원형 탈모증 환자의 혈청 철분 조사

이종석,정현,이성열 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

Alopecia areata is characterized by rapid and complete loss of hair in one, or more often several, round or oval patches, usually on the scalp. It is not at present possible to attriute all or indeed any case of alopecia areata to a single cause. Among the many factors which appear to be implicated in at least a proportion of cases are the patient's genetic constitution, the atopic state, non-specific immune and organ-specific autoimmune reactions and possibly emotional stress. Iron deficiency as an etiological factor in diffuse alopecia and androgen-dependent alopecia has been discussed previously. We decided to investigate the iron status of alopecia areata patients visiting our department for treatment. All these patients had alopecia areata for at least 6 months before visiting our department. Thirty patients(16 female and 14 male) participated in the study. Blood samples were sent for full blood count, including estimation of mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, Fe, TIBC, and serum ferritin. The results are shown in Table. We suggest that serum ferritin assay should be included in the hematological assessment of patients with alopecia areata.

췌장내 총담관 초음파 신주사법과 인도자로서의 콧수염 싸인

이성우,은충기,한창열,정덕환 인제대학교 1990 仁濟醫學 Vol.11 No.2

저자들은 전향적으로 총 113명의 늑골하 사위주사(subcostal oblique U.S. scan)를 하였고, 췌장내 총담관을 전 예에서 볼 수 있었다. 저자들은, 첫째 간외담관의 전통적인 초음파 주사와 저자들의 '새 방법이 조합되면 간외담관 전장이 깨끗이 보여지며, 이렇게 하기 위한 지표로 십이지하 총담관과 근위고유간동맥-원위총간동맥으로 구성되는 "moustache sign"(콧수염 싸인)의 새로운 싸인을 소개하고, 둘째 원위총담관과 췌장 두부에 생긴 질환을 찾아내고 그 감별점을 소개해 진단적 정확성을 향상시키는 초음파 방법을 제시한다. The authors did the subcostal scans of total 113 patients propspectively and all the pancreas CBD was visualized. The authors would present : 1. to introduce a new landmark "moustache sign", which was composed of infraduodenal common bile duct, and the distal common hepatic and proximal hepatic arteries to visualize the whole common duct, when combined with the conventional ultrasound scans of common duct 2. to present a scanning method to improve the diagnostic accuracy for detecting a disease at the distal CBD and pancreas head, and their differential points.

인체 두피 모낭 외측모근초 각질형성 세포의 배양

이종석,이성열,박영립,서용원,황규왕 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

Follicular stem cell was assumed as a hair matrix cell. But, recently it was suggested that follicular stem cells were in the bulge portion of outer root sheath of hair follicles, and its proofs were reported. We tried to culture outer root sheath keratinocytes in the bulge portion of human hair follicles, and it would be experimental base for many factors and drugs realated with hair growth and differentiation. The outer root sheath keratinocytes were isolated from plucked human hair follicles, and could be serially passaged for up to 2 times on used biologic feeder cell layer.

악성 흑색종과 양성 멜라닌 세포성 모반에서 P53단백발현에 관한 면역조직화학적 연구

이성열,이종석,김대중 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1

This study was carried out to evaluate the aberrant expression of ?? protein using immunohistochemical method in 10 malignant melanoma and 10 melanocytic nevi. Eight out of 10(80%) and two out of 10(20%) showed positive reaction in the nucleus of malignant melanoma and benign melanocytic nevi, respectively. In conclusion, the demonstration of ?? protein in benign melanocytic nevi greatly hinders the possibility of a diagnostic use of ?? immunostaining in differentiating malignant melanoma from benign melanocytic nevi.

