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      • 웨이트 트레이닝이 갱년기 여성의 유산소성 파워와 골밀도에 미치는 영향

        최성수 조선대학교 환경보건대학원 2004 국내석사

        RANK : 247631

        The purpose of this study was to investigate the effect of weight traing exercise on the prevention of the osteoporosis. With the subject of middle-aged women(exercise group=10, control group=10), the aerobic and weight load exercise of weight training was administered for 24 weeks(4 times a week, each for 60 min.) at the work intensity of 50∼60%. Then their aerobic power, bone mineral density and mass, hormone, serum calcium and serum phosphate were calculated to bring about the following results. The results of this study were as follows; 1. The subject's age averaged 54.63 ±2.67(training group) and 54.25±2.33(control group). 2. Training group showed no change of weight through the exercise but decrease in %fat and increase in LBM. But, the control group had no change of weight after the exercise but increase in %fat and decrease in LBM. 3. The heart rate of weight traing group at rest decreased, while Vo₂ max, Vo₂max/weight, and Met max increased significantly(p<0.005, p<0.005, p<0.004). But, control group's heart rate at rest increased, while Vo_(2) max, Vo_(2) max/weight, and Met max decreased. 4. Training group increased in BMD at the part of lumbar 2-4, femoral neck, and ward's triangle but there is no change at femoral troch. But control group's BDM decreased at that four part. 5. The serum Ca level and serum P level of training group increase significantly(p<0.01, p<0.01), but PTH-intct and deoxypyridinoline decreased. But serum Ca level and deoxypyridinoline of control group decreased, while alkaline phosphatase, serum P level, and PTH-intact increased. As a result, weight trainig exercise was effective in increasing Vo₂max, decreasing HR at rest, helping long-endurance exercise, and maintaning high BMD. Further research is required for the correct exercise prescription and exercise threshold to work off middle-aged women's osteoporosis.

      • 119 구급대원의 직무관련 특성과 외상 후 스트레스가 직무만족도에 미치는 영향

        최성수 조선대학교 2015 국내박사

        RANK : 247631

        Objective : The purpose of this study was to investigate the current status of job satisfaction, post-traumatic stress (PTS) and associated factors with job satisfaction among 119 rescue workers. Methods : The study subjects were 507 rescue workers who worked in G Metropolitan City and J province. General characteristics, job-related characteristics, PTS and job satisfaction were collected by self-reported questionnaires via official e-mail. Job satisfaction by subjects' characteristics were tested by t-test, ANOVA, and multiple regression analysis. Results : Of 507 rescue workers, the overall PTS scores and job satisfaction score were 13.58±12.99 and 85.19±13.37, respectively. In multiple regression analyses, job satisfaction score were significantly lower in subjects with fair (β=-3.53, p=0.003) or poor (β=-7.69, p=<0.001) self rated health and with longer duration of career (β=-3.53, p=0.025). With regard to rescue field related characteristics, witness of injury of co-workers (β=-3.02, p=0.022), obvious dead treatment (β=-3.60, p=0.011) and PTS (β=-4.21, p=0.013) were associated with lower job satisfaction. Conclusion : Job satisfaction were associated with general characteristics, field related factors and PTS. Risk reduction of rescue field and management of PTS will help to increase the job satisfaction of 119 rescue workers. key words: Job satisfaction, Post-traumatic stress, 119 rescue workers

