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      • KCI등재

        푸른길 공원의 대기 환경 특성에 관한 연구

        민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3

        Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.

      • SCIESCOPUSKCI등재

        Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis

        Park, Hyun-Gyu,Do, Jin-Hwan,Chang, Ho-Nam The Korean Society for Biotechnology and Bioengine 2003 Biotechnology and Bioprocess Engineering Vol.8 No.1

        With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.

      • 국소성 분절성 사구체 경화증의 완전 관해 후 발병한 IgA 신병증 1예

        임현민,김현정,박민석,주혜원,최원,김상현,박원도 인제대학교 2006 仁濟醫學 Vol.27 No.-

        We report a rare case of primary glomerular disease with IgA nephropathy in a 43-year old man. 7-years ago, he was diagnosed with minimal change nephrotic syndrome. After treatment with steroid for 1-year, azotemia and proteinuria were improved. But, nephrotic range proteinuria was relapsed within 1 week after cessation of steroid. Renal biopsy revealed focal segmental glomerulosclerosis, and achived a complete remission with the use of steroids and cyclophosphamide. Then, he was followed up with normal renal function for 4-years. On admission, the patient showed generalized edema and marked proteinuria. In 3rd renal biopsy, mesangial proliferative glomerulonephritis with diffuse global sclerosis was observed. Electron microscopy showed electron-dense deposit on the mesangium with slight mesangial proliferation, and immunofluoroscence microscopy showed granular deposits of IgA and IgM. These features were consistent with IgA nephropathy, different from results of previous biopsies. The pathogenesis of IgA nephropathy occurred with primary FSGS is not clear, as well as treatment. Now, proteinuria is improving, steroid and cyclophosphamide are probably useful for the disease.

      • SCOPUSSCIEKCI등재
      • KCI등재

        저칼슘식이 생쥐 하악골에서 파골세포의 Tartrate저항성 산성인산분해효소 활성에 대한 세포화학적 연구

        박은주,임도선,김현만,고재승 대한구강해부학회 1994 대한구강해부학회지 Vol.18 No.1

        The present study was carried out to exanine the morphological changes and TRACP (Tartrate resistant acid phosphatase) activity in the resorption of mandibular bones of mouses resulted, established by low calcium diet. Mice were divided into two groups; one was the calcein group for fluorescent microscopy, the other was the non-calcein group for light and electron microscopy. After calcein injection, mice(ICR) were fed either a low calcium diet (0.01% Ca, 0.75% P) or control diet (0.1% Ca. 0.75% P). Non-calcein group were also fed a low calcium diet or control diet. Mice were sacrificed on 3, 7 and 14 days. For fluorescent microscopy study, fixed undecalcified alveolar bones were embedded in Epon 812, and ground sectioned to study the new bone formation after calcein injection. For the TRACP histochemical study, fixed decalcified alveolar bones were incubated in p-NPP (p-nitrophenyl phosphate) media. For the transmission electron microscopic study, incubated alveolar bone were post fixed in OsO_(4), embedded with Epon 812 for the study of TRACP localzation and activity. The observed results were as follows. 1. Low calcium diet induced bone resorption in buccal and lingual sides of alveolar bone, while the lingual side of alveolar bone was not resorbed in the control group. Bone resorption increased over the period of low calcium diet. 2. The alveolar bone proper of the lingual alveolar bone continued to deposit new bone of the periodontal side even after the low calcium diet. 3. After low calcium diet TRACP activity increased in the cytoplasm of osteoclast, extracellular ruffled border. TRACP activity was also found at the eroded bone matrix after bone resorption, and in the cytoplasm of detached osteoclast. In the immature osteoclast enzyme activity was confined in rER. No enzyme activity was found in the osteoblast.

      • 불량행위 청소년을 중심으로 한 학교폭력 가해자의 사회인구학적 특성 및 정신병리(V)