프로 축구선수의 손상 분석

이경태,송백용,양기원,김나민,김장렬,박성률 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Purpose : We evaluated and analyze the injury of the professional soccer player which would be helpful data for prevention of injury. Materials and Methods : Thirty-four professional soccer players were followed prospectively for one year and obtained injury exposure rate. We divided the injuries according to the position of the players incurred average 10 injuries for one year and the injury exposure rate was 2.9/1000hours, mostly strains and sprains of the lowre extremities. According to the player's position, the injured area and injury mechanism were different, Defence-Fielder and Mid-Fielder were more vulnerable to injury, 43% and 41.8% respectively, and mainly thigh and ankle injury. But Forward injury was less frequent and mainly leg and knee injury. In Goal-Keeper, neck and upper extremity injury was pre-dominant. Acute traumatic injury was 93% and recovery time was average on day, however, chronic overuse injury was less frequent but much longer time was required for recovery. Conclusion : The overuse injury is preventable by improving the environment and training program so that more attention is required.

竝流흐름 氣泡塔內에서 가스 홀드업에 관한 硏究 : Specially on aqueous of inorganic salts 無機鹽 水溶液을 中心으로

李相錄,金相烈 東亞大學校 大學院 1983 大學院論文集 Vol.7 No.-

Gas hold-up was studies according to the changes of Gas and liquid velocity, physical properties, geometrical type of distributor, and temperature for aqueous solution of inorganic salts in a cocurrent flow bubble column. The results were as follows: 1. σf decreases according to the concentration increases. especially this phenomenon was remarkably appeared in aqueous solution of potassium nitrate. 2. The effect of temperature on the gas hold-up was not found when the gas velocity is less than 3.65 cm/sec, but gas hold-up with temperature increase of solution rises up beyond gas velocity of 3.65 cm/sec. 3. The effect of solution velocity to the gas hold-up was not found when the solution velocity is less than 1.76 cm/sec, but gas hold-up with solution velocity increase lay down beyond solution velocity of 1.76 cm/sec. 4. The nondimensional equation by experimental data was represented in equation(7),(8).

相對的動的 筋持久力이 垂直跳 및 最大酸素攝取量에 미치는 影響

李喆熙,金承烈 啓明大學校 生活科學硏究所 1986 科學論集 Vol.12 No.-

After the authors tried to find the effect of Vertical jump and VO₂max in relative dynamic muscular endurance in eight male graduate students of D. University, the main results obtained were as follows; 1. The correlation coefficient between vertical jump and relative dynamic muscular endurance was revealed as a significantly high correlation at the level of 5 percent, r=0.75(p<0,05), ?=1.044X+5.2541, Sy.χ=4.27. 2. The correlation coefficient between VO₂ max and relative dynamic muscular endurance in the Upper Arm was revealed as a negative certainly correlation, r=-0.65, ?=-8.043X+81.90, Sy.χ=4.90, while the Leg turned out a certainly correlation, r=0.44, ?=10.94X+22.04, Sy.χ=11.49.

