황칠나무 잎 열수추출물의 Streptozotocin에 의해 유도된 당뇨 흰쥐에서의 항당뇨 효과

김민재 경상국립대학교 보건대학원 2021 국내석사

Dendropanax morbifera Lev. (D. morbifera) is a species of native tree that is widely distributed in the southern parts of Korea including Jeju island. Since ancient times, leaves, stems and roots of the plant have been used as folk remedies to treat dermal complications and other infectious diseases. The present study was conducted to investigate the diabetes treatment effect of the plant hot water extracts (DMWE) using streptozotocin-induced diabetes in rats. In this study, thirty male 5-week-old Sprague-Dawley rats were used. The rats were divided into six groups of five rats per treatment group and administered for 4 weeks. The treatment group were normal control rats received saline (NC), diabetic control rats received saline (DC), diabetic rats treated with 500 mg/kg body weight (BW) of metformin (DT), diabetic rats treated with 50 (DM-50), 100 (DM-100) and 200 mg/kg BW (DM-200) of DMWE. After 14 days of administration of DMWEs, the BW of all groups treated with DMWEs increased significantly compared to that of DC (P<0.05), however, the BW of DM-100 and DM-200 showed no significant difference compared to that of DT. Blood sugar levels in DT and DM-200 decreased below 200 mg/dL at 3 weeks after administration of DMWEs, and at 4 weeks after treatment, blood glucose levels in DT, DM-100 and DM-200 decreased within the normal range. At 4 weeks after treatment of DMWE, the glycated hemoglobin (HbA1c) concentrations in all groups administered with DMWEs showed no significant difference compared to those of NC and DT. The HbA1c concentrations of DM-100 and DM-200 showed significant reduction compared with that of DC (P<0.05). In blood biochemical parameters, the levels of AST, ALT and BUN in DM-100 and DM-200 showed no significant difference compared to those in NC and DT, however, significant differences compared to that of DC (P<0.05). From the above results, DMWEs have been identified to be effective in the treatment of diabetes.

자궁내막증 여성의 질병관련특성과 증상스트레스가 자궁내막증관련 삶의 질에 미치는 영향

박정현 경상대학교 보건대학원 2017 국내석사

This study was conducted to identify factors influencing disease related characteristics and symptom stress on endometriosis quality of life in women with endometriosis by examining relationships among them. The 99 women with endometriosis were collected from one hospital. Data was analyzed using SPSS 21.0 program by frequency, ratio, average, t-test, ANOVA, Scheffé test, Pearson correlation coefficient and stepwise multiple regression analysis. The results of this study were as follows. 1. As a result, the symptom stress level of the factor was 1.19 ± 0.50 (range 0∼3). The average score of the ‘powerlessness' related endometriosis was 2.16 ± 1.04 (range 1~5). 2. In this study, the difference in quality of life related to endometriosis according to the disease-related characteristics of the factor was disease-related illness (t=4.81, p=.000). The difference in quality of life related to illness-related endometriosis was not statistically significant in the case of the factor who experienced sickness due to illness (2.61±0.88) and those who did not experience sickness (1.76±0.75) and the quality of life was low. 3. The results of this study showed that there was a positive correlation (r=.639, p=.000) between the symptom stress of the subjects and the quality of life related to endometriosis. 4. The results of this study indicate that the variables that have a significant effect on the endometriosis health-related quality of life were disease-related illness (β=-.193, p=.011), symptom stress (β=536, p=.000) The higher the symptom stress, the worse the endometriosis related quality of life of the subject. Based on the findings that lower scores of symptom stress would be likely to increase endometriosis qualtiy of life, especially there is a need to develop an endometriosis qualtiy of life program to improve their endometriosis qualtiy of life.

