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韓國 自生 범부채(Belamcanda chinensis (L.) DC.)의 種子發芽에 關한 硏究
朴潤点,劉成吾,崔權雄,鄭然玉 한국화훼연구회 1995 화훼연구 Vol.4 No.1
These studies were carried out to investigate the seed germination of Belamcanda chinensis (L.) DC. The results obtained are as follows : 1.Optimum temperature of seed germination was 25℃, and the seed germination rate was raised to 92% by 20/30℃ alternative temperature treatment. 2.Under the condition of moist low temperature storage, the germination rate was 53% at 42 days after sowing, but showed the germination rate of 11% at same period with dry low temperature storage. 3.The germination rate was higher in the light condition than in the dark condition. 4.The germination rate was higher when the seed coat was removed than when the seed coat was not removed or the seed coat was stratificated. 5.The germination rate was 80% with 100ppm GA3 treatment, and 76% wihh soaking treatment of 1% KOH solution for 24 hours.
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( Jee Woong Choi ),( Bo Ri Kim ),( Eunmi Seo ),( Sang Woong Youn ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.1
Background: The prevalence and clinical characteristics of psoriatic arthritis (PsA) in patients with psoriasis are not well described in Asian populations, including Koreans. Objective: The purpose of this study was to investigate the prevalence of PsA by using the classification of psoriatic arthritis (CASPAR) criteria on the basis of physical examination only, as well as its correlation with psoriasis severity and other medical conditions including nail psoriasis. Methods: A single- center, cross-sectional observational cohort study was conducted, and the included patients were evaluated for PsA according to the CASPAR criteria. The psoriasis area severity index (PASI) and the nail psoriasis severity index (NAPSI) were calculated. Results: The prevalence of PsA in patients with psoriasis in Korea was 13.5%. When performing logistic regression, hyperlipidemia and localized pustular psoriasis were found to be significant predictors of PsA. The PASI score was significantly higher in PsA patients than in those with psoriasis alone (p=0.014). Psoriatic nail involvement was found in 85.5% of the study population, and all PsA patients had nail psoriasis. The mean NAPSI score was higher in patients with PsA; however, the difference was not statistically significant. Conclusion: There was a close relation between psoriasis severity and PsA, although nail psoriasis severity was not related to PsA status. Dermatologists can diagnose PsA from current physical findings by using the CASPAR criteria. To validate the CASPAR criteria for PsA diagnosis, the definition of nail psoriasis clinical types and severity in the CASPAR criteria should be reviewed again. (Ann Dermatol 29(1) 48∼54, 2017)
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( Sang Woong Youn ),( Bo Ri Kim ),( Joo Heung Lee ),( Hae Jun Song ),( Yong Beom Choe ),( Ji Ho Choi ),( Nack In Kim ),( Kwang Joong Kim ),( Jai Il Youn ) 대한피부과학회 2015 Annals of Dermatology Vol.27 No.2
Background: The development of therapies for psoriasis has led to the need for a new strategy to the treatment of patients with moderate-to-severe psoriasis. New consensus guidelines for psoriasis treatment have been developed in some countries, some of which have introduced treatment goals to determine the timing of therapeutic regimens for psoriasis. Objective: To investigate the opinions held by Korean dermatologists who specialize in psoriasis about treatment goals, and to compare these with the European consensus. Methods: Korean dermatologists who specialize in psoriasis were asked 11 questions about defining the treatment goals for psoriasis. The questionnaire included questions about the factors used to classify the severity of psoriasis, defining the induction and maintenance phases of psoriasis treatment, defining treatment responses during the induction phase, and defining treatment responses during the maintenance phase. Results: The Korean consensus showed responses that were almost similar to the European consensus, even without using the Delphi technique, which uses repeated rounds of questions to reach a consensus. Only one response that related to psoriasis severity in the context of the quality of patients` lives differed from the European consensus. Conclusion: The concept of using treatment goals in the treatment of moderate-to-severe psoriasis can be applied to Korean psoriasis patients. Since a tool for assessing the quality of patients` lives is not commonly used in Korea, the development of a simple, rapidly completed, and region-specific health-related quality of life assessment tool would enable treatment goals to be used in routine clinical practice.(Ann Dermatol 27(2) 184∼189, 2015)
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Adherence to Topical Therapies for the Treatment of Psoriasis: Surveys of Physicians and Patients
( Jee Woong Choi ),( Bo Ri Kim ),( Sang Woong Youn ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.5
Background: There have been few studies of treatment adherence in Asian patients with psoriasis and understanding of the factors is important to improve outcomes. Objective: To provide an overview of treatment adherence among Korean patients with psoriasis and to understand how the perceptions of patients and physicians affect topical treatment adherence. Methods: A cross-sectional questionnaire survey was conducted to determine the views and opinions of dermatologists and psoriasis patients on topical treatment adherence. The survey items were developed in collaboration with psoriasis experts. Results: Twenty-six dermatologists and fifty patients completed their questionnaire. In the physician survey, more than half of dermatologists only inquired about adherence up to 20% of the time. Most dermatologists generally thought that their patients had high expectations of treatment. Nearly 40% of dermatologists reported that more than 60% of their patients adhered to the prescribed topical treatment. In the patient survey, more than 15% of patients reported that they did not receive enough information about the drug. Around one-fifth of the patients also complained about the physical properties of the products. The majority of patients were confident with the current topical treatments and expected fast improvement, within a couple of weeks. The most common reason for low adherence was forgetfulness. Inconvenience and concerns about side effects were common reasons for topical treatment discontinuation. Conclusion: Because adherence to topical treatment is a complex, multifactorial issue with factors varying between patients, dermatologists should focus on determining each patient`s individual adherence barriers to achieve good treatment outcomes. (Ann Dermatol 29(5) 559∼564, 2017)