      • The Effect of Quercetin on the Bioavailability of Tamoxifen in Rats

        최성수 조선대학교 대학원 2005 국내석사

        RANK : 247631

        The aim of this study was to investigate the effect of quercetin on the bioavailability of tamoxifen after oral coadministration of tamoxifen (10 mg/kg) with quercetin (1.5, 7.5, 15 mg/kg) or pretreatment of quercetin (1.5, 7.5, 15 mg/kg) 30 min prior to tamoxifen. Coadministration of 1.5 and 7.5 mg/kg of quercetin significantly altered the pharmacokinetic parameters of tamoxifen, but not by 15 mg/kg of quercetin. Compared with the control group, coadministration of 7.5 mg/kg of quercetin significantly (p<0.05) increased the absorption rate constant (Ka) and the peak concentration (Cmax) of tamoxifen, and the areas under the plasma concentrations of tamoxifen were significantly higher by coadministration of 1.5 and 7.5 mg/kg of quercetin. The absolute bioavailability (AB%) of tamoxifen in control group was 25.6%, which were 29.5-39.3% by coadministration, increased significantly (p<0.05) for 1.5 and 7.5 mg/kg of quercetin. Relative bioavailability (RB%) of tamoxifen by coadministration was from 1.18-to 1.54-fold increased. There were not apparent changes in the time to reach peak concentration (Tmax) and terminal half-life (t½) of tamoxifen. On the other hand, pretreatment of quercetin altered the parameters more compared to the coadministration by increasing the dose of quercetin. Ka, Cmax and AUC were increased significantly (p<0.05 for 1.5 mg/kg, p<0.01 for 7.5 and 15 mg/kg) compared to the control group. Followed with the significantly increased AB% of tamoxifen (p<0.05 for 1.5 mg/kg, p<0.01 for 7.5 and 15 mg/kg, 42.1-51.4%). Same as coadministration, both Tmax and t½ of tamoxifen were not altered significantly. The increased oral bioavailability of tamoxifen in the presence of quercetin might be due to the quercetin as a dual inhibitor of P-glycoprotein and CYP 3A4 to promote the systemic exposure of tamoxifen. If it is further confirmed in the clinical setting, the tamoxfen dosage should be taken into consideration while tamoxfen is used concomitantly with quercetin or the dietary supplement full of quercetin. 본 연구의 목적은 quercetin(1.5, 7.5, 15 mg/kg)으로 병용 혹은 0.5시간 전 투여한 흰쥐에게 타목시펜(10 mg/kg)을 경구투여 하였을 때 타목시펜의 생체이용률에 미치는 영향을 연구하였다. quercetin 동시투여군에서 타목시펜의 약물동태학적 파라메터는 대조군에 비해 유의성 있게 변화 하였다(15 mg/kg제외). quercetin 7.5 mg/kg을 동시투여한가토에서 타목시펜의 흡수속도정수(Ka) 및 최고혈장중농도(Cmax)는 대조군에 비해 유의성(p<0.05) 있게 증가하였으며, 혈장농도곡선하면적(AUC)은 1.5 및 7.5 mg/kg에서 유의성(p<0.05) 있게 증가하였다. 대조군에서 타목시펜의 절대적생체이용률(AB%)은 25.6%이었으며, 병용투여군에서는 29.5-39.3%로 증가하였고 1.5 및 7.5 mg/kg에서 유의성(p<0.05)이 있었다. 상대적생체이용률(RB%)은 대조군에 비해서 1.18-1.54배로 증가하였다. 최고혈중농도도달시간(Tmax)과 소실반감기(t½)는 유의성있는 변화를 보이지 않았다. quercetin 0.5시간 전 투여군에서 타목시펜의 약물동태학적 파라메터는 동시투여군에 비해 더욱 큰 변화를 보여주었으며 그 변화는 quercetin의 투여량을 증가함에 따라 커졌다. quercetin 전 투여군에서 타목시펜의 Ka, Cmax 및 AUC은 대조군에 비해 모두 유의성(p<0.05 at 1.5 mg/kg, p<0.01 at 7.5 and 15 mg/kg) 있게 증가하였다. 그 결과 전 투여군에서 AB%는 42.1-51.4%로 유의성(p<0.05 at 1.5 mg/kg, p<0.01 at 7.5 and 15 mg/kg) 있게 증가하였다. Tmax 및 t½는 동시투여군에서와 같이 유의성 있는 변화를 보이지 않았다. 본 연구에서 타목시펜을 항암작용이 있는 quercetin과 흰쥐에게 병용투여하였을 때 타목세펜의 생체이용률은 현저히 증가하였다. 퀠시틴은 장관 및 간에서 다제내성물질(Multi-drug resistant substance)인 P-당단백질과 대사 효소인 CYP 3A의 억제로인하여 경구투여한 타목시펜의 first-pass effect를 감소시켜 그의 생체이용률이 증가한 것으로 사료된다. 임상치료에서 타목시펜을 quercetin 혹은 quercetin을 함유한 음식물과 함께 병용할 때 이들의 약물동태학적 상호작용을 고려하는 것이 바람직하다고 사료된다.