치과위생사의 성희롱 피해 경험과 영향, 성희롱 관련 인식 및 대처

김미은 경상대학교 보건대학원 2015 국내석사

The objective of this study was to identify damaging experiences, effects, knowledge and coping for sexual harassment of dental hygienist's. Data were collected by questionnaires from July 7 to July 31. 2014. To measure knowledge of sexual harassment, the questionnaires developed by Seoul National University's Human Rights Center were utilized. To measure damaging experiences of sexual harassment, the questionnaires developed and modified in the previous study were utilized. To measure effects of sexual harassment, the questionnaires developed and modified in the previous study were utilized. To measure coping for sexual harassment, the questionnaires developed in the previous study were utilized. In this study, the results were summarized as follows: 1. The number of damaging experiences of sexual harassment was 86 persons out of 202 persons (42.6%). 2. Effects on sexual harassment were scored 116.70±25.23 out of 145. Psychological effects were scored 47.44±8.63. Physical effects were scored 41.56±11.37. Effects on jobs were scored 27.89±7.24. 3. Knowledge of sexual harassment was scored 7.52±1.84 out of 11 (68.4%). 4. Coping for sexual harassment was scored 39.30±9.91 out of 80. Directly coping for sexual harassment was scored 24.87±7.92. Indirectly coping for sexual harassment was scored 14.48±3.45. In conclusion, intervention and prevention education program should be developed in order to improve knowledge, minimize effects, and cope for sexual harassment properly.

일개 네트워크 치과 병,의원 치과위생사들의 직무스트레스와 직무만족도가 이직의도에 미치는 영향

고경희 경상대학교 보건대학원 2013 국내석사

Objectives: This study was implemented to propose reducing current dental hygienists' turnover intention by determining that how the job stress and satisfaction influence on their decision. Methods: The study subjects were dental hygienists working in 10 dental clinics belonging to one franchised network in South Korea. The self-administered questionnaires had issued and returned in April 2013 through directors or chief managers of each organization. The tool included 26 items related job stress, 25 items related to job satisfaction, and 6 items related to turnover intention, which were used in the previous studies. Each question was 5 points scale and analysed based on average points. Sociodemographic variables, health related behaviors, and working environment were also measured. Results: The levels of job stress in sub-domains were 3.8 in task, 3.3 in professional position, 3.8 in the relationship with patients, and 3.5 in personal relations, respectively, and total 3.7 in average. In simple analysis overall job stress was significantly higher in those with higher educational level or implementing consultant role. While job satisfaction was significantly higher in those with higher age, being married, higher salary, or longer career, turnover intention was significantly lower in those with higher age, being married, higher salary, or longer career. In multiple regression analysis turnover intention had significant negative association with age and job satisfaction, and positive association with job stress. Those with salary level between 1,500,000 and 1,990,000 won had significantly higher turnover intention than those with lower salary level. As a result of regression analysis by 4 levels verification phase, job satisfaction had a partly mediating effect in terms of relation between job stress and turnover intention. Conclusion: This study suggested strategies to decrease job stress would be required for dental hygienists to bring better job satisfaction and lower turnover intention. Key words: Job stress, Satisfaction, Turnover intention, Dental hygienist

일 지역 금연지원센터에 등록된 중소규모 사업장 남성 근로자의 6개월 금연 성공 요인

류일화 경상국립대학교 보건대학원 2021 국내석사

Objectives: This study aims to identify the factors influenced by examining relation between their sociodemographic characteristics, companies characteristics, smoking-related characteristics, supporters for quitting smoking, and smoking-related psychology. Methods: The subjects of this study were smoking men-workers who had got the visiting services at the G smoking cessation center to stop smoking from January 2018 to December 2020. Total number of the participants was 767 and they were divided into two groups by the size of workplace located in Gyeongsangnam-do: one consisted of 159 workers (20.7%) from 33 small business with less than 50 employees; the other was made up of 608 workers (79.3%) from 42 medium-sized business with from 50 to 300 employees. This study had used the methods such as sociodemographic characteristics (age, educational level, drinking, exercising, chronic illness), smoking-related characteristics (daily average of smoking, smoking duration, nicotine dependence, Attempt to quit smoking), smoking-related psychology(importance of smoking cessation, confidence in smoking cessation, Readiness of smoking cessation), companies characteristics, (the classification of companies, the size of companies, and the will for smoking cessation program of the manager), supporters for quitting smoking( family, co-workers, friends/others.). By using SPSS version 25.0 statistics program, this study analyzed frequency, mean and standard deviation and conducted chi-square test and multiple logistic regression based on the collected data. The outcome was tested by using odds ratio, 95% confidence interval and p-value. The odds ratio greater than 1 means successful smoking cessation and the statistical significance level was based on p < 0.05. Results: The men-workers in small and medium-sized business had a success rate of 20.2% for smoking cessation for 6 months. With multiple logistic regression, the factors causing the differences in the success rate for 6 months of the workers were as follows. The odds ratio of the age under 29, 40~49 was 0.10(95% CI, 0.03-0.29) and 0.43(95% CI, 0.24-0.76) in comparison to the age upper 50. Regarding the average amount of smoking per day, the odds ratio of the group of 11-20 and that of the group more than 21 was 0.52(95% CI, 0.34-0.80) and 0.46(95% CI, 0.24-0.90) respectively, when compared to the group of 1-10. Regarding the supporters for quitting smoking, the odds ratio of group with spouse and other family is 1.99(95% CI, 1.18-3.34) in comparison to the group with no one. Conclusion: This study shows that the chance of success for smoking cessation for 6 months is higher when the subjects have spouses and other family supporters for quitting smoking. And it also shows that the less they smoke a day and the older they are, the more likely it is to succeed in quitting smoking.