        박지도,최현경,장우성,조동환,김정기 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

        연구목적 : 이 연구는 불량행위 청소년군과 학생군을 대상으로 학교내외에서 행하는 폭력행동의 특징을 알아보고 특히 가해자의 정신병리와 청소년의 폭력행동과의 관계를 알아봄으로써 학교폭력의 이해와 대처방법 그리고 예방프로그램의 수립에 도움이 되고자 한다. 방 법 : 불량행위 청소년(청소년 선도프로그램인 BBS참석자) 남자 331명과 남자 중고등학교생 394명을 폭력의 유형을 괴롭힘, 금품갈취, 신체적 폭력, 언어적 폭력, 위협 등의 5가지 유형으로 나눈 설문문항을 바탕으로 각 경우의 경험빈도를 5점 척도로 하여 각 문항에서 3점 이상을 가해자군으로 분류하였으며 설문지를 통한 조사와 정신병리의 측정도구로서 한국판 아동-청소년 문제행동 평가 척도표(CBCL : Child Behavior Checklist, 청소년용)및 청소년의 자기개념을 알아보기 위해 한국판 피어스-해리스 소아 자기 개념척도(Piers-Harris Children's Self-Concept Scale, Piers, 1984, 이하 자기개념척도)를 적용하였으며 Chi-square test, T-test, 그리고 Two-way ANOVA를 사용하여 비교하였다. 결 과 : 사회 인구학적 특성에서는 대부분의 요인에서 불량행위군과 학생군 그리고 가해자군과 비가해군간에 차이는 보이지 않았으나 흡연과 음주하는 비율이 불량행위군과 학생군 두 군 모두 가해자군이 비가해자군보다 의미있게 높게 나타났다. 부모의 부부싸움 빈도는 불량행위군에서는 가해자와 비가해자군간에 차이를 보이지 않았으나 학생군에서는 가해자군에서 종종 싸운다는 비율이 의미있게 높게 나타났다. 학교생활에서는 성적이나 교우관계에서는 두 군 사이와 가해여부에 따라 유의한 차이를 보이지는 않았으며 성적은 불량행위군이 학생군에 비해 낮은 반면 가해여부에 따라서는 차이가 없었다. 하지만 학생군에서는 가해자군이 비가해자군보다 성적이 낮았으며 만화방을 이용하는 빈도도 가해자군에서 높게 나타났다. 폭력물 시청 시 느낌은 불량행위군과 학생군 모두에게서 가해자군이 비가해자군에 비해 흥분된다는 비율이 높게 나타났다. CBCL(Child Behavior Checklist)척도는 불량행위군의 경우 비행, 공격성, 외현화, 사회성 척도가 학생군에 비해 유의하게 높았고 위축, 사회적 미성숙, 사고문제, 주의집중, 내재화 척도는 학생군에서 불량행위군에 비해 유의하게 높았다. 전체 대상군을 가해자군과 비가해자군으로 나누어 비교하였을 때 신체증상, 사고문제, 주의집중, 비행, 공격성, 내재화, 외현화척도에서 가해자군이 비가해자군에 비해 유의하게 높았으며 군과 가해여부의 상호작용효과 검증결과에서는 유의한 상호작용을 보이는 척도는 없었으나 각 집단의 모든 척도에서 가해자군이 비가해자군보다 높은 점수를 보여주었으며 불량행위군의 경우 가해자군일수록 비행, 공격성, 외현화 척도가 높아지는 경향을 보였으며 학생군의 경우에서도 마찬가지로 비행, 공격성, 외현화 척도에서 가해자군이 비가해자군보다 높게 나타났다. 자기개념 척도는 불량행위군의 경우 행동, 지적학업척도에서 학생군에 비해 유의하게 낮게 나타났으며 불안, 인기척도는 학생군에서 불량행위군보다 유의하게 낮게 나타났다. 전체 대상군을 가해자군과 비가해자군으로 나누어 비교하였을 때 행동, 지적학업척도는 가해자군이 비가해자군에 비해 유의하게 낮은 점수를 보여주었으며 각 군과 가해여부의 상호작용검증결과에서는 유의한 상호작용효과를 보인 것은 없었으나 두 군 모두 행동척도가 가해자군이 비가해자군에 비해 낮은 경향을 보여주었다. 결 론 : 불량행위군과 학생군에서의 폭력가해자는 사회인구학적 변인에서는 비가해자와 유사한 특징을 가지나 각자의 내재된 심리상태와 정신병리에 따라 폭력 영상물과 음주 흡연의 가능성증가 그리고 가정에서의 폭력의 학습 등 주변의 위해 요인에 가해자군이 비가해자군에 비해 영향을 많이 받는 것으로 생각된다. 이에 학교폭력에 대한 대책수립 시 결과에만 초점을 맞춘 처벌 위주의 방식에서 벗어나 이들이 가진 심리적 특징과 정신병리를 이해하고 그에 따른 예방적인 대책수립이 필요할 것으로 생각된다. Objective : The purpose of this study was to identify the characteristics of school violence, self concept, psychopathology and psychosocial characteristics of male aldolescent delinquency doing school violence. And we hoped to use this result as basic material for prevention of school violence through comparison of those of students group. Method : We surveyed 725 male adolescents including 331 deliquents from educational program called "Big Brothers and Sister" in Pusan. We used self-reporting questionnaire composed of demographic data and attitude to violence. In order to investigate the psychopathology and self-concept, we used Child Behavior Check List, Youth edit, Korean version(CBCL) and the Piers-Harris Children's Self-Concept Scale. Statistical methods employed were Chi-square, t-test, two-way ANOVA. Result : The results show that in most demographic and psychosocial factor including age, education, socio-economic condition, religion and relationship with friends, there was no significant difference between delinquent and student group. And there was no significant difference between bully and non-bully in both group. The frequency of alcohol drinking and smoking were higher in bullying groups. For the feeling of watching violent mass-media, bullying delinquents reported more excited state than non-bullying delinquents in both group. On results of CBCL, subscales of delinquent behavior, aggressive behavior, externalizing problem, social scale in delinquent group were higher than those in student group. Subscale of somatic complaints, thought problem, attention problem, delinquent behavior, aggressive behavior, internalizing problem, and externalizing problem in bullying group were higher than those in nonbullying group. In both delinquent and student group, subscale of delinquent behavior, aggressive behavior, and externalizing problem in bullying group were significantly higher than those in nonbully group. In the results of self-concept scale, subscales of behavior, intellectual and school status in delinquent group were lower than those in student group. Subscale of somatic complaints, thought problem, attention problem, delinquent behavior, aggressive behavior, internalizing problem, and externalizing problem in bullying group were higher than those in nonbully group Conclusion : In both delinquent and student groups, most psychosocial factors in bully group were not significantly different with those in nonbully group. Bully group was more influenced by internal psychic state, psychopathology and environmental factor than nonbully group.

