아마인유와 해바라기종자유의 혼합급이가 고지혈증 흰쥐의 신장지질의 지방산조성에 미치는 영향

강진순 진주여자전문대학 1994 論文集 Vol.17 No.-

This study was carried out to investigate the effect of feeding the mixture of linseed oil, rich in n-3 PUFA and the sunflower seed oil, rich in n-6 PUFA on the fatty acid composition in the dietary hyperlipidemic rats. After Male Sprague Dawley rats were induced hyperlipidemia by feeding the diet containing lard, butter and cholesterol for 3 weeks, then they were fed with the diet containing lard 3.0% and sunflower seed oil and antihyperlipidenmic drugs for 2 weeks. Analysis of the lipid and the fatty acid composition of the kidney lipid showed following results. In the total fatty acid contents of kidney lipids, monoenes were remarkedly lower than saturates and polyenes, while there were not significantly different among total diet groups. As compare to fatty acid contents of test lipid feed hyperlipidemic rats, Saturates and polyenes in the total fatty acid contents were increased, on the contrary, monoenes were getting significantly decreased In the fatty acid composition of phospholipid in kidney, polyenes contents were the most among all of them, especially C_(20:5)(n-5) was the major fatty acid. In the fatty acid composition of TG and cholestrryl ester, monoenes and saturates content were similar, but polyenes content were remarkedly low as 7.0-25.8% since C_(20:0), C_(22:5)(n-6), C_(22:5)(n-6), C_(22:6)(n-3) were not distributed Polyenes contents of group 5-9 feed mixed linseed oil and sunflower oil were getting higher than group 1-4 feed butter or olive oil in the TG and cholesteryl ester, and it seems to be affected by the fatty acid composition of the test lipids. C_(20:5)(n-3) was the major fatty acid and PL, while C_(18:2)(n-6) was the major fatty acid in TG and cholesteryl ester of kidney lipid Each lipid composition was comparatively influenced by test lipid rather than cholestyramine and antihyperlipidemic dose. Sunflower seed oil and linseed oil were effective for the improvement of kidney lipids.

아마인유와 해바라기 종자유의 혼합급이가 고지혈증 흰쥐의 비장 지질의 지방산조성에 미치는 영향

강진순 진주여자전문대학 1995 論文集 Vol.18 No.-

This study was carried out to investigate the effect of the feeding mixture of linseed oil, rich in n-3 PUFA and the sunflower seed oil, rich in n-6 PUFA on the fatty acid composition in the dietary hyperlipidemic rats. Afterr Male Sprague Dawley rats were induced hyperlipidemia by feeding the diet containing lard, butter and cholesterol for 3 weeks, then they were fed with the diet containing lard 3.0% and butter 12.0% for control, the mixture in different proportion of both linseed oil and sunflower seed oil and antihyperlipidemic drugs for 2 weeks. Analysis of the lipid composition and the fatty acid composition of the spleen lipid showed following results. In the total fatty acid contents of spleen lipids, saturates was remarkedly more than monoenes and polyenes, while there was not significant different among total diet groups. Polyenes of the total fatty acid was not distributed C_(18:2), C_(18:3) on test lipid, but it was distributed on C_(20:4)(n-6), C_(20:5)(n-3), C_(22:6)(n-3) on spleen tissue feed hyperlpidemic rats. In the fatty acid composittion of phospholipid in spleen, polyene contents of group 1-4 feed test lipid were 5.5-7.3% but increased to 26.0-36.3% in spleen lipid of hyperlidemic rats. In the fatty acid composition of triglyceride, polyene contents of group 5-9 feed test liplld were 59.1-62.3% but decreased 17.0-22.4% in spleen lipid of hyperlippidemic rats, on the contrary, polyene contents of group 1-4 feed test lipid were 5.5-7.3% but increased to 11.5-20.3% in spleen lipid of hyperlipidemic rats. In the polyenes, TG content of group 5-9 feed mixed linseed oil and sunflower oil was getting higher than group 1-4 feed butter or olive oil and it seems to be affected by the fatty acid composition of the test lipids. In the fatty acid composition of CE were remarkedly significant different among monoenes, saturates and polyenes in test lipid but it was different tendency in spleen lipid of hyperlippidemic rats. C_(20:5)(n-3) was the major fatty acid in total fatty acid and PL, while C_(18:2) (n-6) was the major fatty acid in TG and CE of spleen lipid. Each lipid composition was comparatively influenced test lipid rather than cholestyramine and antihyperlipidemic dose. Sunflower seed oil and linseed oil were effective for the improvement of spleen lipids.

