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부산 서독적십자병원 폐원과정을 통해 본 1950년대 한독관계
이정민 ( Lee¸ Jeongmin ) 수선사학회 2021 사림 Vol.- No.77
This study examined the process of closing the DRK(West German Red Cross) hospital in Busan with an emphasis on the illegal disposal of foreign currency in 1956 and the discussions about hospital closure from 1958 to 1959. DRK hospital was founded by mutual agreement with the West German government and the US government in support of the postwar restoration of South Korea, and the strategic interests of West Germany and the US were inevitably reflected in the closing process. When medical aid from the Swedish Red Cross Hospital and other countries ended, the United States' strategic needs for the West German Red Cross Hospital also declined. West Germany felt difficult to maintain a hospital with the growing financial burden of free medical treatment. The hospital had internal accidents continuously. The Rhee Syngman government was unable to express its position during the opening and closing of the DRK Hospital, but it played some role in the worsening financial situation and the closing of the hospital, because they made no effort to improve the situation.
Jeongmin Lee,Sangwook Lee,Wooram Jung,Guk Bae Kim,Taehun Kim,Jiwon Seong,장혜민,Young Noh,Na Kyung Lee,Boo Rak Lee,Jung-Il Lee,Soo Jin Choi,Wonil Oh,Namkug Kim,Seunghoon Lee,Duk L. Na 대한의학회 2022 Journal of Korean medical science Vol.37 No.31
Background: To deliver therapeutics into the brain, it is imperative to overcome the issue of the blood-brain-barrier (BBB). One of the ways to circumvent the BBB is to administer therapeutics directly into the brain parenchyma. To enhance the treatment efficacy for chronic neurodegenerative disorders, repeated administration to the target location is required. However, this increases the number of operations that must be performed. In this study, we developed the IntraBrain Injector (IBI), a new implantable device to repeatedly deliver therapeutics into the brain parenchyma. Methods: We designed and fabricated IBI with medical grade materials, and evaluated the efficacy and safety of IBI in 9 beagles. The trajectory of IBI to the hippocampus was simulated prior to surgery and the device was implanted using 3D-printed adaptor and surgical guides. Ferumoxytol-labeled mesenchymal stem cells (MSCs) were injected into the hippocampus via IBI, and magnetic resonance images were taken before and after the administration to analyze the accuracy of repeated injection. Results: We compared the planned vs. insertion trajectory of IBI to the hippocampus. With a similarity of 0.990 ± 0.001 (mean ± standard deviation), precise targeting of IBI was confirmed by comparing planned vs. insertion trajectories of IBI. Multiple administrations of ferumoxytol-labeled MSCs into the hippocampus using IBI were both feasible and successful (success rate of 76.7%). Safety of initial IBI implantation, repeated administration of therapeutics, and long-term implantation have all been evaluated in this study. Conclusion: Precise and repeated delivery of therapeutics into the brain parenchyma can be done without performing additional surgeries via IBI implantation.
