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      • 胃癌患者에서 水溶性 Intercelular Adhesion Molecule 1의 의의

        김완식 충남대학교 1996 국내박사

        RANK : 247631

        Intercellular adhesion molecule-I is a ligand for the leucocyte integrins CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1): and plays an important role in a variety of inflarmmatory and immune-mediated mechanisms. ICAM-1 mediates effector cell adhesion, activation, and functions in inflammatory and immunologic reactions. Moreover it is suggested that ICAM-1 is involved in the generation of antitumor immune surveillance and cytotoxicity. Elevated serum level was observed in several conditions, such as inflammatory, immune and several malignant diseases. We measured the serum ICAM-1 levels in patients with stomach cancer patients and analyzed it's clinical significance. The results were as follows: 1) A total of 45 patients with stomach cancer were studied: the numbers of patients for stages I, II, III, IV were 10, 9, 11 and 15 respectively. 2) Age distribution was from 30 to 86 years with a median age of 60. 3) Serum ICAM-1 level of stage I patients was 648.0±92.4ng/ml, the difference of which was not significant statistically from the normal control. Those in stage II (798.4±280.0ng/ml), stage III(1054.2±243.5ng/ml) and stage IV patients (1120.5±628.1ng/ml) were significantly higher than that in normal controls. 4) The level in patients with metastasis(stage 4) was higher than that in patients with localized diseases (stage I, II)(p=0.02). 5) Postoperative serum levels in 10 patients who underwent curative gastrectomy were decreased significantly compared with preoperative levels. In conclusion, serum ICAM-1 level was significantly elevated in patients with stomach cnacer(stage II-IV) and especially with metastasis.

      • Rayleigh fading 채널에서의 M-ary PSK와 QAM의 성능비교

        김완식 단국대학교 대학원 1987 국내석사

        RANK : 247631

        대량으로 늘어나는 정보데이타를 효과적으로 전송하기 위한 많은 변조방식들이 유선 또는 무선에 사용되고 있다. 특히 디지탈 무선인 경우 multipath fading현상으로 인하여 bit error가 높아지게 된다. 이와같은 fading의 영향에 대한 디지탈 무선변조방식들의 성능비교를 위하여 많은 fading채널모델들이 제안, 연구되어 왔다. 본 논문에서는 Rayleigh fading 채널모델을 채택하였다. 변조방식으로는 다치변조방식으로 많이 사용되는 M-ary PSK와 QAM을 사용하여 가우스잡음이 섞인 fading채널에서의 오율식을 구하였다. 그리고 구한 오율식으로 수치를 계산하여 S/N비에 대한 Symbol error로서 그래프로 나타내었으며, 가우스 잡음이 섞인 Rayleigh fading채널에서의 두변조방식들의 선택과 이용에 기여할 수 있게 하였다. Many communication channels are subjected to fading which is normally due to multipath characteristics and will almost invariably result in an increase in the error probabilities. There are several available models such as Rummler's three-path (two-path), Nakagami's m-distributed model, and Rayleigh (or Rician) fading channel. Among the above models, one channel model can be chosen to use in evaluating error performance of the used system according to the specific channel conditions. In this paper, the error probabilities of M-ary PSK and QAM are evaluated in terms of signal-to-noise ratio in a Rayleigh fading channel with an Additive White Gaus-sian Noise in the ideal conditions.

      • 문장제의 지도에 대한 연구 : 중학교 1학년 수학과를 중심으로

        김완식 단국대학교 1994 국내석사

        RANK : 247631

        본 논문은 교과서상의 문장제 분포 실태와 학생과 교사의 문장제에 대한 학습 및 지도의 실태를 조사하고 문장제 학습지도에 대한 일반적 이론을 고찰하여 이를 바탕으로 한 문장제 학습의 한 지도 방향을 수립하였다. 문장제 해결에 필요한 사고로는 양불변의 사고, 양의 질적변환의 사고, 전체와 부분의 사고, 가역적인 사고, 대응의 사고, 대입의 사고, 소거의 사고, 신축의 사고, 대수적 사고가 있으며 이들 사고에 의하여 문장제 학습을 위한 지도의 방향이 모색되었는데 그 방향에 의한 지도의 한 사례를 제시 하였다. 문장제 지도는 학생 스스로가 문제의 주인공이 되어 적극적으로 문제풀이에 임할 수 있는 문장제의 발굴이 매우 중요하며 그러기 위해서는 학생과 교사가 함께 문제를 만들어 가는 수학적 활동이 바람직한 것으로 판단된다.