보리새우 乾製品의 맛成分 (1) : 遊離 아미노酸에 關하여 On free amino acid contents

姜晉順,金成姬,鄭承鏞,禹永淑 진주여자전문대학 1985 論文集 Vol.7 No.-

This study was made to analysis of taste compounds in extracts which may participate in flavor and taste, in dried Prawn. Penacus japonicus. The changes of such compounds during sun during as free amino acids were analyzed. The results are summarized as follows : Among the free amino acids analyzed, glycine, arginine, proline, taurine and alanine were found in large amounts in the raw extracts, the amount of valine, methionine, isoleucine, leucine and tyrosine were low. The free amino acids were not changed in composition but the decrease of total free amino acid was approximately 588 mg% during sun during. In sun dried prawn, glycine, arginine, taurine, proline and alanine were abundant too.

아마인유와 해바라기 종자유의 혼합급이가 고지혈증 흰쥐의 폐조직 지질의 지방산조성에 미치는 영향

강진순 진주여자전문대학 1997 論文集 Vol.20 No.-

This study was carried out to investigate the effect of the feeding mixture of linseed oil, rich in n-3 PUFA and the sunflower seed oil, rich in n-6 PUFA on the fatty acid composition in the dietary hyperlipidermic rats. After Male Sprague Dawley rats were induced hyperlipidermia by feeding the diet containing lard, butter and cholesterol for 3 weeks, then they were fed with the diet containing lard 3 0% and butter 12 0% for control the mixture in different proportion of both linseed oil and sunflower seed oil and antihyperlipidermic drugs for 2 weeks. Analysis of the lipid composition and the fatty acid composition of the lung lipid showed following results. In the total fatty acid contents of lung lipids, saturates were remarkedly more than monoenes and polyenes, while there were not significant different among total diet groups. Polyenes of the total fatty acid were not distributed C_(18:2), C_(18:3) on test lipid. but it were distributed on C_(20:4)(n-6), C_(20:5)(n-3), C_(22:5)(n-3), C_(22:6)(n-3) on lung tissue feed hyperlpidermic rats. In the fatty acid composition of phospholipid in lung, polyene contents of group 1-4 feed test lipid were 5.5 - 7.3% but increased to 25.7 - 28.9% in lung lipid of hyperlidermic rats In the fatty acid composition of triglyceride, TG content of group 5-9 feed mixed linseed oil and sunflower oil were getting higher than group1-4 feed butter or olive oil and it seems to be affected to anti-atherosclerosis. In the fatty acid composition of C E were remarkedly significant different among monoencs, saturates and polyenes in test lipid but it was different tendency in lung lipid of hyperlipidermic rats C_(20.5)(n-3) was the major fatty acid in total fatty acid and PL while C_(18.2)(n-6) was the major fatty acid in total fatty acid, TG and C E of lung lipid Each lipid composition was comparatively influenced test lipid rather than cholestyramine and antihyperlipidermic dose. Sunflower seed oil and linseed oil were effective for the improvement of lung lipids.