Lee, Jaegi,Lee, Yongwon,Lee, Jeongmin,Lee, Sang-Min,Choi, Jeong-Hee,Kim, Hyungsub,Kwon, Mi-Sook,Kang, Kisuk,Lee, Kyu Tae,Choi, Nam-Soon American Chemical Society 2017 ACS APPLIED MATERIALS & INTERFACES Vol.9 No.4
<P>We present an ultraconcentrated electrolyte composed of 5 M sodium bis(fluorosulfonyl)imide in 1,2-dimethoxyethane for Na metal anodes coupled with high-voltage cathodes. Using this electrolyte, a very high Coulombic efficiency of 99.3% at the 120th cycle for Na plating/stripping is obtained in Na/stainless steel (SS) cells with highly reduced corrosivity toward Na metal and high oxidation durability (over 4.9 V versus Na/Na+) without corrosion of the aluminum cathode current collector. Importantly, the use of this ultraconcentrated electrolyte results in substantially improved rate capability in Na/SS cells and excellent cycling performance in Na/Na symmetric cells without the increase of polarization. Moreover, this ultraconcentrated electrolyte exhibits good compatibility with high-voltage Na4Fe3(PO4)(2)(P2O7) and Na-0.7(Fe0.5Mn0.5)O-2 cathodes charged to high voltages (>4.2 V versus Na/Na+), resulting in outstanding cycling stability (high reversible capacity of 109 mAh g(-1) over 300 cycles for the Na/Na4Fe3(PO4)(2)(P2O7) cell) compared with the conventional dilute electrolyte, 1 M NaPF6 in ethylene carbonate/propylene carbonate (5/5, v/v).</P>
Lee, Yongwon,Lee, Tae Kyung,Kim, Saehun,Lee, Jeongmin,Ahn, Youngjun,Kim, Koeun,Ma, Hyeonsu,Park, Gumjae,Lee, Sang-Min,Kwak, Sang Kyu,Choi, Nam-Soon Elsevier 2020 Nano energy Vol.67 No.-
<P><B>Abstract</B></P> <P>Li metal anodes and Ni-rich layered oxide cathodes with high reversible capacities are promising candidates for the fabrication of high energy density batteries. However, low Coulombic efficiency, safety hazards from likely vertical Li growth, and morphological instability of Ni-rich cathodes hinder the practical applications of these electrodes. Here, we report that fluorinated compounds can be employed as interface modifiers to extend the applicable voltage range of ether-based electrolytes, which have been used specifically so far for lithium metal batteries with charging cut-off voltages lower than 4 V (vs. Li/Li<SUP>+</SUP>). A complementary electrolyte design using both 1,1,2,2-tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether and fluoroethylene carbonate in concentrated ether-based electrolytes significantly improves the capacity retention (99.1%) in a Li|LiNi<SUB>0.8</SUB>Co<SUB>0.1</SUB>Mn<SUB>0.1</SUB>O<SUB>2</SUB> full cell, with a high Coulombic efficiency of 99.98% after 100 cycles at 25 °C. Thus, the modified electrolyte system is promising for addressing the reductive and oxidative decompositions of labile ether-based electrolytes in high energy density Li metal batteries with Ni-rich cathodes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ether-based electrolyte formulation for 4V-class Li metal batteries is presented. </LI> <LI> FEC and TTE are employed as the electrode–electrolyte interface modifiers. </LI> <LI> Fluorine-enriched interfaces enable high-performance Li metal batteries. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Lee, Jeongmin,Lee, Yeon Soo,Ahn, Kook-Jin,Lee, Song,Jang, Jinhee,Choi, Hyun Seok,Jung, So-Lyung,Kim, Bum-soo,Jeun, Sinsoo,Hong, Yongkil Korean Society of Magnetic Resonance in Medicine 2016 Investigative Magnetic Resonance Imaging Vol.20 No.3
Purpose: To understand clinical significance of irregular interface between meningioma and adjacent brain parenchyma in predicting histological grading of tumor, focusing on brain parenchymal invasion. Materials and Methods: Pathologically confirmed 79 cases with meningiomas with pathological reports about the presence of parenchymal invasion were included. We defined the presence of interface irregularity as either spiculations or fuzzy margins between the tumor and brain parenchyma. We counted number of spiculations and measured ratio of fuzzy margin length to whole length of mass with consensus of two neuroradiologists. We classified the patients into Present group and Absent group, and the two groups were compared by using the Mann-Whitney U test. Statistical correlations between the presence of an interface irregularity and brain parenchymal invasion by the tumor as well as meningioma histological grade were tested with chi-square test. The optimal cutoff values of spiculation numbers and the ratio of fuzzy margins were determined. The sensitivity and specificity of number of spiculations, ratio of fuzzy margin and the presence of irregular interface as combined parameters for predicting the parenchymal invasion were calculated using ROC curve analysis. Results: Statistically significant differences were noted between the Present and Absent groups for number of spiculations and ratio of fuzzy margin (P = 0.038 and P = 0.028, respectively). The optimal cutoff value for number of spiculations (> 4.5 with 61.1% sensitivity and 68.9% specificity) and the ratio of fuzzy margin (> 0.24 with 66.7% sensitivity and 65.6% specificity) were determined. The sensitivity and specificity of interface irregularity as the combined parameters were 72% and 59%, respectively. The interface irregularity between tumor and brain parenchyma significantly correlated with not only brain parenchymal invasion (P = 0.001) and but also histological grade (P < 0.001). Conclusion: The interface irregularity between tumor and brain parenchyma in MRI can be a strong predictive factor for brain parenchymal invasion and high grade meningioma.
