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RISS 인기검색어
- 검색키워드
- 저자 : 윤달식 (검색결과 2 건)
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정기 건강검진 수진자의 간기능 수준에 따른 생활습관 변화
윤달식 충남대학교 보건ㆍ바이오산업기술대학원 2007 국내석사
In order to control the patients suffering from the liver efficiently and lower the rate of occurrence by observing the obesity, smoking, drinking, and the change of exercise habit as well as watching closely the effect that the life habitual change has on the LFT mean value and the liver function abnormal ratio change, this research was carried out on 4092 people who took a medical checkup at Korea Association of Health in Taejon-Chungnam province in 2002 and 2004. The contents of the research cover drinking, smoking, exercise, and obesity degree change and the items of a medical checkup were AST, ALT, GGT and LFT putting together three items. The major results are as followings; 1. Compared to 2002, in 2004 there was a decrease in BMI ratio, smoking ratio, and alcohol drinking ratio by 1.6%, 1.9%, 0.7% respectively, whereas there was a increase in the group taking regular exercise by 2.6%. 2. Compared to 2002, in 2004 there was a decrease in the LFT mean value; AST, ALT, and GGT by 1.56IU/L, 0.66IU/L, 3.94IU/L respectively. 3. Compared to 2002, in 2004 there was a decrease in the liver function abnormal ratio; AST, ALT, GGT, and LFT by 1.8%, 0.3%, 2.7%, 2.4% respectively. 4. In the life style change by the liver function level, there was a significant decrease in BMI ratio; 1.4% in the normal group / 3.0% in the abnormal group, smoking ratio; 1.9% in the LFT normal group / 2.5% in the abnomal group, and drinking ratio; 0.3% in the LFT normal group / 3.6% in the abnormal group. On the other hand, there was a slight increase in the group doing regular exercise; 2.4% in the LFT normal group / 3.6% in the abnormal group. 5. The LFT risk by life style was 4.757 times higher in the male than in the female in 2002, 3.775 times in 2004; 3.264 times higher in the obesity group than in the group having normal weight in 2002, 3.891 times in 2004; 2.923 times higher in the group having a smoke than in the nonsmoker group in 2002, 2.744 times in 2004; 3.294 times higher in the group having a drink than in the nondrinker group in 2002, 2.455 times in 2004; 1.158 times higher in the regular exercise group than in the irregular exercise group in 2002, 1.105 times in 2004, but it doesn't matter in terms of statistical figures. 6. In order to investigate the effects that the gender and daily life style can have on the results of AST, ALT, GGT, multivariate regression analysis conducted was as followings; the gender, obesity degree, smoking, drinking, and whether or not to take exercise were the significant variable of AST and ALT. whereas the gender, obesity degree, smoking, and drinking were the significant variable of GGT.
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일부 정기 건강검진 남자 수진자의 음주, 비만별 간기증 수준변화 추적연구
In order to observe the effect that BMI and drinking habit of some males taking a periodic medical checkup has on the LFT mean value and the liver function abnormal ratio change, this research was carried out on 581 people who took a medical checkup at Medical Checkup Center in 2002, 2004, 2006, and 2008. The contents of the research cover drinking and BMI and the items of medical checkup were AST, ALT, GGT, and LFT which achieved comprehensive judgment of the three items. The major results are as follows. The drinking rate and obesity rate had decreased by 5.5%, 6.0%, respectively in the end year compared to the starting year of research, and drinking habits of normal liver function group in starting year of research had reduced in 2008 compared to 2002, but AST and ALT had increased in abnormal liver function group, while ALT had reduced. Obesity rate had decreased in both normal and abnormal liver function group, but showed greater decrease in abnormal liver function group. Average rate of AST, ALT, GGT significantly decreased by 16.1%, 21.1%, 4.6% respectively, and AST, ALT LFT liver function abnormal rate had decreased by 4.9%, 5.9%. In case of age level, AST, ALT, GGT average rate and liver function abnormal rate were analyzed higher in 40s and 50s when compared to other age levels. AST and ALT were analyzed higher in obesity group than drinking group regarding LFT average rate and liver function abnormal ratio according to levels of drinking and obesity, and GGT was higher in drinking group than obesity group. Higher tendency of LFT risk level was shown in obesity group when compared to drinking group. LFT liver function abnormal rate per BMI was equal in normal weight group of end year when compared to starting year, obesity group had decreased by 3.7%, and LFT liver function abnormal ratio according to drinking habits had decreased by 3.6% in non-drinking group and 1.9% in drinking group, showing 1.7% higher Multi-variate regression analysis was executed in order to examine factors of age and BMI drinking habit that influence AST, ALT, GGT test rates, showing obesity as significant variable of AST, age and obesity as significant variable of ALT, and drinking and obesity as significant variable of GGT. Unlike other studies that have reported increase in drinking rate and obesity rate, the results of this study present reduction in drinking rate, obesity rate, liver-function average rate, and liver function abnormal ratio to recommend efforts to maintain reasonable weight and restrain drinking in case of discovery of liver function abnormality in LFT from results of regular health checkup, and requires special management of liver disease regarding males of 40-50s with high death rate.
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