      • 감자의 삽목번식과 품종별 생육 비교

        최성수 순천대학교 교육대학원 2009 국내석사

        RANK : 247631

        The objective of the present study was to find effective potato multiplication methods. In general, a desirable cottage medium is soil with low fertilizer content and high water holding capacity and air permeability. Because field soil contained too much fertilizer for potato cuttage, it was not suitable as a cuttage medium, and the rooting rate of perlite, which has high water holding capacity and air permeability, was satisfactory compared to that of other media. The media with the highest rooting rate were nursery soil and vermiculite, and nursery soil was better than vermiculite in terms of root count and the length of the longest root. Although it contained fertilizer, nursery soil showed a high rooting rate of potato cuttage. In the stem cuttage of potato, medium prepared by mixing nursery soil and vermiculite is considered suitable as it contains some fertilizer and has high water holding capacity and air permeability. The parts desirable for cuttage are the first node and the second node. There was little difference in rooting rate between the first node and the second node. It is believed that nodes in the upper part have shoots and are young, so they grow fast and show a high rooting rate. In terms of the number of leaves, cuttages with 3 leaves showed a rooting rate of 100% and those with 2 leaves showed 90%. Thus, it is advantageous to use cuttages with 3 leaves, and it is considered desirable to get cuttages from nodes with 2~3 leaves in the upper part. According to time, cuttages obtained in April showed a far higher rooting rate than those in March. It is believed that temperature is higher in April than in March and the high temperature has a positive effect on the rooting of cuttages. Photoperiod was not controlled in our experiment, but it may be necessary to examine the effect of photoperiod on cuttage according to time. From 24 days from cuttage, we could see rooting with the naked eye. As to the formation of potato tubers, the number of tubers was largest in nursery soil according to medium, in cuttages obtained from the second node according to the part of stem, in cuttages with 4 leaves according to the number of leaves, and in cuttages obtained in March according to cuttage time. This suggests that the formation of tubers is highly affected by the conditions of cuttage cultivation such as water, temperature and nutrients. In addition, the stem cuttage of potato showed the formation of tubers that cannot see in the cuttages of other plants. It is probably because potato is originally formed as the stem is enlarged and thus tubers can be formed if the stem is cut. In potato cultivation using seed potatoes, however, tubers are formed from buds between the stem above the ground and leaves because the buds sense low?]temperature short days inadequate for vegetative grow, and in case seed potatoes are cultured in high?]temperature long days, they show only the active vegetative growth of the part above the ground. In seed potato multiplication, the size of seed potatoes within the same variety did not affect the growth and yield of the potatoes. That is, growth and yield were little different between potatoes grown from large seed potatoes and those from small seed potatoes. Therefore, it is not necessary to prefer large seed potatoes in seed potato multiplication. The present study was conducted in order to investigate change in the growth of potato stem cuttages according to medium, change in calluses and tubers of cuttages, change in the number of leaves on cuttages, change according to cuttage time, and growth and yield according to seed potato type, to examine how these factors affect the productivity and growth of cuttages, and ultimately to contribute to the production of highly efficient good potato seedlings. Lastly, as to the growth and yield of potato according to variety, we conducted an experiment with six varieties (Daeji?]Dae, Daeji?]So, Chubaek?]Dae, Chubaek?]So, Sumi, and Daeseo). Daeji?]So grew taller and better than Daeji?]Dae and, next, in order of Chubaek?]So, Chubaek?]Dae, Daeseo, and Sumi. The yield of potato was highest in Daeseo, which was followed by Daeji?]So, Daeji?]Dae, Chubaek?]Dae, Chubaek?]So and Sumi. As presented above, the size of seed potatoes within the same variety hardly affected the growth and yield.