일부 중소병원 행정직원의 코로나19 유행에 따른 이직의도와 영향요인 : 근무환경, 직무스트레스, 신체적 피로 및 직무만족을 중심으로

박진숙 경상국립대학교 보건대학원 2022 국내석사

Purpose: This study aims to provide primary data for improvement by identifying the working environment, job stress, physical fatigue, and job satisfaction levels for administrative staff working at medical institutions in the COVID-19 pandemic situation and examining factors affecting job turnover. Methods: In this study, six medical institutions designated as screening and relief hospitals with more than 100 beds and less than 300 beds in the J city area of ​​Gyeongnam Province, except for medical personnel (doctors and nurses) who directly participate in patient treatment, were hospital workers who were working as administrative personnel. Data were collected by using a questionnaire. During the collection period, from October 20, 2021, to October 23, 2021, all 140 copies were collected for 140 people. The collected data were analyzed using SPSS/WIN 23.0 program, and real number and percentage, mean and standard deviation, independent t-test, ANOVA, scheffe test, Pearson correlation coefficients, and hierarchical rarity analysis were used. Results: 1. In terms of demographic, job-related, and COVID-19 work-related characteristics of the participants, there were 111 women (79.3%), the average age was 35.06±10.33 years, 73 'unmarried' status (52.1%). As for the education level, 87 people (62.1%) had ‘college or less’, 65 people (46.4%) from the 'general affairs department', working experience averaged 8.83±9.39 years, and 116 people were 'employee/manager' in the job position. Seventy-seven people replied that the salary level was ‘normal’ (55.0%), 58 people were ‘dissatisfied’ (41.4%), 131 people were ‘regular workers’ (93.6%), and 74 people did not exercise regularly (52.9%). Regarding the health status of the workers compared to the pre-COVID-19 situation, 85 people replied that they were ‘healthy’ (60.7%), 76 people said ‘yes’ to have experienced turnover (54.3%), 69 people have had ‘no contact’ with suspected COVID-19 patients (49.3%) while 55 people have had '1-5 times' of experience (39.3%). Among all participants, 115 people (82.1%) said 'no' for the quarantine experience. Also, as a result of multiple response analyses for increased work after the outbreak of COVID-19, 112 people have gone through ‘Fever check’ (80.0%). 2. Looking at the participants’ working environment, job stress, physical fatigue, job satisfaction, and turnover intention, the average score of working environment was 3.16±0.50 out of 5, and 'institutional support' among the sub-factors was the lowest at 2.63±0.67. For job stress, the average score was 3.28±0.53 out of 5, and 'risk of infection' was the highest with 3.51±0.79 points. The average score for physical fatigue was 3.01±0.65 out of 5, and in particular, ‘difficulty due to new roles and demands’ scored 3.16±0.68 points, which corresponded to factors with high physical fatigue. The average scores of job satisfaction and turnover intention were 2.84±0.70 and 3.04±0.76 out of 5, respectivley. 3. As a result of examining the differences in the working environment, job stress, physical fatigue, job satisfaction, turnover intention according to the characteristics of the participants, it was found that if they were satisfied with the salary level, they perceived the working environment as good. However, those who categorized their salary level as 'normal' and 'dissatisfaction' were bound to have higher job stress, physical fatigue, and job satisfaction. Turnover intention differed according to which rank they belonged to; ‘employees and managers’ had higher turnover intention than ‘chief’ and ‘agent level or higher,’ while ‘discontent’ had higher turnover intention than ‘satisfaction’ and ‘normal’ in monthly salary level. 4. As a result of analyzing the correlation between the participants’ working environment, job stress, physical fatigue, job satisfaction, turnover intention, the turnover intention had a negative correlation with the working environment (r=-.63, p<.001) and job satisfaction (r=-.58, p<.001), and positive correlation with job stress (r= .30, p<.001) and physical fatigue (r= .49, p<.001). 5. As a result of hierarchical regression analysis to find out the effect of the subject's work environment, job stress, physical fatigue, and job satisfaction on turnover intention, the variable that had a significant effect on turnover intention was physical fatigue (ß=.31. p<.001), dissatisfaction with salary level (ß=.26, p<.001), working environment (ß=-.24, p=.003), job satisfaction (ß=-.23, p=.001) in order. In other words, the higher the physical fatigue, the higher the dissatisfaction with the salary level, the worse the working environment, and the lower the job satisfaction, the higher the turnover intention. The total explanatory power of these variables explaining turnover intention was 60.9% (F=22.46, p<.001, R2=.609, Adj-R2=.582). Conclusion: In this study, the factors affecting the turnover intention of the administrative staff of small and medium hospitals in the context of COVID-19 in this study were physical fatigue, satisfaction with salary level, working environment, and job satisfaction. The increased workload of hospital administrative staff concerning COVID-19 patients increases physical fatigue, which is expected to increase turnover intention. In addition, dissatisfaction with salary level, working environment, and the job was found to be a factor that increased turnover intention. Therefore, it is necessary to change administrative staff’s salary level and compensation system in small and medium-sized hospitals.