(Fe-5.8at.%Si)과 [Si 웨이퍼 또는(Fe-Si)합금]과의 접합에 의한 규소침투처리

이성열,정건영 한국해양대학교 산업기술연구소 2003 연구논문집 Vol.20 No.-

(Fe-5.8at.%Si)모재와 (Si 웨이퍼, FeSi_2, 또는 FeSi 합금)으로 구성된 확산쌍을 1423K에서 반응확산 열처리하였으며, 각각의 확산쌍에는 Fe_3Si상의 반응확산층이 형성되고 있다. Fe_3Si층의 두께는 반응확산 열처리시간의 제곱근에 비례하여 증가하는 것으로 나타났으며, Fe_3Si층 성장의 속도상수는 Si 원자 공급원의 종류에 따라 달라진다. 더욱이, 본 연구에서는 Fe_3Si층의 성장계수와 상호확산계수사이에는 이론적인 관계식이 성립함을 도출하였으며, 이 관계식으로부터 Fe_3Si층에 대한 상호확산계수를 결정하였다. Fe_3Si층 중에는 Kirkendall 기공이 형성되며, 기공의 발생정도는 Si 원자 공급원의 종류에 영향을 받지 않는 것으로 나타났다. 한편, (Fe-5.8at.%Si)dhk Fe_3Si 합금으로 구성되는 학산쌍의 열처리한 경우에는 고용체 α상이 형성되며, Kirkendall 기공발생도 Fe_3Si 층에 비하여 무시할 정도로 작게 나타났다. Reactive diffusion couples between (Fe-5.8at.%Si) and (Si wafer, FeSI_2, or FeSi alloy) has been heat-treated at 1423K. The layer of Fe_3Si phase has been only formed in each diffusion couple. The width of Fe_3Si layer is proportional to square root of diffusion time in each kind of diffusion couple. Growth rate of Fe_3Si layer is relied on the concentration of Si in the source of Si atoms. Interdiffusion coefficient of Fe_3Si has been determined from the derived relation between growth rate constant and interdiffusion coefficient in this work. It has been shown that the behavior of Kirkendall's void in Fe_3Si layer is not affected by the kind of Si source. But solid solution a has been formed in the diffusion couple between (Fe-5.8at.%Si) and Fe_3Si alloy. Kirkendall's void formed in diffusional a is neglectively smaller than the case of Fe_3Si phase.

개량된 초임계수 산화법에 의한 염소계 유기물 (PCB, 4-DCBz)의 완전분해반응

이상환,박기철,박윤열,양종규,김정성,富安博 한국환경과학회 2005 한국환경과학회지 Vol.14 No.5

For the destruction of toxic chlorinated organic compounds, this study proposes improved supercritical water oxidation method (multistep oxidation) using sodium nitrate as an oxidizer. This method solves the problems involved in the existing supercritical water oxidation method. Multistep oxidation means that NaNO₃ is oxidized to N₂ via NaNO₂ and NO. Toxic and hard to destroy organic substances like para-dichlorobenzen(4-DCBz), polychlorinate biphenyl(PCB) ware oxidized to non toxic substances in a condition, in which rapid pressure and temperature rise is restrained as much as possible. 4-dichlorobenzene(4-DCBz) and Polychlorinate biphenyl(PCB) in condition(450℃, p_(w)=0.25g/cm³, 30min) Was discomposed perfectly.

만성 정신분열증 음성증상에 대한 Mianserin 효과

이정태,서상원,유태열,박원명,김광수,전양환 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.2

This study was designed to examine the mianserin effects on the negative symptoms of chronic schizophrenia. The chronic schizophrenics(N=14) diagnosed by DSM-Ⅲ-R, who were treated at the Catholic University St. Mary Hospital from March 1, 1993 to August 31, 1995, were divided into two groups. One group was composed of 7 patients who were treated with a single classical antipsychotic agent(monotherapy group, MG), and another was composed of 7 patients treated with combined medications(combined therapy group, CG), including classical antipsychotics plus fixed dose of mianserin 30 ㎎/day at bed time. Symptoms were evaluated by BPRS(Brief Psychiatric Rating Scale) and PANSS(Positive and Negatve Syndome Scale) biweekly for 6 weeks, i.e., total 4 times(at baseline, at 2 weeks, at 4 weeks, and at 6 weeks). The results were as follows : 1) Assessed by PANSS, the negative symptoms of CG were statistically significantly improved more than those of MG at 2 weeks, at 4 weeks, and at 6 weeks. 2) Assessed by PANSS, the positive symptoms of CG were not statistically different from those of MG. In both of CG and MG, there was no difference of the positive symptoms across time intervals. 3) Assessed by PANSS, the total symptoms of CG were statistically significantly improved more than those of MG at 2 weeks, at 4 weeks, and at 6 weeks. But, assessed by BPRS, the total symptoms of CG were not statistically different from those of MG. 4) Assessed by PANSS, the general psychopathology symptoms of CG were not statistically different from those of MG. In CG, the general psychopathology stmptoms at 6 weeks were statistically significantly improved more than those of baseline. In summary, mianserin, when combined with classical antipsychotic agent, appears to be effective in diminishing negative symptoms of chronic schizophrenic patients. However, it did not influence positive symptoms.