      • 드론 배송 서비스 사용 의도에 영향을 미치는 요인에 관한 연구

        최성수 숭실대학교 2019 국내박사

        RANK : 247631

        According to BIS Research's market analysis, the global UAV(Unmanned aerial vehicle) market is expected to grow 9% CAGR(Compound Annual Growth Rate) in 2018 from 2014, and the domestic UAV market will grow 9% CAGR in 2018 from 2014. Gartner's recent analysis shows that technology innovation is accelerating in four areas: block chains, brain-computer interfaces, API-based software definition security, and commercial drone. In particular, for commercial UAVs, AI(Artificial Intelligence) Hardware and computing power, and advances in technology of deep-learning algorithms, it is expected to be usefully used in various industries such as financial services and manufacturing. On the other hand, the process from raw material procurement to production is called First-Mile Logistics, and the process of supplying manufactured products to end customers is called Last-Mile Logistics. In the existing logistics system, as the demand for improvement in the delivery time and the delivery speed of the consumer grows, it is expected that the person who catches the Last Mile will be the leader of the logistics and oil statistics. Amazon's Amazon, China's Sung Feng Xuwen (SF Express) and Ying Ding (JD.com) are breaking down the boundaries between distribution and logistics to boost corporate brand power and competitiveness, and are making major investments. In this trend, Last Mile Delivery using drones is emerging. Consumer awareness surveys by the US Postal Inspection Service (OIG) on dron courier indicate that US consumers expect drones to be commercialized within the next five to ten years (75%), but they still believe in drone delivery technology and safety (37%). Although research on the delivery of drones is emerging as an issue in the field of shipping services, most studies on technical research, policy and development direction are mostly conducted, and empirical studies on the factors of using dron shipping service for actual users It was a slight situation. In order to verify the factors affecting the intention to use the service of the unmanned airplane from the point of view of the user, we summarized the status of UAV and delivery service using the UAV, and the study model (UTAUT) The results were analyzed using the SPSS and AMOSS statistical programs based on the questionnaire. The results of this study are not sufficient. However, we hope that in the upcoming drones delivery service market, based on an accurate analysis of the usage factors that real users want, we will be able to give higher value to our customers and gain a better service to our customers. BIS(Bank for International Settlements) Research의 시장분석에 따르면 전 세계적 UAV(Unmanned aerial vehicle) 시장 규모는 2014년보다 2018년 CAGR(Compound Annual Growth Rate) 9% 성장할 것으로 전망하고, 국내 UAV 시장 규모는 2014년보다 2018년 CAGR 9% 성장할 것으로 전망하고 있다. Gartner 최근 분석에 따르면, 블록체인, 뇌-컴퓨터인터페이스, API(Application Programming Interface) 기반 소프트웨어 정의 보안, 상용 드론 이렇게 4개 분야에서의 기술혁신이 가속화되고 있다고 한다. 특히, 상용 드론(Commercial UAVs)의 경우, AI(Artificial Intelligence), 하드웨어, 컴퓨팅 파워의 소형화, 딥-러닝 알고리즘의 기술 진보로 금융 서비스, 제조 분야 등 다양한 산업에서 지속적으로 유용하게 적용될 것으로 예상한다. 한편 원자재 조달에서 생산에 이르는 프로세스를 First-Mile Logistics라고 부르고, 생산된 제품을 최종고객에게 공급하는 프로세스를 Last-Mile Logistics라고 한다. 기존 물류 시스템에서 소비자의 배송 시간 및 배송 속도에 대한 개선요구가 커지면서 Last Mile을 잡는 자가 물류·유통계의 강자가 될 것으로 전망되고 있다. 미국의 아마존, 중국의 순펑쑤윈(SF익스프레스)과 징둥(JD닷컴) 등이 유통과 물류 간의 경계를 허물고 있으며, 대규모 투자를 진행하고 있다. 이러한 흐름 속에서, 드론을 활용한 Last Mile Delivery가 부상하고 있다. 미국 우편검사국(OIG)의 드론 택배에 관한 소비자 인식조사에 따르면, 미국 소비자들은 드론 배송 서비스가 앞으로 5~10년 이내에 상용화될 것으로 예상하나(75%), 아직까지는 드론 택배 서비스의 기술과 안전성에 대해서는 신뢰하지 못하는 것(37%)으로 조사되고 있다. 드론 배송 관련 연구는 최근 배송 서비스 분야의 이슈로 떠오르고 있지만 주로 기술적인 연구와 정책과 발전 방향에 관한 연구가 대부분을 차지하고 있으며 실사용자를 대상으로 하는 드론 배송 서비스를 사용하고자 하는 요인에 관한 실증적 연구는 미미한 실정이었다. 본 연구는 사용자 관점에서 드론 택배 서비스에 대한 사용 의도에 미치는 요인을 검증하기 위해 드론과 이를 활용한 배송 서비스 현황과 발전과정을 정리하고 선행 연구한 통합기술수용이론(UTAUT)를 이용하여 연구모델과 가설을 설정하고 설문을 통하여 수집된 350부의 설문 응답 집을 바탕으로 SPSS, AMOSS 통계 프로그램을 활용하여 검증하고 분석 결과를 도출하였다. 본 연구의 결과를 통하여 부족하지만, 앞으로 다가올 드론 배송 서비스 시장에서 실사용자가 원하는 사용요인에 대한 정확한 분석을 바탕으로 이를 준비하는 기업 혹은 우정사업본부가 세계적으로 경쟁하고 있는 각국의 드론 배송 서비스 시장에서 서비스 우위를 확보하여 고객에게 더 높은 서비스와 가치를 제공하고 고객이 더욱더 쉽게 서비스를 사용할 수 있게 되기를 희망해 본다.