Lee, Yongwon,Lee, Jaegi,Lee, Jeongmin,Kim, Koeun,Cha, Aming,Kang, Sujin,Wi, Taeung,Kang, Seok Ju,Lee, Hyun-Wook,Choi, Nam-Soon American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.17
<P>Sodium (Na) metal anodes with stable electrochemical cycling have attracted widespread attention because of their highest specific capacity and lowest potential among anode materials for Na batteries. The main challenges associated with Na metal anodes are dendritic formation and the low density of deposited Na during electrochemical plating. Here, we demonstrate a fluoroethylene carbonate (FEC)-based electrolyte with 1 M sodium bis(fluorosulfonyl)imide (NaFSI) salt for the stable and dense deposition of the Na metal during electrochemical cycling. The novel electrolyte combination developed here circumvents the dendritic Na deposition that is one of the primary concerns for battery safety and constructs the uniform ionic interlayer achieving highly reversible Na plating/stripping reactions. The FEC-NaFSI constructs the mechanically strong and ion-permeable interlayer containing NaF and ionic compounds such as Na<SUB>2</SUB>CO<SUB>3</SUB> and sodium alkylcarbonates.</P> [FIG OMISSION]</BR>
Lee, Jeongmin,Lee, Hyung Ju,Ryu, Jaiyoung,Lee, Seong Hyuk Elsevier 2018 INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER - Vol.117 No.-
<P><B>Abstract</B></P> <P>The present study numerically investigated the three-dimensional turbulent flow and heat transfer characteristics of longitudinal vortices embedded in a turbulent boundary layer in a bent channel and examined the effects of a spanwise pressure gradient on the distortion of the turbulent boundary layer. The commercial code (ANSYS Fluent v17.0) was used for the simulation with the Reynolds stress model (RSM) to consider anisotropic effects. The simulation results showed that an asymmetric distortion of the turbulent boundary layers and a substantial change in the vortex shape were caused by the presence of an additional mean shear rate, originated from the spanwise pressure gradient. It was also found that an increase in the spanwise pressure gradient contributed to an enhancement of production of turbulent kinetic energy, resulting in stronger mixing flows. In particular, the Stanton number had an asymmetric distribution mainly in the bent region where the spanwise pressure gradient was dominant.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The effect of spanwise pressure gradient on flow and heat transfer characteristics is examined. </LI> <LI> The simulation shows an asymmetric distortion of the turbulent boundary layers. </LI> <LI> The Stanton number increases because of the spanwise pressure gradient. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Lee, Hwijong,Kim, Gwansik,Lee, Byunghun,Kim, Jeongmin,Choi, Soon-Mok,Lee, Kyu Hyoung,Lee, Wooyoung Elsevier 2017 Scripta materialia Vol.135 No.-
<P><B>Abstract</B></P> <P>Polycrystalline bulks of Si-content tuned Ge-doped higher manganese silicides (HMSs) were fabricated to elucidate the effects of Si content on the phase formation behavior and thermoelectric properties. The phase formation and electronic transport characteristics of HMSs were significantly dependent on Si content. Improved power factor was obtained at higher Si contents because of an enhanced Seebeck coefficient due to the increase in density of states effective mass, maintaining electrical conductivity. Furthermore, the lattice thermal conductivity was reduced through Si-content tuning, which suppressed the formation of secondary phases. Thus, a maximum <I>ZT</I> of 0.61 at 823K was obtained in MnSi<SUB>1.77</SUB>Ge<SUB>0.027</SUB>.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>