생약복합물이 흰쥐의 항산화 및 인지개선활성에 미치는 영향

강진순 한국식품영양학회 2016 한국식품영양학회 학술대회논문집(학술심포지움) Vol.2016 No.06

타부처와의 벅찬 싸움에서 밀리는 환경처 - 환경처위상 재정립은 요원한가

강진순 한국환경기술인연합회 1991 환경기술인 Vol.58 No.-

Vitamin C가 방사선과 Aflatoxin B1을 투여한 흰쥐 간세포의 항산화효소 및 Stress Protein에 미치는 영향

강진순 한국식품영양학회 2015 한국식품영양학회 학술대회논문집(학술심포지움) Vol.2015 No.12

Vitamin C가 방사선과 Aflatoxin B1을 투여한 흰쥐 혈청 중의 항산화효소 및 혈액성분에 미치는 영향

강진순 한국식품영양학회 2015 한국식품영양학회 학술대회논문집(학술심포지움) Vol.2015 No.12

미술교육에서 오감 경험을 통한 조형놀이가 학습 성과에 미치는 영향에 관한 연구

강진순 한국초등미술교육학회 2002 미술교육연구논총 Vol.13 No.1

생약복합물이 흰쥐의 체내에서 항산화 및 인지개선활성에 미치는 영향

강진순,Kang, Jin-Soon 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.3

인지기능 활성을 가진 생약복합물을 선정하여 최적조성물을 조제한 다음, 생약복합물의 첨가비율을 달리하여 치매유도 동물모델에서 항산화 효과와 인지기능 개선을 확인한 결과는 다음과 같다. 1. 20일간 사육한 흰쥐 혈청의 GOT, GPT, creatinine 및 BUN 활성을 측정한 결과, 생약복합물을 투여한 군(3, 4군)이 정상군(1군)에 비해 GOT 농도는 감소하였고, GPT 농도와 Creatinine 농도는 유의적인 차이는 없었다. BUN 농도는 정상군(1군)에 비해 생약복합물을 투여한 군(3, 4군)이 유의적으로 감소하였다. 2. 혈액 중의 총 콜레스테롤과 HDL-cholesterol은 유의적인 차이가 없었으나, 중성지방은 전군에서 정상군(1군)에 비해 치매유발군인 2군이 낮았고, 생약복합물 투여군(3, 4군), 치매치료군(5군)은 가장 낮았으며, 이들 군 간에는 유의적인 차이는 없었다. 3. 혈액 SOD 활성은 정상군(1군), TMT 투여군(2군) 및 tacrine 투여군(5군) 간에는 유의적인 차이가 없었으나, 생약복합물 투여군(3, 4군)이 다소 높아 유의적인 차이를 나타내었다(p<0.05). MDA 함량은 정상군인 1군과 치매치료군인 5군이 치매유발군인 2군과 생약복합물 투여군(3, 4군)에 비해 유의적으로 높았으며, 2, 3, 4군 간에는 유의적인 차이가 없었다. 4. AChE 활성은 TMT로 치매를 유발한 2군이 가장 높았으며, 치매치료군(5군)은 정상군(1군)의 수준으로 가장 낮게 나타났다. 그리고 생약복합물을 투여한 3군, 4군에서는 유의적 차이는 없으나, TMT로 치매를 유발한 2군보다는 유의적으로 감소하였고(p<0.05), 치매치료군인 5군보다는 다소 높게 나타났다. 5. 단기기억능력을 시험하기 위한 Y-maze를 실시한 결과는 Y-maze의 각 arm을 통과한 총 횟수는 전군에서 유의적인 차이는 없었다. 교차행동력은 TMT 투여군인 2군이 가장 낮았으며, 치매치료제인 tacrine을 투여한 5군이 가장 높아 5군(tacrine 투여)은 TMT 투여군인 2군에 비해 약 125% 현저한 기억력 증가를 보였다. 이에 반해 생약복합물 투여한 2, 3군은 정상군과 유의적인 차이가 없었으나, TMT 투여군인 2군에 비해 각각 117.32%와 120.38% 수준으로 기억력 증가를 보였다. 장기기억능력을 시험하기 위한 수동회피실험의 결과, TMT 투여군(2군)은 전군에서 가장 낮았으나, 생약복합물 중, 고용량 투여군(3, 4군) 및 tacrine 투여군은 증가하였고, 특히 고용량(4군)에서 유의성 있는 증가를 나타내어(p<0.05) 정상군에 가깝게 회복시켜 주는 경향을 보여 주었다. 이상의 결과를 통하여 생약복합물은 치매 유발 동물모델의 항산화능의 저하를 억제하고, AChE 활성을 억제하여 ACh의 활성을 촉진하므로 장 단기 기억능력의 회복 및 개선효과를 확인할 수 있었다. 그러나 향후 생약복합물의 농도에 따른 첨가군을 확대하여 인지기능 개선에 가장 효과적인 최적농도를 도출하는 연구가 계속 진행되어야 할 것으로 사료된다. The purpose of this experiment was designed to investigate the effects of medicinal herbs (MH) extracts on dementia induced by trimethyltin chloride (TMT) in rats. Six-week-old male Sprague-Dawley rats were randomly divided into five groups; normal group (group 1), control group (group 2), MH extracts group (250, 500 mg/kg) (group 3, group 4) and positive control group (tacrine group, group 5). In the control group to induce dementia, a 2.5 mg/kg of TMT intraperitoneal injection was used for 14 days (1 per day) in the rats. In the MH extracts group 250 mg/kg and 500 mg/kg of MH extracts were medicated in an oral inoculation for 20 days (1 per day). After 30 minutes, a 2.5 mg/kg of TMT intraperitoneal injection, which causes dementia, was used for 14 days (1 per day). In the positive control group (Tacrine group) 10 mg/kg of Tacrine, the dementia treatment, was medicated in an oral inoculation. After 30 mintues, 1 mg/kg of TMT intraperitoneal injection, which causes dementia, was used for 14 days (1 per day). The present author observed the passive avoidance performance test, and memory ability test (Y maze test), the values of MDA, acetlycholinesterase (AchE) activity in the brain and antioxidant enzyme in serum. MH extracts significantly improved memory of AD model rats in the Y-maze test, and also significantly improved memory of AD model rats in the passive avoidance test. MH extracts significantly reduced AChE activity, and significantly increased the SOD level, but not catalase and MDA. From the results above, MH extracts is thought to be effective in the improvement of antioxidant enzymes and memory ability.