      • 감자의 삽목번식과 품종별 생육 비교

        최성수 순천대학교 교육대학원 2009 국내석사

        RANK : 247631

        The objective of the present study was to find effective potato multiplication methods. In general, a desirable cottage medium is soil with low fertilizer content and high water holding capacity and air permeability. Because field soil contained too much fertilizer for potato cuttage, it was not suitable as a cuttage medium, and the rooting rate of perlite, which has high water holding capacity and air permeability, was satisfactory compared to that of other media. The media with the highest rooting rate were nursery soil and vermiculite, and nursery soil was better than vermiculite in terms of root count and the length of the longest root. Although it contained fertilizer, nursery soil showed a high rooting rate of potato cuttage. In the stem cuttage of potato, medium prepared by mixing nursery soil and vermiculite is considered suitable as it contains some fertilizer and has high water holding capacity and air permeability. The parts desirable for cuttage are the first node and the second node. There was little difference in rooting rate between the first node and the second node. It is believed that nodes in the upper part have shoots and are young, so they grow fast and show a high rooting rate. In terms of the number of leaves, cuttages with 3 leaves showed a rooting rate of 100% and those with 2 leaves showed 90%. Thus, it is advantageous to use cuttages with 3 leaves, and it is considered desirable to get cuttages from nodes with 2~3 leaves in the upper part. According to time, cuttages obtained in April showed a far higher rooting rate than those in March. It is believed that temperature is higher in April than in March and the high temperature has a positive effect on the rooting of cuttages. Photoperiod was not controlled in our experiment, but it may be necessary to examine the effect of photoperiod on cuttage according to time. From 24 days from cuttage, we could see rooting with the naked eye. As to the formation of potato tubers, the number of tubers was largest in nursery soil according to medium, in cuttages obtained from the second node according to the part of stem, in cuttages with 4 leaves according to the number of leaves, and in cuttages obtained in March according to cuttage time. This suggests that the formation of tubers is highly affected by the conditions of cuttage cultivation such as water, temperature and nutrients. In addition, the stem cuttage of potato showed the formation of tubers that cannot see in the cuttages of other plants. It is probably because potato is originally formed as the stem is enlarged and thus tubers can be formed if the stem is cut. In potato cultivation using seed potatoes, however, tubers are formed from buds between the stem above the ground and leaves because the buds sense low?]temperature short days inadequate for vegetative grow, and in case seed potatoes are cultured in high?]temperature long days, they show only the active vegetative growth of the part above the ground. In seed potato multiplication, the size of seed potatoes within the same variety did not affect the growth and yield of the potatoes. That is, growth and yield were little different between potatoes grown from large seed potatoes and those from small seed potatoes. Therefore, it is not necessary to prefer large seed potatoes in seed potato multiplication. The present study was conducted in order to investigate change in the growth of potato stem cuttages according to medium, change in calluses and tubers of cuttages, change in the number of leaves on cuttages, change according to cuttage time, and growth and yield according to seed potato type, to examine how these factors affect the productivity and growth of cuttages, and ultimately to contribute to the production of highly efficient good potato seedlings. Lastly, as to the growth and yield of potato according to variety, we conducted an experiment with six varieties (Daeji?]Dae, Daeji?]So, Chubaek?]Dae, Chubaek?]So, Sumi, and Daeseo). Daeji?]So grew taller and better than Daeji?]Dae and, next, in order of Chubaek?]So, Chubaek?]Dae, Daeseo, and Sumi. The yield of potato was highest in Daeseo, which was followed by Daeji?]So, Daeji?]Dae, Chubaek?]Dae, Chubaek?]So and Sumi. As presented above, the size of seed potatoes within the same variety hardly affected the growth and yield.

