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權國賢,孫敬植,具本天,尹榮佶 慶北大學校 醫科大學 1976 慶北醫大誌 Vol.17 No.1
慶北醫大附屬病院 內科에서 診療한 糖尿病 惠者 524例에서 初診時에 取한 心電圖를 分析하여 이들 所見을 健康人 200例에서 얻은 그것과 比較檢討하여 다음과 같은 成績을 얻었다. 1) 糖尿病 患者의 心電圖 所見은 健康人群의 그것보다 異常所見의 發生 頻度가 뚜렷이 높았으며 특히 各種 不整脈, 房室傳導障碍, 左側軸偏位, 左心室肥大, Q-T間隔延長 및 ST,T變化 所見은 더욱 뚜렷한 差異를 보였다. 2) 心電圖 異常 所見은 心血管疾患을 合倂한 例에서 뚜렷이 많았으며 心血管疾患이 없는 患者에서도 健康人에서 보다 높은 頻度의 異常所見을 볼 수 있었다. 3) 網膜症 有無에 따른 心電圖 異常 所見의 頻度는 網膜症이 있는 群에서 그 頻度가 뚜렷이 높았다. 4) 病歷 期間에 따른 心電 圖異常 所見의 頻度는 그 期間이 길수록 增加하는 傾向이 顯著하였으며 房室 block을 除外한 各種 不整脈, 心室內傳導障碍, 左側軸偏位, 左心室肥大, 心筋梗寒, Q-T間隔延長 및 ST,T變化등에서 뚜렷한 差異가 있었다. 5) 空腹血糖値와 心電圖 異常所見의 頻度 사이에는 一定한 相關性이 없었으나 血中 cholesterol値와의 사이에는 그 値가 높은 群에서 그 頻度가 높은 傾向을 보였다. Electrocardiograms obtained from 524 cases of diabetics on their first clinic visit at the department of medicine, Kyungpook National University Hospital were analyzed and a comparision of the results was made to those recorded on 200 apparently healthy persons. As expected, the incidence of abnormal electorcardiograms was considerably higher in the diabetics particularly in those with cardiovascular complications, arteriosclerotics, hypertensive and/or diabetic retinopathy, hypercholesterolemia, and longstanding illness. The major abnormal findings were prolongation of Q-T interval, left ventricular hypertrophy, ST, T change, left axis deviation, atrioventricular conduction defect and mechanism disorder, in the order of frequency. However, no relationship was noted between the levels of fasting blood sugar and the incidence of abnormal electrocardiograms.
各種 病原菌의 Josamycin^� 및 몇가지 抗生劑에 대한 感受性에 관하여
全在殷,權國賢,權寧輳,李長白 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.16 No.1
Sensitivity tests to Josamycin(JM), a new macrolide antibiotic, and several other antibiotics in common clinical use were done by the disc plate method on 61 strains of pathogens isolated from patients with various infections. Pathogens subjected to the tests were staphylococcus aureus, streptococcus hemolyticus, diplococcus pneumoniae and enterococcus. Other antibiotics tested were chloromycetin (CM), erythromycin(EM), kanamycin(KM), penicillin-G(PC), streptomycin (SM) and tetracycline(TC). All strains of diplococcus pneumoniae were sensitive to JM and four out of 15 strains of alpha-hemolytic streptococci were resistant to JM. Five out of six strains of enterococci were sensitive to JM. Nearly all strains of staphylococcus aureus and beta-hemolytic streptococci were sensitive to JM: only one out of 25 strains being resistant in the former and one out of 11 strains in the latter, respectively. These results suggested that JM was a dependable drug for the control of various infections caused by these organisms. Staphylococcus aureus was more sensitive to JM than CM, KM, PC, SM, and TC. Its sensitivity to JM was comparable to that of EM. Hemolytic streptococci were almost equally sensitive to JM, EM, PC or TC but less so to CM, KM, and SM. Sensitivity of diplococcus pneumoniae to JM, PC, and EM was comparable. Enterococci were more sensitive to JM and PC than to the other antibiotics tested. Almost all strains of staphylococcus aureus resistant to all the non-macrolide antibiotics tested were sensitive to JM. Thus, it seemed that cross-resistance of organisms to JM with other antibiotics was not a problem of clinical significance in the treatment of staphylococcus aureus infection and JM was a reliable drug for this infection.