has different clinical behavior and prognosis from leiomyosarcoma, special attention should be paid to this relatively rare tumor.
-
비타민 B군을 함유한 균형 영양을 섭취시킨 불면증, 우울증, 정신분열증 환자들에 관한 사례 연구
송숙자,김명석 한국정신과학학회 2002 韓國精神科學學會誌 Vol.6 No.1
Health, as defined by the Word Health Organized, is a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity. Everybody wants to have healthy and long life To maintain the healthy life it is necessary for human beings to have sufficient food, good nutrition balanced in daily lives. Everyone's healthy condition differs according to the nutrition taken by himself, the food quality everybody recognizes the fact that good life style is useful for health, It is not easy to get rid of such harmful behaviors and customs leading to bad health. Of course, as human's physical condition can be differed by sex, age, life style and diet, modern human's health standard would be differed according to their nutritious conditions The criteria for the modern human health depends on their nutritious condition very differently Therefore, the purpose of this study was to investigate the difference between well-balanced nutrition and unbalanced nutrition for Insomniac, melancholiac, schizophrenic patients, All 6 of Insomniac, melancholiac, schizophrenic patients were selected for this study five of them was cured, but one was not recovered. that is, when they take balanced nutrition and vitamin B group without using special medicine, they could recover melancholi and schizo. but when they didn't keep a good lifestyle, they began to suffer from melancholi and schizo again.
ScienceON연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