      • FOXO3a activation by natural compounds protects cigarette smoke-induced DNA damage in Rat : Rats에서 천연물에 의한 FOXO3a의 활성화가 담배연기에 의한 DNA damage를 보호한다

        김완식 한림대학교 대학원 2017 국내석사

        RANK : 247631

        Cigarette use has been a major cause of cancer and despite of significant progress in cigarette control, there are still over 1 billion smokers in the world. Cigarette smoke is one of the most important environmental pollutants that cause DNA damage. FOXO3a is one of forkhead family transcription factor and is known to activate various target genes including MnSOD, catalase and GADD45 to remove reactive oxygen species and to repair DNA damage. Although it has been well reported that cigarette smoking resulted in DNA damage and various natural antioxidants could protect from cigarette smoking-induced DNA damage, the underlying mechanism for protection has not been elucidated clearly. To verify this, biochemical examinations of blood, blood cells and liver in CS (cigarette smoke)-inhaled rats were performed. As expected, CS inhaled-rats showed increased ALT and AST as liver damage markers. Numbers of leukocyte as well as NE (neutrophil), LY (lymphocyte), Mo (monocyte), EO (eosino-phill), and BA(basophilis), were increased CS inhaled-rats but these numbers were decreased in CS inhaled-rats treated with natural antioxidants, vitamin C, red ginseng extract, purple corn extract and metformin. The level of γ-H2AX in blood cells without red blood cells was increased in CS inhaled-rats when compared to control rats. However, the level of γ-H2AX was decreased in CS inhaled-rats treated with natural antioxidants. Protein levels of p-AMPK, FOXO3a, p-FOXO3a (Ser413), MnSOD, and XPC were increased in CS inhaled-rats treated with vitamin C, red ginseng extract, purple corn extract and metformin when compared with in CS inhaled-rats. Taken together, the result suggests that administration with natural antioxidant compounds activates FOXO3a and thereby its target genes, MnSOD and XPC are activated for protection from CS-induced DNA damage.

      • 수행평가 활용을 위한 축구기술검사 개발과 타당성 검증

        김완식 경희대학교 2008 국내석사

        RANK : 247631

        The purpose of this study was to investigate validity and reliability of newly developed KLK soccer skill test for the use of performance based evaluation utilized in middle and high school setting. The subjects consisted of 60 college students and divided into three groups; advanced group, intermediate group, and beginner group. The advanced group are highly trained players and member of college soccer team and intermediate group are not highly trained players and member of club. Beginner group are not playing soccer on regular basis and student of non-physical education major. KLK soccer skill test was developed to improve the disadvantages of Mor-Christian soccer skill test in 1979. KLK soccer skill test could be performed in outdoor and wide space which maximally simulated soccer skill in real match. KLK soccer skill test is a battery test consist of dribbling, passing, and shooting skill. The results showed that there was significant group differences in all of the soccer skill at Mor-Christian soccer skill test and KLK soccer skill test. The significant correlation coefficient exists in all the soccer skill test between Mor-Christian soccer skill test and KLK soccer skill test, which means newly developed KLK soccer skill test has reasonable validity. The correlation coefficient changed within each group and thus significant relation was shown only in advanced group. Significant correlation exist in dribbling at intermediate group and dribbling and passing at beginner group. ANOVA and Intraclass correlation coefficient showed that significant reliability of KLK soccer skill test exist in passing and shooting skill test. In conclusion KLK soccer skill test discriminates the levels of soccer skill and showed reliable and valid soccer skill test which could be applied at middle and high school setting for the use of performance based evaluation.