      • WHO 침구임상 지침서 개정을 위한 국제회의 보고

        박히준,서정철,김세현,김상우,안경애,임사비나,김용석,최도영,강성길 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

        The Working Group on the revision of Clinical Research Methodology for Acupuncture met in Seoul, Republic of Korea from 24 to 26 August 2005. The main objectives of the meeting were to review the regional publication guidelines for Clinical Research on Acupuncture, to make necessary revisions in the guidelines, to make recommendations on further collaboration and activities in the field of research on acupuncture, and to discuss scientific evidence-based approaches in the clinical research on acupuncture. Fourteen members from the eight Member States, one secretariat staff from the WHO Regional Office for the Western Pacific and ten observers from the Republic of Korea attended the meeting. The members presented their papers to review the current status of clinical research on acupuncture. The drafts of proposed revision to the previous guidelines for clinical research methodology on acupuncture were discussed extensively. The issues covered during the discussion included: the definition of the new terms; reorganization of clinical research design; revision and update of contents (e.g., control group); introduction of Institutional Review Board (IRB) on the section of ethical approval; additional outcomes including health-related quality of life (HRQOL), qualitative measures, etc. In the course of these discussions, the working group developed the revised guidelines for clinical research on acupuncture and made recommendations for promoting the dissemination of the revised guidelines.

      • 후매립 단일앵커의 강도특성

        박완신,황선경,윤현도 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

        Many models for the design of post-installed steel anchors are presented in this paper. These approach are compared to each other, especially the well-known provisions of CEB method, ACI 349-90 and the CCD method. The use of these methods to predict the concrete failure load of fastenings in uncracked concrete under monotonic loading for important applications is compared. Variables included single anchors away from and close to the edge, embedment depth, concrete strength, tension loading, and shear loading. A data bank including Korean, European and American tests was evaluated. The comparison shows the CCD Method and CEB Method can accurately predict the concrete failure load of fastenings of the full range of investigated applications. On the other hand, depending on the application in question, the predictions of ACI 349-90 and VAC Method are sometimes unconservative and sometimes conservative.

      • KCI등재후보

        LED를 이용한 복합레진의 광조사시, 중합수축의 속도와 양, 미세경도에 관한 연구

        박성호,김수선,조용식,이순영,김도현,장용주,문현승,서정원,노병덕 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.4

        This study evaluated the effectiveness of the light emitting diode(LED) units for composite curing. To compare its effectiveness with conventional quartz tungsten halogen (QTH) light curing unit, the microhardness of 2mm composite, Z250, which had been light cured by the LEDs (Ultralume LED2, FreeLight, Developing product D1) or QTH (XL 3000) were compared on the upper and lower surface. One way ANOVA with Tukey and Paired t-test was used at 95% levels of confidence. In addition, the amount of linear polymerization shrinkage was compared between composites which were light cured by QTH or LEDs using a custom-made linimeter in 10s and 60s of light curing, and the amount of linear polymerization shrinkage was compared by one way ANOVA with Tukey. The amount of polymerization shrinkage at 10s was XL3000 > Ultralume 2, 40, 60 > FreeLight, D1 (P<0.05) The amount of polymerization shrinkage at 60s was XL3000 > Ultralume 2, 60 > Ultralume 2, 40 > FreeLight, D1 (P<0.05) The microhardness on the upper and lower surface was as follows; <본문 참조> It was concluded that the LEDs produced lower polymerization shrinkage in 10s and 60s compared with QTH unit. In addition, the microhardness of samples which had been cured with LEDs was lower on the lower surfaces than the upper surfaces whereas there was no difference in QTH cured samples.

      • KCI등재

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