코로나19 발생 및 유행정도가 경남주민의 건강행태 및 우울감에 미치는 영향

서영미 경상국립대학교 보건대학원 2023 국내석사

Objectives: This study aims to investigate the influence factors by examining the relationship between the occurrence and prevalence of COVID-19 on the health behavior (smoking, drinking, physical activity) and depression of Gyeongnam residents using the natural test situation of COVID-19. Methods: This study was analyzed using raw data from the Gyeongsangnam-do Community Health Survey. A total of 35,880 people (17,942 people in 2019, 17,938 people in 2020) were used for the analysis, and all data were analyzed using SPSS 25.0. The effect of COVID-19 on the health behavior and depression of Gyeongnam-do residents was investigated by dividing it into Before and after COVID-19 outbreak and prevalence rates. General characteristics were investigated through descriptive statistical analysis, and changes in health behavior and depression in 2019-2020 were analyzed using t-test and χ² test. Multiple logistic regression analysis was used to investigate the correlation between changes in health behavior and depression and the occurrence of COVID-19 in Gyeongnam-do residents. In addition, through multilevel logistic regression analysis, regions with a high incidence rate and regions with a low incidence rate were classified to check whether there were differences in health behavior and depression between regions. All statistical significance levels were based on p<0.05. Results: Comparison results before and after the outbreak of COVID-19, The rate of smoking cessation attempts significantly decreased after the outbreak of COVID-19 compared to before the outbreak (p<0.001). The monthly drinking rate decreased after the outbreak of COVID-19 (p<0.001). However, the high-risk drinking rate increased after the outbreak of COVID-19 (p<0.001). The rate of walking practice increased after the outbreak of COVID-19 (p<0.001). As for the rate of experiencing depression, the rate of experiencing depression after the outbreak of COVID-19 increased (p<0.001). The prevalence of depressive symptoms also increased after the onset of COVID-19 (p=0.001). As a result of comparing regions by the difference in the incidence of COVID-19, the monthly drinking rate was higher in regions with a large number of confirmed cases than in regions with rare occurrences (p=0.017). As for the experience rate of depression, the rate of experiencing depression was higher in the area with a high incidence than the area with a rare occurrence (p<0.001), and the prevalence of depression was also higher in the area with a high incidence (p<0.001). Conclusion: This study shows that the occurrence of COVID-19 affects the health behavior and depression of residents in Gyeongnam, and there is a difference in health behavior and depression between regions according to the incidence of COVID-19.

