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김일용 한국약제학회 1980 Journal of Pharmaceutical Investigation Vol.10 No.3
A study on the diuretic action of Siegesbeckiae herba in dogs was made using a clearance technique with ethanol extract. Siegesbeckiae herba ethanol extract (SGEE) administered intravenously in doses 6.0 and 60.0㎎/㎏ elicited diuresis and an increase in sodium and potassium excretion, and it simultaneously produced a decrease in the reabsorption rate of sodium and potassium in renal tubules. Neither renal plasma flow nor glomerular filtration rate changed significantly. SGEE, when infused directly into a renal artery in doses of 0.5 and 1.5㎎/㎏ min, exhibited identical results to the intravenous responses confined only to the infused kidney. The above observations lead to the suggestion that SGEE elicits diuresis in dogs by decreasing the reabsorption rates of sodium and potassium in renal tubules.
金日龍,殷鍾瑩,高錫太 조선대학교 약학연구소 1982 藥學硏究誌 Vol.4 No.1
Choryongdamsagan-Tang water extract(CWE), when given intravenously, produced hypotensive action in rabbit. The hypotensive action induced by CWE was inhibited by pretreatment of atropine, anticholinergic agent, and diphenhydramine, antihistamines, but potentiate by pretratment of physostigmine, cholinesterase inhibitor. The hypotensive action induced by CWE was not influenced by bethanidine, sympathetic blocking agent, chlorisondamine, autonomic ganglionic blocking agent, and propranolol, sympathetic beta blocking agent. The CWE did not affect the pressor actions caused by norepinephrine, sympathetic alpha receptor stimulant and carotid artery occlusion. Above results suggest that CWE produce the hypotensive action through muscarinic action and histnmine like action.
CaO-SiO<sub>2</sub>-PEEK 생체복합체의 제조와 in-vitro 특성평가
김일용,조성백,김종옥,신종우,이성호,박중근,김택남,Kim Ill Yong,Cho Sung Baek,Kim Jong Ock,Shin Jong Woo,Lee Sung Ho,Park Joong Keun,Kim Taik Nam 한국재료학회 2004 한국재료학회지 Vol.14 No.4
A bio-composites were prepared by mechanical mixing with bioactive sol-gel derived $CaO-SiO_2$ and organic PEEK for bone repairing hybrid materials. The composites were characterized by in-vitro test. A bonelike apatite was formed on the surface of all bio-composites in SBF test. The cell morphology and adhesion on the surface of the composites having below 30% PEEK were clearly observed in L929 cell experiment.