      • 동학 사상의 민족주의적 성격

        김완식 안동대학교 교육대학원 2003 국내석사

        RANK : 247631

        The purpose of this study is to inquire into the nationalistic characters of Donghak Thought(東學思想) by considering the background of the traditional thoughts providing the foundation for Donghak Thought and by analyzing the basic ideologies of Donghak Thought. As the ideological background of Donghak Thought, humanism of one body of God and man, and ideology of Hong-Ik-In-Gan(弘益人間) may be cited from Dan-Gun(檀君) thought, and mercy and egalitarianism from Buddhism, and Tae-Geuk(太極) theory and the thought of sincerity and respectability from Confucianism, and reform and modern-centered thoughts from Sil-Hak(實學) thoughts or thoughts of Practical Science, and folk belief from Taoism. In-Nae-Cheon(人乃天) as the base thought of Donghak was the national spirit that showed the acme of man's dignity and Bo-Guk-An-Min(輔國安民) thought opened the eyes of the people to the national identity and helped maintain the autonomous national independence from the foreign powers and helped the people live in peace. The thought of resistance was the main stream of struggle against the feudalism and foreign powers and showed nationalistic characters by advocating rejection of the foreign powers, and the thought of an earthly paradise contained the thought of constructing the present earthly paradise on earth rather than the future world after death. As the nationalistic characteristics of Donghak Thought the thought of the national creation sought the advancement and improvement of the nation. At the same time it expressed the anti-Japanese, anti-Chinese and anti-Western powers thoughts as resistant nationalistic characteristics. More than anything else, the anti-Chinese thought may be viewed as the historic momentum of announcing the spiritually and ideologically independent line.

      • 膽道 結石에 대한 外科的 處置

        김완식 忠南大學校 大學院 1985 국내석사

        RANK : 247631

        Clinical review was carried out in 131 cases of biliary tract stone disease who were treated surgically at Department of General Surgery of Chungnam University Hospital for 5 years from Jan. 1980.to Dec.1984. The result was as follows: 1) The peak incidence of age was the 5th decade in both sex and the male to female ratio was 1:1.5. 2) The most prominent symptom was pain on the right upper quadrant and the characteristic sign was the tenderness on same site. 3) Of the 131 cases in the biliary tract stone, the gallbladder stone is found in 82 cases(62.5%), common bile duct stone is found in 69 cases(52.7%), and intrahepatic duct stone is found in 12 cases(20.6%). 4) The most common technique of operation is cholecystectomy and T-tube drainage in 70 cases(53.3%), and followed by cholecystectomy in 43 cases(32.8%), cholecystectomy and choledochoduodenostomy in 12 cases(9.2%). 5) The bile culture was positive in 53 cases in which 23 cases was no growth, the majority group is E.coli in 15 cases(28.3%), followed by Enterobacter in 8 cases(15.1%), and proteus in 5 cases(9.4%). 6) Postoperative complication was noted in 27 cases(20.6%)and wound infection was most common in 11 cases(8.3%). 7) The overall mortality rate was 3.8% in 5 cases and cause of death was sepsis(3 cases), bile leakage(2 cases).

      • 英陽 小盆地 南端部의 白堊紀 地層의 層序 및 地史

        김완식 경북대학교 교육대학원 1974 국내석사

        RANK : 247631

        The stratigraphic units of the Kyongsang (Cretaceous) sedimentary rocks distributed in the study area are either thin or absent. This fact led to the concept of the Chongsong ridge. Another significant result of this study is the recognition of the Kisadong Formation that facilitate the correlation of the underlying formations.

      • 光洲市場의 蔬菜類에 관한 細菌學的 硏究

        김완식 朝鮮大學校 大學院 1983 국내석사

        RANK : 247631

        This experiment was carried out to evaluate the sanitary quality of cultured vegetables and to check the removed rate of bacteria by treating methods such as washing with tap water or commercialdetergent, or blanching. Sample such as Fragaria chiloensis var. ananassa. Lycopersicum esculentum, Brassica campestris var. pekinensis , Chrysathemum coronarium, Allium odorum, Oenanthe stolonifera and Lactuca sativa were collected from the major markets located in Gwangju city during the period from May to September in 1983. Fecal coliform MBN was ranged from 180 to 7,000,000 per 100grams of samples examined while plate count was from 7.9 × 10^(3) to 4.6 × 10^(6) per gram. Usually contamination rate of fecal coliform of leaf vegetables was much higher than that of fruit vegetables. In the monthly experiments of Lactuca sativa, the number of sanitary indicative bacteria was highest in August. Removed rate of bacterial density of vegetables by washing three times with tap water was about 20% in leaf vegetables, about 80%by washing with a commercial detergent. Survival rate of viable cell count of leaf vegetables wes less than 0.1 % after blanching for one minute in boiling water. Compositions of coliform group were 17% Escherichia coli group.. 20% Citrobacter freundii group and 63 % Klebsiella aerogenes group, among Escherichia coli group, type Ⅰ was 14% in total. The confirmative rate of coliform group was about 80 % in the IMViC reaction with BGLB gas positive tubes in various vegetables.

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