강황 추출물의 주요 식중독균에 대한 항균효과 및 독성 (급성경구독성, 피부자극성) 평가

이다영 경상대학교 보건대학원 2020 국내석사

본 연구는 식품의 착향료와 조미료 그리고 식품에 노란색을 부여하는 천연향신료 등으로 사용되고 있는 강황의 메탄올 추출물을 이용하여, 주요한 식중독 세균들인 S. aureus, S. typhimurium, E. coli O157:H7 등에 대한 항균활성시험, 마우스와 토끼에서의 급성경구독성시험, 토끼를 이용한 피부자극성시험 등을 수행하였다. 항균활성시험 결과, S. aureus, S. typhimurium, E. coli O157:H7에 대한 강황 추출물의 최소억제농도는 각각 0.250, 0.250, 0.125 mg/kg이었으며, 최소살균농도는 각각 0.50, 0.50, 0.25 mg/kg으로 나타났다. 편백 정유를 마우스에 0, 125, 250, 500, 1,000, 2,000 mg/kg body weight (BW)의 농도로 각각 1회 경구투여하였으며, 토끼에는 0, 1,000, 2,000 mg/kg BW의 농도로 각각 1회 경구투여한 결과, 마우스와 토끼 모두 2,000 mg/kg BW에서 모두 생존하였으며, 모든 투여군의 체중 및 모든 혈액학적·혈액생화학적 지표값들이 대조군과 비교하여 통계적으로 유의적인 차이를 보이지 않았다. 따라서 강황 추출물의 마우스와 토끼에서의 반수치사량 (lethal dose 50, LD50)은 2,000 mg/kg BW 이상으로 확인되었다. 토끼를 이용한 강황 추출물의 피부자극성시험 결과, 일차피부자극지수가 0.13으로 나타나, 강황 추출물은 피부에 자극성이 없는 물질로 확인되었다. 이상의 실험결과로부터, 강황 추출물은 S. aureus, S. typhimurium, E. coli O157:H7에 대해 항균활성을 갖고 있으면서, 급성독성과 피부자극성이 없는 물질로 식품보존제 및 화장품 등에 적용할 수 있는 안전한 물질로 확인되었다.

문재인 케어 정책에 대한 기간별 인터넷 기사 댓글 분석 : 텍스트 마이닝 활용

윤현준 경상대학교 보건대학원 2019 국내석사

본 연구는 텍스트 마이닝을 활용하여 문재인 케어 관련 인터넷 기사 댓글들을 해당 정책 발표일인 2017년 8월 9일부터 2018년 12월 31일까지 수집하여 전체기간과 분기별로 빈도분석과 연관 규칙 분석을 시행하여 문재인 케어에 대한 여론 변화를 파악하고자 실시한 연구이다.

간호사의 교대근무가 수면의 질, 주간졸음 및 간호업무 중 인지한 오류 경험에 미치는 영향

김미성 경상대학교 보건대학원 2013 국내석사

Objectives: The objective of this study was to identify the influence of shift work on sleep quality, daytime sleepiness, and perceived errors in nursing work among hospital nurses. Methods: The study subjects were 209 hospital nurses working in two general hospitals in South Korea. The data were collected through self-administered questionnaires in May 2013. Sleep quality was measured with Korea Pittsburgh Sleep Quality Index (PSQI-K), daytime sleepiness with Epworth Sleepiness Scale (ESS), and perceived errors in past 6 months in nursing work with the tool developed in this study. Results: The sleep quality was significantly worse in rotating shift nurses than fixed day nurses. However, the odds ratio (OR) of 1.92 [95% confidence interval(CI): 0.58-6.37] adjusted for sociodemographic variables, health behaviors, and working environment in logistic regression was not significant. There was no significant difference in the daytime sleepiness between rotating shift nurses and fixed day nurses in both simple and multivariable analyses. There were significantly more perceived errors in rotating shift nurses than fixed day nurses. However, the OR of 1.26 (95% CI: 0.38-4.21) adjusted for sociodemographic variables, health behaviors, working environment, sleep quality, and daytime sleepiness in logistic regression was not significant. Depression (OR=3.31, 95% CI: 1.11-9.84) and daytime sleepiness(OR=1.18, 95% CI: 1.07-1.30) were significantly associated with perceived errors in logistic regression. Conclusion: This study suggested shift work among hospital nurses had no independent influence of sleep quality, daytime sleepiness, and perceived errors. However, daytime sleepiness had independent influence of perceived errors. More studies are warranted to get more reliable conclusion. Key words: Rotating shift nurses, Nursing work, Clinical nurses, PSQI-K