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( Sang Woong Youn ),( Bo Ri Kim ),( Joo Heung Lee ),( Hae Jun Song ),( Yong Beom Choe ),( Ji Ho Choi ),( Nack In Kim ),( Kwang Joong Kim ),( Jai Il Youn ) 대한피부과학회 2015 Annals of Dermatology Vol.27 No.3
Background: The development of therapies for psoriasis has led to the need for a new strategy to the treatment of patients with moderate-to-severe psoriasis. New consensus guidelines for psoriasis treatment have been developed in some countries, some of which have introduced treatment goals to determine the timing of therapeutic regimens for psoriasis. Objective: To investigate the opinions held by Korean dermatologists who specialize in psoriasis about treatment goals, and to compare these with the European consensus. Methods: Korean dermatologists who specialize in psoriasis were asked 11 questions about defining the treatment goals for psoriasis. The questionnaire included questions about the factors used to classify the severity of psoriasis, defining the induction and maintenance phases of psoriasis treatment, defining treatment responses during the induction phase, and defining treatment responses during the maintenance phase. Results: The Korean consensus showed responses that were almost similar to the European consensus, even without using the Delphi technique, which uses repeated rounds of questions to reach a consensus. Only one response that related to psoriasis severity in the context of the quality of patients` lives differed from the European consensus. Conclusion: The concept of using treatment goals in the treatment of moderate-to-severe psoriasis can be applied to Korean psoriasis patients. Since a tool for assessing the quality of patients` lives is not commonly used in Korea, the development of a simple, rapidly completed, and region-specific health-related quality of life assessment tool would enable treatment goals to be used in routine clinical practice. (Ann Dermatol 27(2) 184∼189, 2015)
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( Sung Hwan Youn ),( Chong Won Choi ),( Jae Woo Choi ),( Bo Ri Kim ),( Sang Young Byun ),( Sang Woong Youn ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: We usually divided cosmetic facial zone into the T zone and U zone by the level of sebum secretion. Our recent studies suggested that the perioral area showed different characteristics in the aspect of acne development. Objectives: To investigate the unique characteristics of the O zone (perioral area) among the three facial areas. Methods: A total of 102 patients clinically diagnosed as acne vulgaris were included. The acne lesions were counted from the clinical digital photographs by facial areas. The sebum level was measured using Sebumeter®. Area-weighted (AW) sebum and AW density of three areas of face were calculated. Statistical analysis was performed according to age and gender. Results: There were no differences in the mean AW sebum level between the gender and age groups. Male has higher AW density of acne lesions than female at the O zone. The mean AW density of acne lesions on the NT zone, U zone, and whole face showed decrease by age, but at the O zone, 21-30 years group showed the highest mean AW density of acne. Conclusion: We suggested that the O zone is an independent facial zone, which showed a moderate-to-high sebum secreting area, maintained the acne lesions development by age, and predominated acne lesions in the male acne patients than female acne patients. Therefore, the O zone should be separated from the usual cosmetic T zone, and NT zone should replace the old T zone.
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Long-term outcomes of abdominal paraganglioma
Hye Ryeon Choi,Zeng Yap,Soon Min Choi,Sun Hyung Choi,Jin Kyong Kim,Cho Rok Lee,Jandee Lee,Jong Ju Jeong,Kee-Hyun Nam,Woong Youn Chung,Sang-Wook Kang 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.99 No.6
Purpose: Paragangliomas (PGL) are rare neuroendocrine tumors derived from chromaffin cells of the autonomic nervous system. We aim to describe our experience and the long-term outcome of abdominal PGL over the last decade. Methods: A retrospective review of patients diagnosed with PGL in our hospital between November 2005 and June 2017 was conducted. All nonabdominal PGL were excluded and the clinicopathological features and long-term outcomes of the patients were analyzed. Results: A total of 46 patients were diagnosed with abdominal PGL. The average age of diagnosis was 55.4 years and there was no sex predilection. The average tumor size was 5.85 cm and they were predominantly located in the infrarenal position (50%). The mean follow-up period was 42 months (range, 1.8–252 months). All patients with metastases had Pheochromocytoma of the Adrenal Gland Scaled Score (PASS) of ≥4. One patient presented with synchronous metastases while 2 developed local recurrence and distant metastases. One presented with only local recurrence. One patient died 5 years after diagnosis. Conclusion: Abdominal PGL is a rare tumor with excellent long-term prognosis. Recurrence although uncommon, can occur decades after initial diagnosis. Long-term follow-up is therefore recommended for all patients with PGL, especially in patients with PASS of ≥4
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