      • 페로브스카이트 양자점 기반 색변환 섬유를 이용한 고효율 유기발광소자

        최성수 한양대학교 대학원 2023 국내석사

        RANK : 247631

        플렉서블 OLED 디스플레이 기술 발전으로 인해 인체친화적 발광 소자에 대한 응용 기술의 필요성이 대두되었고, 웨어러블 디스플레이의 심화된 기술 연구가 활발히 진행되고 있다. 관련 연구 분야로 해외 연구소 및 산업체를 중심으로 하여 섬유를 기반으로 하는 OLED 소자의 기술 개발이 이뤄지고 있다. 안정적인 효율의 섬유 기반의 디스플레이 소자를 제작하기 위해서는 평평한 표면 상태를 유지하여 일정한 엑시톤의 형성을 유도하여 발광 강도를 높여야 할 필요성이 있다. 그러나, 일반 섬유 직물 조직의 표면 거칠기는 상당히 좋지 않아 열등한 발광 능력을 갖게 된다. 따라서, 평평한 표면 상태를 유지하면서 투명한 특성을 갖고 우수한 물리 광학적 특성을 갖는 Urethane 기반의 광 경화성 고분자 수지를 응용한 연구를 진행하였다. 본 논문에서는 광 경화성 고분자 수지와 함께 페로브스카이트 양자점을 번갈아 삼중층으로 구성하여 광학적으로 우수한 복합 색변환층을 제작하였다. 광 경화성 고분자 수지를 기반으로 한 복합 색변환층은 세 가지의 이점이 있다. 우선, 광 경화성 고분자 수지는 투명한 고상의 물질로써 섬유 직물에 Dip-coating 방식을 통해 증착 하여 균일한 표면 상태를 갖게 하는 효과를 지닌다. 두 번째 이점은, 광 경화성 고분자 수지에 일정 수준의 열처리를 가하여 그물망 구조(Micro-structure)를 형성하여 구조 내에 페로브스카이트 양자점을 흡수시켜 OLED 소자의 발광원이 입사하였을 때, 빛을 더 오랜 기간 머물게 하여 발광 강도를 높이는 효과를 지닌다. 세 번째 이점은, 유기물 증착 전 광 경화성 고분자 수지를 한 번 더 코팅하여 페로브스카이트 양자점을 외부의 먼지 및 열로부터 보호하여 내구성을 증진시키는 효과를 갖는다. 이와 같이 구성된 복합 색변환층은 빛의 산란 효과를 높여 외부양자효율(EQE)의 향상을 유도하였다. 별도의 복잡한 공정과정 없이 복합 색변환층을 구성함으로써 유기물 시료의 안정적인 표면 흡착 상태를 보장하였고, 광 경화성 고분자 수지의 경화 과정에서 다른 경화공정에 비해 부대비용이 현저히 낮고 기판에 손상을 가하지 않아 신뢰성과 경제성이 보장된 섬유 기반의 플렉서블한 OLED 소자를 제작하였다. 본 연구를 통해, 두꺼운 Plastic 재질의 복합 평탄화층보다 안정적인 빛의 산란 및 플렉서블한 특성, 스트레처블한 특성에서 우월한 광학적, 기계적 성질을 갖는 섬유 기반의 발광 소자를 제작하는 소기의 성과를 달성하였다. 이와 같은 연구 결과는 향후 섬유 기반의 Flexible OLED 소자 응용 기술 연구에 긍정적인 영향을 미칠 것으로 예상한다.

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